What are the most significant biomarkers associated with infertility in patients with endometriosis and pelvic pain?

Tripdatabase
2025 · doi:10.5281/zenodo.17809965 · W7108618812
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This paper reviews potential biomarkers for endometriosis-associated infertility, including CA125, nitric oxide, metabolites, and genetic indicators, noting that no single marker has achieved clinical validation.

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This paper reviews current evidence regarding biomarkers associated with infertility in patients suffering from endometriosis and pelvic pain. It highlights several potential candidates, including CA125, nitric oxide, specific metabolites, genetic and epigenetic markers, and indicators of hormonal dysregulation. The authors note that despite the wide array of identified markers, no single biomarker has yet achieved clinical validation for diagnostic use. This paper is centrally about endometriosis — specifically focusing on the identification of biomarkers linked to infertility in this patient population.

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Abstract

Current evidence suggests a wide array of potential biomarkers for endometriosis-associated infertility, but no single marker has yet achieved clinical validation. Highlighted markers include CA125, NO, specific metabolites, genetic/epigenetic markers, and hormonal dysregulation indicators.
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Published November 17, 2025 | Version v1 Other Open What are the most significant biomarkers associated with infertility in patients with endometriosis and pelvic pain? Description Current evidence suggests a wide array of potential biomarkers for endometriosis-associated infertility, but no single marker has yet achieved clinical validation. Highlighted markers include CA125, NO, specific metabolites, genetic/epigenetic markers, and hormonal dysregulation indicators. Files 1234d815-3cc4-461e-8084-f36409d1b81a.pdf Files (18.6 kB) | Name | Size | Download all | |---|---|---| | md5:e64b8b1bb95ec614837aaa379d3a65aa | 18.6 kB | Preview Download |

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endometriosisinfertility

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last seen: 2026-06-10T17:14:06.276822+00:00
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