Pathological And Clinical Factors Leading To Hysterectomies

Objective: To evaluate the pattern and frequency of premalignant, malignant and benign lesions in hystrectomized uteri and execute clinic-pathological investigation. SETTING: collection of various hysterectomy samples from Nishtar Hospital Multan was carried out. These specimens were studied in the histopathology departments of these medical universities. Duration of the study was from January 2016 to December 2017. Methods:100 cases were selected who were undergoing hysterectomy. They were selected randomly for the detailed study. Afterwards, clinic-pathological examination was carried out. Most of the females undergoing hysterectomy were aged from 25-75 years. Two separate forms were prepared to note down the clinical details and record histopathological results. Preservation of the samples was executed in 10 percent formalin. They were comprehensively examined accordingly. Process of Representative blocks for paraffin embedding was performed. Results: The most frequent complaint was abnormal menstrual flow. 43.06 ±7.34 years was mean age of the patients. From the randomized study of one hundred cases, the most common findings were related to endometrial diseases (67 percent of the patients). Adenomyosis was found in 47 percent of the cases whereas leiomyoma was noted in 32 percent of the cases. Invasive cervical carcinoma was in 03 percent and cervical intraepithelial neoplastic changes were found as 04 percent of the cases. Conclusion:To sum up the findings, benign uterine lesions were frequent which encompasses adenomyosis, endometrial hyperplasia and leiomyoma. These are equally seen in females in Multan whose ages are above or below of 40 years. However, with two exceptions of invasive cervical carcinoma and endometrial carcinoma which were mostly noted in the women aged above 40 years. Key Words: Cervical Carcinoma, Endometrial Hyperplasia, Hysterectomy, Endometrial carcinoma and Leiomyoma.