Application of three HPV nucleic acid test reagents in the screening of high-risk HPV infection

not-yet-known not-yet-known not-yet-known unknown Objective To analyze the positive detection rate of three HPV reagents for 14 hr-HPV types. To provide more accurate medical evidence for the diagnosis of clinical HPV infection. Methods Three HPV reagents were used to detect HPV typing in the cervical exhaled cells of 678 patients with HPV infection, to compare the consistency between the detection results and the Sanger sequencing results, then to analyze the sensitivity and specificity of three detection reagents for 14 hr-HPV. Results Sensitivity of three HPV nucleic acid detection reagents: Reagent 1 (58.86%) P<0.001). For HPV16, 18, 31, 39, 52, 56, 66, and 68, there was a statistically significant difference in the positive rates of the three HPV nucleic acid testing reagents ( P<0.05) Conclusion For HPV 16, 31, 33, 39, 66 and 68, reagent 2 should be used for screening first, for HPV18, 52, reagent 1 should be used for screening first, reagent 3 should be used finally to recheck and detect the specifics to ensure the accuracy and sensitivity of the results.