Fibrinogen Is an Independent Preoperative Predictor of Hospital Length of Stay Among Patients Undergoing Coronary Artery Bypass Grafting

Objective: ： This study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and length of postoperative hospital stay (LOPS) of patients undergoing Coronary Artery Bypass Grafting (CABG). Methods: ： Between January 2010 and June 2022, a retrospective analysis comprised 936 patients who sequentially received isolated, primary off-pump or on-pump CABG. The preoperative fibrinogen concentration, baseline index, intraoperative data, ICU stay duration, and LOPS were documented. The prime endpoint was LOPS. Evaluation of the link between preoperative fibrinogen concentration and LOPS was accomplished through the use of univariate as well as multiple linear regression. Results: : Preoperative low fibrinogen concentration (B= -0.072, P = 0.03), male gender (B = 0.066, P =0.04), and elevated K concentration (B = -0.078, P =0.01) were associated with prolonged LOPS. preoperative fibrinogen concentration (B= -0.073, P = 0.03) and plateletcrit (PCT) (B= -0.121, P ＜ 0.01) were also related with the volume of postoperative bleeding. Conclusions: : Fibrinogen is an independent preoperative predictor of both the LOPS and the volume of bleeding that occurs after CABG. Patients whose preoperative fibrinogen concentration was low experienced a greater loss of blood and a longer LOPS. A greater preoperative K concentration and male gender were associated with a longer LOPS.