The clinicopathological and prognostic characteristics of mucinous micropapillary carcinoma of the breast

Background: Mucinous micropapillary carcinoma (MMPC) is a unique subtype of breast cancer and detailed investigation of clinical characteristics of MMPC is not fully investigated. Methods MMPC, pure mucinous breast carcinoma (PMBC) and invasive micropapollary carcinoma (IMPC) samples were enrolled simultaneously and performed immunohistochemistry (IHC) analysis to explore the clinicopathological attributes of MMPC. Moreover, survival analysis of MMPC were performed among MMPC, PMBC and IMPC group and within MMPC group. Results The result showed that MMPC demonstrated distinct pathological features and vascular invasion, lymph node metastasis were two significant clinical attributes of MMPC. MMPC encountered a decreased survival time than PMBC but an increased survival time than IMBC while TNM stage and lymph node metastasis were identified as two independent prognostic elements for DFS of MMPC prognosis. Conclusions The data implied that further understanding and classification of MMPC may provide better individualized therapeutic strategies for MMPC treatment.