Effects of various hemostasis approaches on ovarian reserve after laparoscopic cystectomy in patients with ovarian cyst

Objective To investigate the effects of various hemostasis approaches on ovarian reserve after laparoscopic cystectomy in patients with ovarian cyst. Methods We randomly assigned patients with ovarian cyst, based on the approaches for hemostasis employed during the surgery, to electric coagulation group (n=34), ultrasound knife group (n=34) and suture group (n=34), respectively. Serum estradiol (E2), follicular stimulating hormone (FSH) and luteinizing hormone (LH) were examined prior to the operation and at months 1 and 3 post-operatively, via chemiluminescence assay. The ovarian reserve was tested by using transvaginal color Doppler ultrasonography at month 3 post-operatively. Results There was no significant difference in serum FSH, LH and E2 among the three groups (P0.05) prior to surgery. As compared with pre-operative levels, both electric coagulation group and ultrasound knife group, but not suture group (P0.05), resulted in increased FSH and LH at months 1 and 3 post-operatively (both P0.05). All groups showed reduced antral follicle count in the operated side at month 3 post-operatively (all P0.05). Conclusion Suture hemostasis during laparoscopic cystectomy does not influence ovarian reserve in patients with ovarian cyst inasmuch that normal ovarian tissues are retained during the surgery.