The lower shear modulus of younger subjects can result in stronger Achilles tendons - an in silico analysis.

The lower shear modulus of younger subjects can result in stronger Achilles tendons - an in silico analysis. | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article The lower shear modulus of younger subjects can result in stronger Achilles tendons - an in silico analysis. Otávio Teixeira Pinto, Bruno Klahr, José Luís Medeiros Thiesen, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3940486/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 25 Apr, 2025 Read the published version in Journal of the Brazilian Society of Mechanical Sciences and Engineering → Version 1 posted 4 You are reading this latest preprint version Abstract Proteins such as the collagen of tendons and other structures of the body tend to form cross-links with their neighbors as a result of aging. These new chemical bonds are known to increase the lateral force transfer between collagen molecules and, as a consequence, increase the shear stresses present in tissues with a high degree of fiber organization such as the Achilles tendon. A finite element model of the Achilles tendon is proposed to compare three levels of lesion severity on two different Achilles tendon models (young and old). The low and high levels of lesion severity show no difference between the old and the young case, but the medium level of severity shows that the lower shear modulus of the young case protects the tendon by resulting in a more homogeneous stress field, whereas the old case shows an increase in the stress concentration near the lesion site. Achilles tendon computational model Aging Tendinopathy Sliding Full Text Cite Share Download PDF Status: Published Journal Publication published 25 Apr, 2025 Read the published version in Journal of the Brazilian Society of Mechanical Sciences and Engineering → Version 1 posted Reviewers agreed at journal 20 Feb, 2024 Reviewers invited by journal 20 Feb, 2024 Editor assigned by journal 09 Feb, 2024 First submitted to journal 07 Feb, 2024 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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