Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study

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Also, in order to achieve healthy static and dynamic occlusal interactions, the teeth must be positioned within the basal bone at the correct position, angle, and inclination. To avoid periodontal issues, provide stability, and achieve a functional occlusion, it is essential to ascertain the individual’s dental arch form before starting of treatment and thus to utilise the mechanics that follow throughout the treatment. Objectives To evaluate and compare variation in Curve of Spee and Curve of Wilson in Class II Div.-1, Class II-Div-2 and Class-III as against Class I malocclusion in central India population. Methodology Irreversible hydrocolloid impression will be taken with perforated metal stock trays and stone cast will be poured. This will be scanned using CAD CAM machine and curve of Spee and Wilson will be measured using reverse engineering. Expected Result It will assist us in treatment planning for preventing periodontal issues, assuring stability, and achieving functional occlusion by evaluating and comparing the Spee and Wilson curves in Class II Divison-1, Class II Divison-2, and Class-III malocclusion with Class-I malocclusion. Conclusion Every single patient receiving orthodontic treatment has the COS, which is crucial to achieving a stable occlusion. Almost every patient who receives orthodontic treatment eventually experiences the Spee Curve. Since there aren’t many studies examining the relationship between the Curves of Spee and Wilson, their impact on dentoskeletal morphology, and their role in occlusal stability. 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F1000Research 2024, 12 :493 ( https://doi.org/10.12688/f1000research.133330.3 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. Close Copy Citation Details Export Export Citation Sciwheel EndNote Ref. Manager Bibtex ProCite Sente EXPORT Select a format first Track Share ▬ ✚ Study Protocol Revised Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] Ruchika Pandey https://orcid.org/0000-0001-5713-2424 1 , Ranjit Kamble 2 Ruchika Pandey https://orcid.org/0000-0001-5713-2424 1 , Ranjit Kamble 2 PUBLISHED 10 Jul 2024 Author details Author details 1 Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India 2 Professor, Orthodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India Ruchika Pandey Roles: Conceptualization, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Ranjit Kamble Roles: Supervision, Validation OPEN PEER REVIEW DETAILS REVIEWER STATUS This article is included in the Datta Meghe Institute of Higher Education and Research collection. Abstract Introduction Getting acceptable cosmetic results in the soft tissues of the face serves as the foundation for orthodontic treatment planning. Also, in order to achieve healthy static and dynamic occlusal interactions, the teeth must be positioned within the basal bone at the correct position, angle, and inclination. To avoid periodontal issues, provide stability, and achieve a functional occlusion, it is essential to ascertain the individual’s dental arch form before starting of treatment and thus to utilise the mechanics that follow throughout the treatment. Objectives To evaluate and compare variation in Curve of Spee and Curve of Wilson in Class II Div.-1, Class II-Div-2 and Class-III as against Class I malocclusion in central India population. Methodology Irreversible hydrocolloid impression will be taken with perforated metal stock trays and stone cast will be poured. This will be scanned using CAD CAM machine and curve of Spee and Wilson will be measured using reverse engineering. Expected Result It will assist us in treatment planning for preventing periodontal issues, assuring stability, and achieving functional occlusion by evaluating and comparing the Spee and Wilson curves in Class II Divison-1, Class II Divison-2, and Class-III malocclusion with Class-I malocclusion. Conclusion Every single patient receiving orthodontic treatment has the COS, which is crucial to achieving a stable occlusion. Almost every patient who receives orthodontic treatment eventually experiences the Spee Curve. Since there aren’t many studies examining the relationship between the Curves of Spee and Wilson, their impact on dentoskeletal morphology, and their role in occlusal stability. READ ALL READ LESS Keywords Curve of Spee, Curve of Wilson, Occlusion, Functional occlusion Corresponding Author(s) Ruchika Pandey ( [email protected] ) Close Corresponding author: Ruchika Pandey Competing interests: No competing interests were disclosed. Grant information: The author(s) declared that no grants were involved in supporting this work. Copyright: © 2024 Pandey R and Kamble R. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. How to cite: Pandey R and Kamble R. Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.12688/f1000research.133330.3 ) First published: 15 May 2023, 12 :493 ( https://doi.org/10.12688/f1000research.133330.1 ) Latest published: 10 Jul 2024, 12 :493 ( https://doi.org/10.12688/f1000research.133330.3 ) Revised Amendments from Version 2 We have added the reason for not using intraoral scanner directly in the manuscript. We have added the reason for not using intraoral scanner directly in the manuscript. See the authors' detailed response to the review by Luz Andrea Velandia Palacio See the authors' detailed response to the review by Liliana Ávila Maltagliati See the authors' detailed response to the review by Vabitha Shetty and Dinesh Rao READ REVIEWER RESPONSES Introduction Background and rationale Planning for orthodontic treatment begins with achieving acceptable cosmetic outcomes in the soft tissues of the face. In order to achieve healthy static and dynamic occlusal interactions, it is also crucial to place the teeth in the basal bone with the correct angulation, inclination, and location. In order to prevent periodontal disease, provide stability, and achieve a functional occlusion, it is critical to identify the patient’s dental arch form before commencing treatment so that mechanics can be used to conform arch form throughout the therapy. Periodontal problems in teeth are caused by teeth moved orthodontically that go beyond the basal border and compromise the stability after treatment. The occlusal plane should be flattened and the Wilson Curve should be levelled as the end results of orthodontic therapy. 