Higher Pregnancy Rates Following Treatment of Cervical Factor with Intrauterine Insemination Without Superovulation Versus Intercourse: The Importance of a Well-Timed Postcoital Test for Infertility

Jerome H. Check, Paolo Spirito
In: Archives of Andrology · 1995 · vol. 35(1) , pp. 71–77 · doi:10.3109/01485019508987856 · PMID:8554435 · W2036982608
article OA: closed CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

Timed intrauterine insemination without hyperstimulation significantly increased pregnancy rates compared to intercourse for women with cervical factor infertility and a poor postcoital test.

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Abstract

A randomized study comparing the efficacy of timed intrauterine insemination (IUI) without hyperstimulation to sexual intercourse was performed in women with cervical factor infertility. Among the strict requirements for inclusion in the study were a normal semen analysis in the male partner, as well as the failure to demonstrate any sperm with progressive forward motion in a postcoital test performed 8-12 h after intercourse at the time of a mature follicle. All other infertility factors were negative. The data demonstrated a statistically significant fecundity rate at 1 month when IUI was compared to intercourse (21.2 vs. 3.9%). These data suggest that carefully timed IUI in nonhyperstimulated cycles is an effective treatment for cervical factor infertility.

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infertility

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