Endometriosis
This review traces the historical development of endometriosis and adenomyosis, highlighting early contributions by Recklinghausen and Cullen and Sampson’s subsequent theories on their histopathogenesis.
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This historical overview traces the early development of endometriosis as a recognized pathological entity, beginning with Recklinghausen’s 1896 monograph. It highlights subsequent contributions by Cullen and Sampson, whose work in the 1920s established foundational theories regarding the histopathogenesis of the disease through studies on adenomyosis. The text serves as a brief biographical and historical summary rather than presenting new clinical data or experimental results. This paper is centrally about endometriosis — specifically its historical definition and early pathogenetic theories proposed by pioneering researchers.
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