1 The human dentition exhibits the natural phenomenon known as Curve of Spee (COS). For a successful masticatory system, the anteroposterior curve of occlusion is necessary. 2 In 1890, F. Graf von Spee (1855-1937), German anatomist, described the Curve of Spee. He discovered that the occlusion line in skulls with worn away teeth was a line on a cylinder perpendicular to the mandibular incisors’ incisal borders, surface of occlusal of 2 nd molar, and the anterior border of the condyle. 3 The COS, which is essential to attaining a stable occlusion, is present in every single patient undergoing orthodontic treatment. In orthodontics, the arc that is perpendicular to the incisal margins is currently referred to as the “Curve of Spee”. 4 Recent studies have shown that the mediolateral curve plays a biomechanical role in mastication by improving the efficacy of forces of occlusion during mastication and the crush/shear ratio between the posteriors. Dental malocclusions with significant overbites typically have an inflated Curve of Spee. 3 As a result, there will be an inappropriate functional occlusion since the muscle imbalance will be altered. Wilson was the very first to distinguish the lower grinding teeth’s lingual inclination and the higher grinding teeth’s buccal inclination. The Curve of Wilson is the name given to this occlusal curve in the coronal plane. The Wilson Curve allows for lateral mandibular excursions without posterior obstructions. 2 For adequate function, the amount of buccolingual tooth inclination must be determined and quantified in order to support treatment objectives. 2 The palatal and buccal cusps of the posteriors are in functional contact as a result of this curvature, which appears to necessitate a concave mandibular arch as well as a concave and convex maxillary arch. 5 It would be logical to expect that the incline of bone would be oriented in this direction for the best masticatory stress given the alignment of the anatomical parts outlined by Dawson. Okeson outlined the purpose of the Curve of Wilson, which prevents balancing interferences and ensures the most efficient utilisation of cuspal contacts. 2 Andrews came up with 6 keys of normal occlusion out of which 3 rd key is tooth inclination, which is the labiolingual as well as buccolingual inclination of the crown. He saw a lingual tilt in the posterior crowns of the mandible and maxilla. 2 One of the elements included in the six keys to occlusion is the Curve of Spee. According to Andrews, COS in people with proper occlusion varies from flat to moderate. 1 The COS and COW in the lower arches of people living in central India will be determined in this study. In this study, reverse engineering is used to determine the Wilson curve and the Spee curve, which is useful for understanding its comprehensiveness as well as the impact it has on stable occlusion. The measurement and significance of compensatory curves have also been discussed in various studies. In literatures prior to our study, some of the compensatory curves were shown to be correlated with dentoskeletal malocclusions and normal occlusion. The link between the Curves of Spee and Wilson and their effect on morphology of dentoskeletal, their potential to maintain stability of occlusion have all been the subject of a few studies. This investigation investigates the connection between compensatory curves and how it might aid in the development of treatment plans for specific malocclusions. Objectives • To evaluate Curve of Spee and Curve of Wilson in Class II Div.-1, Class II Div.-2 and Class-III malocclusion in central India population. • To evaluate Curve of Spee and Curve of Wilson in Class-I malocclusion in central India population. • To compare variation and relationship between Curve of Spee and Curve of Wilson in Class II Div.-1, Class II Div.-2 malocclusion and Class-III as against Class I malocclusion in central India population. Trial design: In-vitro study Protocol Study setting Following study will be done at the Department of Orthodontics and Dentofacial Orthopedics, Sharad Pawar Dental College, Sawangi (M), Wardha, in cooperation with the Department of Prosthodontics. Eligibility criteria Inclusion criteria: • Patients of age group between 14-30 years. • Complete permanent dentition except third molars considering it is the tooth that is most frequently lost owing to extraction or congenital tooth loss. Exclusion criteria: • Patient with previous orthodontic treatment. • Patient with ongoing orthodontic treatment. • Patient with missing or impacted teeth. • Patient with systemic disease. • Patient with previous record of trauma or surgery. • Severe caries. • Severe occlusal wear. Intervention • The study will be conducted on patients coming to the Department of Orthodontics and Dentofacial Orthopedics and diagnosed with Class I, Class ІІ div-1 and Class II div-2 & Class III malocclusion will be selected for the study. • Written informed consent will be obtained from all the participants. • Irreversible hydrocolloid impression will be taken with perforated metal stock trays and stone cast will be poured. Due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. This will be scanned using CAD CAM machine which allows us to work on machine-readable measurements and geometry, which is required for our investigation. Curve of Spee and Wilson will be measured using reverse engineering. Reverse engineering is the practice of disassembling an object in order to discover how it functions. It is generally done to analyze and learn how something functions, although it is frequently used to copy or improve the end result. • The curve of Spee will be measured by creating a tangent line connecting distobuccal cusp of mandibular 2 nd molars and highest tip of the mandibular incisors in a sagittal section. Measurements will be taken from that tangent line to the deepest point on the premolar region ( Figure 1 ). 6 • Frontal sections will be cut in the area of centre of 1 st molar. We shall follow the axis of molar, which follows a line that connects molars’ furcation and occlusal groove, to measure the Wilson curve’s angle. The greatest protuberance of the soft tissues present on buccal alveolar crest, the WALA points on the right and left bones, will be used to form a reference line. We can use it to calculate the angle between the left and right molars. The total angulation will be the sum of θ 1 and θ 2 ( Figure 2 ). 