Clinical analysis of 18 cases of ovarian clear cell carcinoma

Objective:To analyse the clinical and pathological characteristics and prognosis of ovarian clear-cell carcinoma, and its relation with endometriosis. Methods: Eighteen cases with primary ovarian clear-cell carcinoma patients were analyzed retrospectively. Results: As compared with the ovarian serous cystadenocarcinoma, the patients with ovarian clear cell carcinoma more often had unusual menstrual cycle or postmenopause bleeding, took place in unilateral ovary, accompanied with endometriosis and the proportion of FIGO stage I was higher. The incidence of endometriosis showed no significant difference between the groups. Conclusion: Unlike other ovarian epithelial carcinoma, clear cell carcinoma's clinical stage is early but isn't sensitive to chemotherapy. It easily recurs at early time with poor prognosis. Pathological results don't show any correlation between endometriosis and the prognosis of ovarian clear-cell carcinoma.The prognosis of ovarian clear cell carcinoma is correlated with clinical staging, size of tumours, presence of ascites, the degree of dissemination, invasion of one or both sides of the ovary and differentiation of the tumour cells.