Antiendometrial Antibody and Endometriosis

Objective To study the relationship between the antiendometrial antibodies (EMAb) and the endometroisis. Methods: A modified isolation method of endometrial antigen (EMAg) has been developed; amino acids of the EMAg was analysed by SDSPAGE and Western Blot; the serum levels of the EMAb were detected by ELISA between the normal human and the patient with the endometriosis. Results There are two bands in the normal human EMAg, including 48 .0 kD and larger than 97.4 kD, the latter can react specifically with the EMAb. But, there are three bands in the patients with endometriosis, including 46.0 kD54.0 kD and larger than 97.4 kD, in which all three bands can react with the EMAb. In another, there are different animo acids in kind and contents in the EMAg between the normal human and patients with the endometriosis. There are significantly different in serum EMAb between the patients with the endometriosis and nonendometriosis as well as the normal human ( P 0.05). ConclusionThere are significantly relationship between the EMAb and the endometriosis.