Are ABO and Rh blood groups new genetic risk factors for endometriosis?

K Daliri, Daliri K, Kaoru Tabei, S M Tabei, A Amini, Ali Amini, Hossein Derakhshankhah, H Derakhshankhah
Archives of gynecology and obstetrics · 2013 · doi:10.1007/s00404-013-2844-6 · PMID:23595583
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This paper investigates whether ABO and Rh blood groups are genetic risk factors for endometriosis, referencing previous studies on the topic.

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This study investigated whether ABO and Rh blood groups serve as genetic risk factors for endometriosis by analyzing the distribution of these blood types in a cohort of patients diagnosed with the condition. The authors compared their findings against existing literature, noting that previous small-scale studies had yielded inconsistent results regarding any potential association between specific blood groups and disease susceptibility. The paper concludes that while there may be slight variations in blood group frequencies among endometriosis patients, larger and more rigorously designed projects are needed to definitively establish a causal link or significant correlation. Relevance to endometriosis: Centrally about the condition, this paper directly investigates the potential role of ABO and Rh blood groups as genetic risk factors for endometriosis.

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References Vinatier D, Orazi G, Cosson M et al (2001) Theories of endometriosis. Eur J Obstet Gynecol Reprod Biol 96:21–34 Zondervan KT, Cardon LR, Kennedy SH (2001) The genetic basis of endometriosis. Curr Opin Obstet Gynecol 13:309–314 Amundadottir L, Kraft P, Stolzenberg Solomon RZ et al (2009) Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 41(9):986–990 Montgomery GW, Nyholt DR, Zhao ZZ et al (2008) The search for genes contributing to endometriosis risk. Hum Reprod Update 14:447–457. doi:10.1093/humupd/dmn016 Matalliotakis I, Cakmak H, Goumenou A et al (2009) ABO and Rh blood groups distribution in patients with endometriosis. Arch Gynecol Obstet 280:917–919 Demir B, Dilbaz B, Zahran B (2009) ABO and Rh blood groups distribution in patients with endometriosis. Arch Gynecol Obstet 281:373–374 An Kim D, You Kim T (2010) Associations of ABO blood groups with various gynecologic diseases. Arch Gynecol Obstet 282:229–230 Tabei SM, Daliri K, Amini A (2012) The investigation of ABO and Rh blood groups distribution in patients with endometriosis needs new project design. Arch Gynecol Obstet 285(5):1487–1488 Conflict of interest None. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Daliri, K., Tabei, S.M., Amini, A. et al. Are ABO and Rh blood groups new genetic risk factors for endometriosis?. Arch Gynecol Obstet 288, 961–963 (2013). https://doi.org/10.1007/s00404-013-2844-6 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-013-2844-6

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Condition tags

endometriosis

MeSH descriptors

ABO Blood-Group System Endometriosis Endometriosis Rh-Hr Blood-Group System Case-Control Studies Endometriosis Female Humans Iran Risk Factors

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