Enduring Through Care: A Systematic Review of Resilience, Social Support, and Psychological Well-Being in Hemodialysis Patients

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Abstract Background: Hemodialysis (HD) patients face profound physical and psychosocial burdens that impact treatment adherence, quality of life, and caregiver well-being. Resilience, social support, self-efficacy, and spiritual health are increasingly recognized as critical factors shaping patient outcomes. Objective: This systematic review synthesizes evidence from six observational studies on the associations between psychosocial factors resilience, social support, self-efficacy, and spirituality and health outcomes in HD patients, while identifying implications for nursing practice and future research. Methods: Following PRISMA 2020 guidelines, six core studies (provided by the researcher) were critically analyzed for methodology, outcomes, and findings. To enrich the synthesis, an additional 20 peer-reviewed articles (2020-2025) from Scopus were systematically reviewed. Thematic synthesis was employed to identify patterns across psychosocial domains and patient-centered outcomes. Results: All six studies (cross-sectional) reported consistent positive correlations: higher resilience, perceived social support, self-efficacy, and spiritual well-being were linked to improved treatment adherence, enhanced quality of life, reduced psychological distress, and lower caregiver burden. Family support emerged as a key enabler, while internal coping mechanisms and existential meaning contributed to emotional adaptation. A summary table outlines study characteristics and findings. Thematic analysis highlighted the interdependence of personal strength and relational care in sustaining well-being. Conclusion: Psychosocial factors are vital determinants of holistic outcomes in hemodialysis. Nurses play a pivotal role in recognizing and nurturing resilience, facilitating family involvement, and integrating spiritual care. Future efforts should prioritize prospective and interventional studies to develop evidence-based, person- centered nursing models.
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Enduring Through Care: A Systematic Review of Resilience, Social Support, and Psychological Well-Being in Hemodialysis Patients | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Systematic Review Enduring Through Care: A Systematic Review of Resilience, Social Support, and Psychological Well-Being in Hemodialysis Patients yadekurniasari This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7733545/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Hemodialysis (HD) patients face profound physical and psychosocial burdens that impact treatment adherence, quality of life, and caregiver well-being. Resilience, social support, self-efficacy, and spiritual health are increasingly recognized as critical factors shaping patient outcomes. Objective: This systematic review synthesizes evidence from six observational studies on the associations between psychosocial factors resilience, social support, self-efficacy, and spirituality and health outcomes in HD patients, while identifying implications for nursing practice and future research. Methods: Following PRISMA 2020 guidelines, six core studies (provided by the researcher) were critically analyzed for methodology, outcomes, and findings. To enrich the synthesis, an additional 20 peer-reviewed articles (2020-2025) from Scopus were systematically reviewed. Thematic synthesis was employed to identify patterns across psychosocial domains and patient-centered outcomes. Results: All six studies (cross-sectional) reported consistent positive correlations: higher resilience, perceived social support, self-efficacy, and spiritual well-being were linked to improved treatment adherence, enhanced quality of life, reduced psychological distress, and lower caregiver burden. Family support emerged as a key enabler, while internal coping mechanisms and existential meaning contributed to emotional adaptation. A summary table outlines study characteristics and findings. Thematic analysis highlighted the interdependence of personal strength and relational care in sustaining well-being. Conclusion: Psychosocial factors are vital determinants of holistic outcomes in hemodialysis. Nurses play a pivotal role in recognizing and nurturing resilience, facilitating family involvement, and integrating spiritual care. Future efforts should prioritize prospective and interventional studies to develop evidence-based, person- centered nursing models. Urology & Nephrology Nursing Educational Psychology Physical Medicine & Rehab Hemodialysis patients Psychological resilience Social support Quality of life Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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