5 Figure 1. Curve of Spee will be taken from that tangent line to the deepest point on the premolar region. Figure 2. With WALA point used as a reference line Curve of Wilson will be measured. Outcomes To obtain a functional occlusion, it is essential to identify the patient’s dental arch form before the procedure and to apply mechanics that conform with the arch form throughout the therapy. Sample size Formula for sample size when comparing two means N = Zα + Zβ 2 δ 1 2 + δ 2 2 / k Δ 2 Where; Z α represents the degree of significance at 5% i.e., 95% Confidence interval = 1.96 Z β is the test’s power = 80% = 0.84 δ 1 = SD of COS depth in Class I = 0.717 δ 2 = SD of COS depth in Class II = 0.732 ∆ = Distiction between two means = 2.472 – 1.954 = 0.518 n = 1.96 + 0.84 2 0.717 2 + 0.732 2 / 1 0.518 2 = 30.67 n = 30 patients needed in each group Total sample size is 120 Study Reference: IIknur Veli et al . 7 Statistical method All the results will be calculated using R version 4.2.3 (Shortstop Beagle ) . Data for outcome variables will be tested for normality using Kalmogorov-Smirlov. Comparative analysis over the outcome of functional occlusion in different malocclusion will be evaluated and measurement of depth of curve of Spee and Wilson in millimeters respectively. ANOVA will be used to find significant difference in mean in comparison of 4 groups. Tukey test will be used for comparative evaluation of measurement in between 2 groups pairwise. P-value ≤ .05 will be considered significant 5% level of significance and 95% confidence of interval. The results and measurements will be evaluated by experienced technical engineers for Inter-rater reliability test to check the consistency of result obtained. Dissemination This protocol will assist us in evaluating and comparing the Spee and Wilson curves in Class II Div-1, Class II Div-2, & Class III malocclusions as against Class-I malocclusions, & this will help us design our treatments in order to avoid periodontal issues, ensure stability, and achieve effective occlusion. Study status Not started yet. Discussion Dentists may use Spee curve analysis to predict how the occlusion will develop in the sagittal plane. The inclination of the masseter muscle was positively correlated with the Spee curve. The placement of the mandibular posterior teeth with this forward tilt increases the efficacy of the chewing muscles. In Wilson curve, the posterior teeth’s inclination is caused by two factors. The first has to do with loading resistance, and the second, with masticatory function. 8 Several of the compensatory curves have been linked to normal occlusion and dentoskeletal malocclusions in literature before our study. A few studies have looked at the relationship between the Curves of Spee and Wilson, their impact on dentition, and their capacity to preserve stability of occlusion. This study explores the relationship between compensatory curves and how it might help in formulating treatment regimens for particular malocclusions. Ethical considerations Ethical approval received from Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha IEC reference number - DMIHER (DU)/IEC/2023/569 Data availability No source data are associated with this article. Extended data Zenodo. Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in class II div-1, class II div-2, and class III as against class-I malocclusion in central India population- an in vitro study. DOI: 10.5281/zenodo.7816557 . 9 File Name: SPIRIT_checklist RUCHIKA.docx Data are available under the terms of the Creative Commons Attribution 4.0 International license (CC-BY 4.0). Acknowledgements I would like to thank my institute and my colleagues. References 1. Dindaroğlu F, Duran GS, Tekeli A, et al. : Evaluation of the Relationship between Curve of Spee, WALA-FA Distance and Curve of Wilson in Normal Occlusion. Turk. J. Orthod. 2016 Dec; 29 (4): 91–97. PubMed Abstract | Publisher Full Text 2. Yang B, Chung CH: Buccolingual inclination of molars in untreated children and adults: A cone beam computed tomography study. Angle Orthod. 2019 Jan; 89 (1): 87–92. PubMed Abstract | Publisher Full Text | Free Full Text 3. Kumar KPS, Tamizharasi S: Significance of curve of Spee: An orthodontic review. J. Pharm. Bioallied Sci. 2012 Aug; 4 (Suppl 2): S323–S328. PubMed Abstract | Publisher Full Text 4. Dhiman S: Curve of Spee - from orthodontic perspective. Indian J. Dent. 2015; 6 (4): 199–202. PubMed Abstract | Publisher Full Text | Free Full Text 5. Barrera JM, Llamas JM, Espinar E, et al. : Wilson maxillary curve analyzed by CBCT. A study on normocclusion and malocclusion individuals. Med. Oral Patol. Oral Cir. Bucal. 2013 May 1; 18 (3): e547–e552. Publisher Full Text 6. Babu KS, Kumar AN, Kommi PB, et al. : Evaluating the correlation between anteroposterior and mediolateral compensatory curves and their influence on dentoskeletal morphology-an in vitro CBCT study. J. Clin. Diagn. Res. 2017; 11 (8): ZC49–ZC52. PubMed Abstract | Publisher Full Text 7. Veli I, Ozturk MA, Uysal T: Curve of Spee and its relationship to vertical eruption of teeth among different malocclusion groups. Am. J. Orthod. Dentofacial. Orthop. 2015 Mar; 147 (3): 305–312. PubMed Abstract | Publisher Full Text 8. Al-Qawasmi R, Coe C: Genetic influence on the curves of occlusion in children seeking orthodontic treatment. Int. Orthod. 2021 Mar; 19 (1): 82–87. PubMed Abstract | Publisher Full Text 9. Ruchika P, Ranjit K: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an In Vitro study. Zenodo. 2023. Publisher Full Text Comments on this article Comments (0) Version 3 VERSION 3 PUBLISHED 15 May 2023 ADD YOUR COMMENT Comment Author details Author details 1 Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India 2 Professor, Orthodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India Ruchika Pandey Roles: Conceptualization, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Ranjit Kamble Roles: Supervision, Validation Competing interests No competing interests were disclosed. Grant information The author(s) declared that no grants were involved in supporting this work. Article Versions (3) version 3 Revised Published: 10 Jul 2024, 12:493 https://doi.org/10.12688/f1000research.133330.3 version 2 Revised Published: 22 Apr 2024, 12:493 https://doi.org/10.12688/f1000research.133330.2 version 1 Published: 15 May 2023, 12:493 https://doi.org/10.12688/f1000research.133330.1 Copyright © 2024 Pandey R and Kamble R. