A CLINICO PATHOLOGICAL STUDY OF LEIOMYOMA UTERUS IN A TERTIARY CARE REFERRAL HOSPITALAND RESEARCH INSTITUTE

Background And Objectives: Leiomyoma of the uterus is the most common benign tumor of the uterus and also most common pelvic tumor in women. Surgery has been the main mode of therapy for the leiomyomas. Recent trend has been towards non surgical approaches. This study is an attempt to analyse the clinico pathological spectrum in cases of leiomyoma of the uterus in Vani Vilas Hospital and Bowring and Lady Curzon Hospital to know the pattern of presentation, pathological co relation with type of broid and endometrial and ovarian changes. Methods: A cross sectional study of 200 cases of leiomyoma uterus was made in Vani Vilas Hospital and Bowring and Lady Curzon Hospital attached to Bangalore Medical College and Research Institute, Bangalore, from November 2011 to August 2013. The cases were selected by random sampling. Detailed history, gynecological examination and relevant investigations including ultrasonography was done. Results: Leiomyoma is commonly found in the third decade in 58% cases. Most common mode of presentation is menstrual disturbances in 78% amongst which menorrhagia seen in 58% cases, intramural broids are the most common variety accounting for 60.8%, endometrial pattern was proliferative in 68%, cystic ovaries noted in 12% patients and adenomyosis in 19% cases. Interpretation And Conclusion: rd Leiomyoma commonly affects women of childbearing age, most common in 3 decade. Most common presentation is menstrual disturbances. Intramural broid is the most common variety. Presence of proliferative endometrium, adenomyosis and cystic ovaries are all indicative of hyperestrogenic state which is associated with development of leiomyomas.