Lung ultrasound to evaluate pulmonary changes in patients with cardiogenic shock undergoing extracorporeal membrane oxygenation:A retrospective study

Purpose: The aim of the study was to evaluate the value of lung ultrasound (LUS) in patients with cardiogenic shock treated by venoarterial extracorporeal membrane oxygenation (VA-ECMO). Methods: : A retrospective study was conducted in Xuzhou Central Hospital from September 2015 to April 2022. Patients with cardiogenic shock who received VA-ECMO treatment were enrolled in this study. The LUS score was obtained at the different time points of ECMO. Results: : Twenty-two patients were divided into a survival group (n=16) and a nonsurvival group (n=6). The ICU mortality was 27.3% (6/22). The LUS scores in the nonsurvival group were significantly higher than those in the survival group after 72 h (P<0.05). There was a significant negative correlation between LUS scores and PaO 2 /FiO 2 and LUS scores and Cdyn after 72 h of ECMO treatment ( P <0.001). ROC curve analysis showed that the area under the ROC curve (AUC) of T 72 -LUS for predicting ICU mortality was 0.964 (95% CI 0.887~1.000, P<0.01). Conclusion: LUS is a promising tool for evaluating pulmonary changes in patients with cardiogenic shock undergoing VA-ECMO. Moreover, T 72 -LUS can effectively predict the ICU survival status of patients. Trial registration: The study had been registered in the Chinese Clinical Trial Registry(NO.ChiCTR2200062130 and 24/07/2022).