Retrospective Comparison Between Laparoscopic and Open Malignant Gastrectomy Performance and Outcome

Laparoscopy is rarely used to treat stomach malignancies. We compared the outcomes of laparoscopic gastrectomy with those of open surgery and evaluated the results. However, its complete acceptance as a legitimate therapy is hampered by the lack of thorough investigation into long-term oncological consequences, including recurrence and fatality. As a result, there are sometimes arguments over which of these remedies is the best. Therefore, there is still debate regarding the best outcome. Methods: We will evaluate patients who underwent laparoscopic gastrectomy and open gastrectomy from February 2015 to November 2022. After collecting the database from the board sheet of our Zagzig University Hospital specialist surgical hospital, patients were divided into two groups: open surgery and laparoscopic surgery. Logistic regression was used to compare 30-day complications and fatalities in both groups. Results: For consistent results, the mean difference (MD) or standardized mean difference (SMD) and 95% confidence interval (CI) were calculated. The meta-analysis was conducted using Review Manager 5.3 and STATA software. A total of 8,232 gastric cancer patients were divided into two groups based on the type of surgery they received: open gastrectomy (n= 7,450; 90.5%) and laparoscopic surgery (n = 782; 9.5%). Preoperative measurement of risk variables is important (CI = 0.45-0.82, p = 0.001, odds ratio [OR] 0.61, 95% confidence interval). We found no significant differences in mortality between groups when the preoperative risk variable was measured (OR = 0.74; 95% CI = 0.32-1.72; p = 0.481).