[Inhibitory effects of Sanleng pellet on angiogenesis of endometriosis in rats].

Yi Chen, Chen Y, Xiaoyu Xu, Xiao-Yu Xu, Xu XY, Ye L, Lan Ye, Zhu HF, Hui-Fengi Zhu, Hong Chen, Chen H, Gong Chen, Chen G
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2008 · vol. 33(3) , pp. 303–7 · PMID:18536472 · W2467874341
article OA: closed CC0 ⤵ 1 in-corpus citation
View on OpenAlex View on PubMed
⚙ AI-generated summary by claude@2026-07, 2026-07-18 ⓘ

Sanleng pellet reduced microvessel density and inhibited vascular endothelial growth factor and TNF-alpha expression in ectopic endometriotic tissue of rats.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: To investigate the effect of Sanleng pellet on angiogenesis of endometriosis in SD rats. METHOD: The rat model of endometriosis were treated with Sanleng pellet. Observe microvessels density by immunohistochemical test as well as the expression of vascular endothelial growth factor and tumor necrosis factor-alpha in ectopic endometriotic tissue by immunohistochemical test and RT-PCR. RESULT: Sanleng pellet can reduce MVD, and inhibit the level of protein and mRNA of vascular endothelial growth factor and TNF-alpha in ectopic endometriotic tissue. CONCLUSION: Sanleng pellet can reduce the degree of angiogenesis in the endometriosis rats, and its mechanism might be associated with inhibiting the expression of vascular endothelial growth factor and TNF-alpha in the heterotopic tissue.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Drugs, Chinese Herbal Endometriosis Neovascularization, Pathologic Animals Drugs, Chinese Herbal Endometriosis Endometriosis Female Immunohistochemistry Neovascularization, Pathologic Rats Reverse Transcriptase Polymerase Chain Reaction Tumor Necrosis Factor-alpha Tumor Necrosis Factor-alpha Tumor Necrosis Factor-alpha Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor A

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (1)

Cited by (1)

Source provenance

europepmc
last seen: 2026-08-08T06:08:32.324769+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:14:30.652814+00:00
License: CC0 · commercial use OK