Culture conditions antagonize lineage-promoting signaling in the mouse blastocyst
preprint
OA: closed
CC-BY-NC-ND-4.0
Abstract
The mouse preimplantation embryo is a paradigm for discovery of the molecular principles governing formation of specific cell types during development. We show that conditions commonly used for ex vivo culture of preimplantation development are themselves antagonistic to a pathway that is critical for blastocyst lineage commitment.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-08-12T06:43:03.944938+00:00
License: CC-BY-NC-ND-4.0