Biosynthesis of silver nanoparticles from Rhaphidophora pertusa leaves extract and its characterization, antimicrobial, anti-oxidant and cytotoxicity activities

The current study investigated the bio-synthesis of AgNPs (silver nanoparticles) through the use of an extract from the leaves of Rhaphidophora pertusa (R.pertusa) . Visual confirmation of the formation of biosynthesized R.pertusa silver nanoparticles (RP-AgNPs) came from observing the colour difference between them. Additionally, it has been examined through FT-IR, HR-SEM, EDAX, XRD, HR-TEM and DLS. At 424 nm the presence of AgNPs has been confirmed by UV-vis spectra. FT-IR reveals the secondary molecules of R.pertusa which are bound with AgNPs contain OH and NH functional groups. The synthesised particles' sizes are validated by HR-TEM which is approximately 19 nm, whereas EDAX investigations have substantiated the existence of AgNPs. The FCC crystallinity of the synthesised RP-AgNPs is confirmed by the XRD report. The size distribution of the particles with a range of 177 nm is discovered using DLS analysis. Significant antioxidant properties are displayed by the bio-synthesised RP-AgNPs for DPPH. Furthermore, it was found that RP-AgNPs are extremely receptive to both thick peptidoglycan and thin peptidoglycan microbes. The MCF-7 cell line is used to test the cytotoxicity of the synthesised RP-AgNPs and the research shows that the MCF-7 cell proliferation is effectively inhibited by the synthesised RP-AgNPs. As a result, the present research findings have enormous potential for the delivery of medication.