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Download Export To Sciwheel Bibtex EndNote ProCite Ref. Manager (RIS) Sente metrics Views Downloads F1000Research - - PubMed Central info_outline Data from PMC are received and updated monthly. - - Citations open_in_new 0 open_in_new 0 open_in_new SEE MORE DETAILS CITE how to cite this article Pandey R and Kamble R. Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.12688/f1000research.133330.3 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS track receive updates on this article Track an article to receive email alerts on any updates to this article. TRACK THIS ARTICLE Share Open Peer Review Current Reviewer Status: ? Key to Reviewer Statuses VIEW HIDE Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Version 3 VERSION 3 PUBLISHED 10 Jul 2024 Revised Views 0 Cite How to cite this report: Maltagliati LÁ. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.168751.r301317 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v3#referee-response-301317 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 13 Jul 2024 Liliana Ávila Maltagliati , Guarulhos University, São Paulo, Brazil Not Approved VIEWS 0 https://doi.org/10.5256/f1000research.168751.r301317 This article aims to compare the curve of Spee and Wilson's characteristics between Class I, Class II division 1 and 2, and Class III. The method used to measure the curve of Spee is appropriate and aligns with the literature. ... Continue reading READ ALL This article aims to compare the curve of Spee and Wilson's characteristics between Class I, Class II division 1 and 2, and Class III. The method used to measure the curve of Spee is appropriate and aligns with the literature. However, as mentioned in the initial review, measuring the curve of Wilson is prone to errors since the furcation of molars is not detectable on cast models. Therefore, I recommend changing the methodology to analyze the curve of Wilson in a manner consistent with its original definition by the author, like the methodology used by Dindaroglu, the reference number 1. It is also important to correct the type of study described. This is not an in vitro study; it is clinical in nature, involving participants (patients) from whom impressions were taken. It is a cross-sectional study, and this should be clearly stated in both the title and the body of the text Competing Interests: No competing interests were disclosed. Reviewer Expertise: With methodological adjustments, the research may be resubmitted I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Maltagliati LÁ. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.168751.r301317 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v3#referee-response-301317 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 2 VERSION 2 PUBLISHED 22 Apr 2024 Revised Views 0 Cite How to cite this report: Maltagliati LÁ. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r269001 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-269001 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 14 May 2024 Liliana Ávila Maltagliati , Guarulhos University, São Paulo, Brazil Not Approved VIEWS 0 https://doi.org/10.5256/f1000research.165137.r269001 This is a comparative study about curve of Spee and Curve of Wilson in malocclusion patients. It is unquestionable the importance of those curves to a healthy occlusion and it is interesting to determine if different malocclusions present different characteristics ... Continue reading READ ALL This is a comparative study about curve of Spee and Curve of Wilson in malocclusion patients. It is unquestionable the importance of those curves to a healthy occlusion and it is interesting to determine if different malocclusions present different characteristics to be included in the treatment correction planning. Nevertheless some issues seems incomplete and in my opinion need revision: 1. It was not clear if the group with class I malocclusion will be a control group or will be compared as a malocclusion group and so the research will have no control group. My question is based on the fact that class I occlusion not necessarily is a normal occlusion. Conceptually, class I is a malocclusion. 2. Considering item 1, it would be a lot more interesting to have a group of normal occlusion as control group and then study curve of spee and curve of wilson deviation from normal occlusion 3. The reference used to create methodology for curve of Wilson analysis use CBCT exams to achieve long axis of mandibular molar. Using cast models, it seems difficult to be sure about the exact localization of root furcation. I encourage authors to change curve of wilson determination methodology. Is the rationale for, and objectives of, the study clearly described? Partly Is the study design appropriate for the research question? Partly Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Not applicable Competing Interests: No competing interests were disclosed. Reviewer Expertise: With methodological adjustments, the research may be resubmitted I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Maltagliati LÁ. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r269001 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-269001 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 29 Jun 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 29 Jun 2024 Author Response Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. ... Continue reading Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. Yes, it would have been better to use Class 1 normal occlusion as a control group rather than Class 1 malocclusion, but because they are uncommon and every person with Class 1 molar relation will have some type of malocclusion, it would be easier to use Class 1 Malocclusion as a control group. 3. Yes, it will be difficult to find furcation in cast models, so it will be supported by OPG analysis, as performing CBCT on every patient will be costly and not available in every facility. Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. Yes, it would have been better to use Class 1 normal occlusion as a control group rather than Class 1 malocclusion, but because they are uncommon and every person with Class 1 molar relation will have some type of malocclusion, it would be easier to use Class 1 Malocclusion as a control group. 3. Yes, it will be difficult to find furcation in cast models, so it will be supported by OPG analysis, as performing CBCT on every patient will be costly and not available in every facility. Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 29 Jun 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 29 Jun 2024 Author Response Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. ... Continue reading Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. Yes, it would have been better to use Class 1 normal occlusion as a control group rather than Class 1 malocclusion, but because they are uncommon and every person with Class 1 molar relation will have some type of malocclusion, it would be easier to use Class 1 Malocclusion as a control group. 3. Yes, it will be difficult to find furcation in cast models, so it will be supported by OPG analysis, as performing CBCT on every patient will be costly and not available in every facility. Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. Yes, it would have been better to use Class 1 normal occlusion as a control group rather than Class 1 malocclusion, but because they are uncommon and every person with Class 1 molar relation will have some type of malocclusion, it would be easier to use Class 1 Malocclusion as a control group. 3. Yes, it will be difficult to find furcation in cast models, so it will be supported by OPG analysis, as performing CBCT on every patient will be costly and not available in every facility. Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Velandia Palacio LA. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r268428 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-268428 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 09 May 2024 Luz Andrea Velandia Palacio , CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia Approved VIEWS 0 https://doi.org/10.5256/f1000research.165137.r268428 The authors have addressed the suggestions made in the ... Continue reading READ ALL The authors have addressed the suggestions made in the first review properly; I have no further comments to add. Competing Interests: No competing interests were disclosed. Reviewer Expertise: Orthodontics and dentofacial orthopedics I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Velandia Palacio LA. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r268428 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-268428 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 1 VERSION 1 PUBLISHED 15 May 2023 Views 0 Cite How to cite this report: Shetty V and Rao D. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r236704 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-236704 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 27 Jun 2024 Vabitha Shetty , Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India Dinesh Rao , Peditric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India Approved VIEWS 0 https://doi.org/10.5256/f1000research.146309.r236704 An interesting study, especially useful in orthodontic rehabilitation of patients.Background, rationale and objectives are well written. The study protocol seems well thought about and structured. Sample size seems appropriate and satisfactory. Could the authors state the reasons they have chosen ... Continue reading READ ALL An interesting study, especially useful in orthodontic rehabilitation of patients.Background, rationale and objectives are well written. The study protocol seems well thought about and structured. Sample size seems appropriate and satisfactory. Could the authors state the reasons they have chosen the CAD CAM machine for analysis of cast ? What are the advantages? Is the rationale for, and objectives of, the study clearly described? Yes Is the study design appropriate for the research question? Yes Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: Sleep dentistry, preventive dentistry, cephalometric analysis We confirm that we have read this submission and believe that we have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Shetty V and Rao D. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r236704 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-236704 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 27 Jun 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 27 Jun 2024 Author Response Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an ... Continue reading Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. Also, ma'am, we are employing the best CAD-CAM equipment, Dentsply Sirona. It has the essential feature of allowing you to work on machine-readable measurements and geometry, which is required for our investigation. Furthermore, it is highly precise, simple to copy, change, and annotate, and can be sent directly to milling for automated production. I can also send the STL file so that competent technical engineers can review the results and measurements. Thankyou Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. Also, ma'am, we are employing the best CAD-CAM equipment, Dentsply Sirona. It has the essential feature of allowing you to work on machine-readable measurements and geometry, which is required for our investigation. Furthermore, it is highly precise, simple to copy, change, and annotate, and can be sent directly to milling for automated production. I can also send the STL file so that competent technical engineers can review the results and measurements. Thankyou Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 27 Jun 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 27 Jun 2024 Author Response Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an ... Continue reading Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. Also, ma'am, we are employing the best CAD-CAM equipment, Dentsply Sirona. It has the essential feature of allowing you to work on machine-readable measurements and geometry, which is required for our investigation. Furthermore, it is highly precise, simple to copy, change, and annotate, and can be sent directly to milling for automated production. I can also send the STL file so that competent technical engineers can review the results and measurements. Thankyou Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. Also, ma'am, we are employing the best CAD-CAM equipment, Dentsply Sirona. It has the essential feature of allowing you to work on machine-readable measurements and geometry, which is required for our investigation. Furthermore, it is highly precise, simple to copy, change, and annotate, and can be sent directly to milling for automated production. I can also send the STL file so that competent technical engineers can review the results and measurements. Thankyou Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Velandia Palacio LA. