Assisted Reproductive Technology: Techniques and Limitations

In: Journal of Bangladesh College of Physicians and Surgeons · 1970 · vol. 26(3) , pp. 135–141 · doi:10.3329/jbcps.v26i3.4197 · W1997285937
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This review of assisted reproductive technology identifies endometriosis as a common indication for treatment while highlighting limitations such as high costs, invasive procedures, and modest pregnancy rates.

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This review examines the techniques and limitations of assisted reproductive technology, highlighting that infertility affects one in six couples with ten percent requiring medical intervention. The authors identify bilateral tubal block and endometriosis as primary indications for treatments such as in-vitro fertilization and intracytoplasmic sperm injection, noting that these procedures involve invasive oocyte collection and superovulation risks. While average pregnancy rates remain between thirty and thirty-four percent globally, the text acknowledges higher abortion and congenital anomaly rates linked to maternal age rather than the procedure itself, alongside barriers like cost and social stigma. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Infertility is a source of social and psychological suffering for both men and women and can place great pressure on the relationship within the couple. One in six couples of any society remains infertile and 10% of them need help of assisted reproductive technology (ART). ART refers to all technology where gametes are manipulated outside the body. In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are the commonest of all type of ART. Bilateral tubal block, endometriosis, severe oligospermia, and azoospermia are the commonest indications for ART. Whoever is responsible for infertility women are usually treated for superovulation, which sometimes involves risk of the patient. Collection of oocyte is also invasive. Result of treatment in terms of pregnancy is not very satisfactory. Average pregnancy rate is 30%- 34% worldwide. Abortion and congenital anomaly rate is a bit higher than normal population, which is related to age of the female partner not related to the procedure. There are a number of barriers in this treatment like high cost of treatment, poor result, social stigma and superstitious believe. In addition to creating family by means of assisted reproductive technology, it has made a new dimension for distressed infertile couple. DOI: 10.3329/jbcps.v26i3.4197 J Bangladesh Coll Phys Surg 2008; 26: 135-141
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Assisted Reproductive Technology: Techniques and Limitations Keywords: Assisted Reproductive TechnologyAbstract Infertility is a source of social and psychological suffering for both men and women and can place great pressure on the relationship within the couple. One in six couples of any society remains infertile and 10% of them need help of assisted reproductive technology (ART). ART refers to all technology where gametes are manipulated outside the body. In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are the commonest of all type of ART. Bilateral tubal block, endometriosis, severe oligospermia, and azoospermia are the commonest indications for ART. Whoever is responsible for infertility women are usually treated for superovulation, which sometimes involves risk of the patient. Collection of oocyte is also invasive. Result of treatment in terms of pregnancy is not very satisfactory. Average pregnancy rate is 30%- 34% worldwide. Abortion and congenital anomaly rate is a bit higher than normal population, which is related to age of the female partner not related to the procedure. There are a number of barriers in this treatment like high cost of treatment, poor result, social stigma and superstitious believe. In addition to creating family by means of assisted reproductive technology, it has made a new dimension for distressed infertile couple. DOI: 10.3329/jbcps.v26i3.4197 J Bangladesh Coll Phys Surg 2008; 26: 135-141 651 3338 Downloads How to Cite Issue Section License Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Bangladesh College of Physicians and Surgeons and may not be reproduced by any means in whole or in part without the written consent of the publisher. No part of the materials published in this journal may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Reprints of any article in the Journal will be available from the publisher.

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