Sind Präeklampsie-Marker hilfreich bei der Endometriose-Diagnostik? – Eine Fallserie
This case series examines the utility of the placental growth factor to soluble fms-like tyrosine kinase-1 quotient for endometriosis diagnosis, a parameter previously uninvestigated in this context despite known angiogenic alterations.
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This case series investigated whether the sFlt-1/PlGF ratio, a marker used for preeclampsia diagnosis, could aid in identifying endometriosis. The study measured serum levels of placental growth factor and soluble fms-like tyrosine kinase-1 in eleven women undergoing laparoscopy for suspected endometriosis, with histological confirmation obtained post-surgery. Results showed no significant trend toward altered values for these markers or their quotient across different stages of the disease, leading to the early termination of the recruitment process. Consequently, the authors concluded that determining this specific angiogenic quotient offers no diagnostic advantage for endometriosis. This paper is centrally about endometriosis — specifically evaluating a potential biomarker for its diagnosis.
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