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r255515 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-255515 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 01 Apr 2024 Luz Andrea Velandia Palacio , CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.146309.r255515 The article underscores the significance of the Curve of Spee (COS) and Curve of Wilson (COW) in relation to occlusion and mastication, as well as their biomechanical functions. It further explores the correlation between these curves and dental malocclusions, their ... Continue reading READ ALL The article underscores the significance of the Curve of Spee (COS) and Curve of Wilson (COW) in relation to occlusion and mastication, as well as their biomechanical functions. It further explores the correlation between these curves and dental malocclusions, their influence on treatment planning, and their connection to dentoskeletal morphology and occlusal stability. The aim of the study is to investigate the connection between compensatory curves and how it might aid in the development of treatment plans for specific malocclusions . I would like to point out the following in my review of this manuscript: The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct. Is the rationale for, and objectives of, the study clearly described? Partly Is the study design appropriate for the research question? Yes Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Not applicable References 1. Bearn D: Orthodontics and Dentofacial Orthopedics. J Orthod . 2002; 29 (2): 154 PubMed Abstract | Publisher Full Text Competing Interests: No competing interests were disclosed. Reviewer Expertise: Orthodontics and dentofacial orthopedics I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Velandia Palacio LA. Reviewer Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r255515 ) The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-255515 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 29 Apr 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 29 Apr 2024 Author Response Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and ... Continue reading Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. Response - I have done the necessary changes. 2. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Response -I have specified about interrater reliability test. 3.Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. Response - Regarding the lack of a direct 3-D scan of the patient, scanning intraorally will provide a more accurate result, however due to the unavailability of an intraoral scanner in our location, we will have to scan the cast instead. We will do our best to eliminate distortion while taking and pouring the impression cast. 4.In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct.​​​​​​​ Response - I have done the correction. Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. Response - I have done the necessary changes. 2. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Response -I have specified about interrater reliability test. 3.Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. Response - Regarding the lack of a direct 3-D scan of the patient, scanning intraorally will provide a more accurate result, however due to the unavailability of an intraoral scanner in our location, we will have to scan the cast instead. We will do our best to eliminate distortion while taking and pouring the impression cast. 4.In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct.​​​​​​​ Response - I have done the correction. Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 29 Apr 2024 Ruchika Pandey , Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India 29 Apr 2024 Author Response Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and ... Continue reading Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. Response - I have done the necessary changes. 2. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Response -I have specified about interrater reliability test. 3.Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. Response - Regarding the lack of a direct 3-D scan of the patient, scanning intraorally will provide a more accurate result, however due to the unavailability of an intraoral scanner in our location, we will have to scan the cast instead. We will do our best to eliminate distortion while taking and pouring the impression cast. 4.In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct.​​​​​​​ Response - I have done the correction. Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. Response - I have done the necessary changes. 2. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Response -I have specified about interrater reliability test. 3.Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. Response - Regarding the lack of a direct 3-D scan of the patient, scanning intraorally will provide a more accurate result, however due to the unavailability of an intraoral scanner in our location, we will have to scan the cast instead. We will do our best to eliminate distortion while taking and pouring the impression cast. 4.In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct.​​​​​​​ Response - I have done the correction. Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Comments on this article Comments (0) Version 3 VERSION 3 PUBLISHED 15 May 2023 ADD YOUR COMMENT Comment keyboard_arrow_left keyboard_arrow_right Open Peer Review Reviewer Status info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Reviewer Reports Invited Reviewers 1 2 3 Version 3 (revision) 10 Jul 24 read Version 2 (revision) 22 Apr 24 read read Version 1 15 May 23 read read Luz Andrea Velandia Palacio , CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia Liliana Ávila Maltagliati , Guarulhos University, São Paulo, Brazil Vabitha Shetty , AB Shetty Memorial Institute of Dental Sciences, Mangalore, India Dinesh Rao , AB Shetty Memorial Institute of Dental Sciences, Mangalore, India Comments on this article All Comments (0) Add a comment Sign up for content alerts Sign Up You are now signed up to receive this alert Browse by related subjects keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Maltagliati L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 13 Jul 2024 | for Version 3 Liliana Ávila Maltagliati , Guarulhos University, São Paulo, Brazil 0 Views copyright © 2024 Maltagliati L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Not Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions This article aims to compare the curve of Spee and Wilson's characteristics between Class I, Class II division 1 and 2, and Class III. The method used to measure the curve of Spee is appropriate and aligns with the literature. However, as mentioned in the initial review, measuring the curve of Wilson is prone to errors since the furcation of molars is not detectable on cast models. Therefore, I recommend changing the methodology to analyze the curve of Wilson in a manner consistent with its original definition by the author, like the methodology used by Dindaroglu, the reference number 1. It is also important to correct the type of study described. This is not an in vitro study; it is clinical in nature, involving participants (patients) from whom impressions were taken. It is a cross-sectional study, and this should be clearly stated in both the title and the body of the text Competing Interests No competing interests were disclosed. Reviewer Expertise With methodological adjustments, the research may be resubmitted I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. reply Respond to this report Responses (0) Maltagliati LÁ. Peer Review Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.168751.r301317) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/12-493/v3#referee-response-301317 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Maltagliati L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 14 May 2024 | for Version 2 Liliana Ávila Maltagliati , Guarulhos University, São Paulo, Brazil 0 Views copyright © 2024 Maltagliati L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Not Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions This is a comparative study about curve of Spee and Curve of Wilson in malocclusion patients. It is unquestionable the importance of those curves to a healthy occlusion and it is interesting to determine if different malocclusions present different characteristics to be included in the treatment correction planning. Nevertheless some issues seems incomplete and in my opinion need revision: 1. It was not clear if the group with class I malocclusion will be a control group or will be compared as a malocclusion group and so the research will have no control group. My question is based on the fact that class I occlusion not necessarily is a normal occlusion. Conceptually, class I is a malocclusion. 2. Considering item 1, it would be a lot more interesting to have a group of normal occlusion as control group and then study curve of spee and curve of wilson deviation from normal occlusion 3. The reference used to create methodology for curve of Wilson analysis use CBCT exams to achieve long axis of mandibular molar. Using cast models, it seems difficult to be sure about the exact localization of root furcation. I encourage authors to change curve of wilson determination methodology. Is the rationale for, and objectives of, the study clearly described? Partly Is the study design appropriate for the research question? Partly Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Not applicable Competing Interests No competing interests were disclosed. Reviewer Expertise With methodological adjustments, the research may be resubmitted I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. reply Respond to this report Responses (1) Author Response 29 Jun 2024 Ruchika Pandey, Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India Thank you for thoroughly analyzing my article. 1. It is apparent from the title and objective of this protocol that Class 1 malocclusion is used as the control group. 2. Yes, it would have been better to use Class 1 normal occlusion as a control group rather than Class 1 malocclusion, but because they are uncommon and every person with Class 1 molar relation will have some type of malocclusion, it would be easier to use Class 1 Malocclusion as a control group. 3. Yes, it will be difficult to find furcation in cast models, so it will be supported by OPG analysis, as performing CBCT on every patient will be costly and not available in every facility. View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Maltagliati LÁ. Peer Review Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r269001) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-269001 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Velandia Palacio L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 09 May 2024 | for Version 2 Luz Andrea Velandia Palacio , CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia 0 Views copyright © 2024 Velandia Palacio L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The authors have addressed the suggestions made in the first review properly; I have no further comments to add. Competing Interests No competing interests were disclosed. Reviewer Expertise Orthodontics and dentofacial orthopedics I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (0) Velandia Palacio LA. Peer Review Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.165137.r268428) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/12-493/v2#referee-response-268428 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Shetty V et al. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 27 Jun 2024 | for Version 1 Vabitha Shetty , Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India Dinesh Rao , Peditric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India 0 Views copyright © 2024 Shetty V et al. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions An interesting study, especially useful in orthodontic rehabilitation of patients.Background, rationale and objectives are well written. The study protocol seems well thought about and structured. Sample size seems appropriate and satisfactory. Could the authors state the reasons they have chosen the CAD CAM machine for analysis of cast ? What are the advantages? Is the rationale for, and objectives of, the study clearly described? Yes Is the study design appropriate for the research question? Yes Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise Sleep dentistry, preventive dentistry, cephalometric analysis We confirm that we have read this submission and believe that we have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (1) Author Response 27 Jun 2024 Ruchika Pandey, Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India Thankyou Ma'am for thorough analysis of my article. Ma'am I am well aware that direct 3-D scanning intraorally produces a more precise result; however, due to the lack of an intraoral scanner in our location, we will have to scan the cast instead. Also, ma'am, we are employing the best CAD-CAM equipment, Dentsply Sirona. It has the essential feature of allowing you to work on machine-readable measurements and geometry, which is required for our investigation. Furthermore, it is highly precise, simple to copy, change, and annotate, and can be sent directly to milling for automated production. I can also send the STL file so that competent technical engineers can review the results and measurements. Thankyou View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Shetty V and Rao D. Peer Review Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r236704) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-236704 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Velandia Palacio L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 01 Apr 2024 | for Version 1 Luz Andrea Velandia Palacio , CICO, Institución Universitaria Colegios de Colombia UNICOC, Bogotá, Colombia 0 Views copyright © 2024 Velandia Palacio L. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The article underscores the significance of the Curve of Spee (COS) and Curve of Wilson (COW) in relation to occlusion and mastication, as well as their biomechanical functions. It further explores the correlation between these curves and dental malocclusions, their influence on treatment planning, and their connection to dentoskeletal morphology and occlusal stability. The aim of the study is to investigate the connection between compensatory curves and how it might aid in the development of treatment plans for specific malocclusions . I would like to point out the following in my review of this manuscript: The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct. Is the rationale for, and objectives of, the study clearly described? Partly Is the study design appropriate for the research question? Yes Are sufficient details of the methods provided to allow replication by others? Yes Are the datasets clearly presented in a useable and accessible format? Not applicable References 1. Bearn D: Orthodontics and Dentofacial Orthopedics. J Orthod . 2002; 29 (2): 154 PubMed Abstract | Publisher Full Text Competing Interests No competing interests were disclosed. Reviewer Expertise Orthodontics and dentofacial orthopedics I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (1) Author Response 29 Apr 2024 Ruchika Pandey, Postgraduate, Orthodontics, , Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, 442001, India Thankyou sir for your thorough analysis of my article. I have made the following changes based on your review. 1. The objectives are “to evaluate the curve of Spee and the curve of Wilson in Class II Div.-1, Class II Div.-2, and Class-III malocclusion in the central Indian population. To evaluate the curve of Spee and the curve of Wilson in Class-I malocclusion in the central Indian population.” corresponds to the steps followed in the procedure of the study, not the aims of the study. Perhaps it would be better to state that the study will identify the relationship between the Spee curve and the Wilson curve for each malocclusion type. Response - I have done the necessary changes. 2. It is not clear if the measurements will be done by one or more observers; if so, it should be specified that an interrater reliability test will be performed and information regarding the observers experience in the field. Response -I have specified about interrater reliability test. 3.Explain the lack of a direct 3D scan of the patients, and keep in mind the differences in accuracy between direct scanning and cast model scanning. Response - Regarding the lack of a direct 3-D scan of the patient, scanning intraorally will provide a more accurate result, however due to the unavailability of an intraoral scanner in our location, we will have to scan the cast instead. We will do our best to eliminate distortion while taking and pouring the impression cast. 4.In the Introduction section, where there is the following statement:” The occlusal plane should be flattened and the Wilson curve should be levelled as the end results of orthodontic herapy," reference number 2 is used incorrectly. The author who made that original statement corresponds to [1] Please correct.​​​​​​​ Response - I have done the correction. View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Velandia Palacio LA. Peer Review Report For: Comparative evaluation and co-relation in variation of curve of Spee and curve of Wilson in Class II div. 1, Class II div. 2, and Class III as against Class I malocclusion in central India population- an in vitro study [version 3; peer review: 2 approved, 1 not approved] . F1000Research 2024, 12 :493 ( https://doi.org/10.5256/f1000research.146309.r255515) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/12-493/v1#referee-response-255515 Alongside their report, reviewers assign a status to the article: Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions Adjust parameters to alter display View on desktop for interactive features Includes Interactive Elements View on desktop for interactive features Competing Interests Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality. 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