Ovarian cancer in infertility patients

Burmeister L, L Burmeister, Lynette Burmeister, David Healy, D L Healy, Healy DL
Annals of medicine · 1998 · vol. 30(6) , pp. 525–528 · doi:10.3109/07853899809002599 · PMID:9920353 · W2132457626
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This review discusses the unproven link between ovulation induction and ovarian cancer, noting that while infertility and endometriosis are potential independent risk factors, large prospective trials are needed to clarify the association.

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Abstract

The possibility that ovulation induction increases the risk of ovarian cancer remains unproven. However, recent studies suggest that both infertility and endometriosis may be independent risk factors. Despite the various case reports and epidemiological studies performed the association between the use of infertility drugs and ovarian cancer remains weak. The fact that the women who were the first to use ovulation agents are now reaching mid-life means that future studies should show whether any association exists. Hence, there is a need now for large prospective trials to be performed to establish whether an association between ovulation induction agents and ovarian cancer truly exists.

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Condition tags

endometriosisinfertility

MeSH descriptors

Infertility, Female Infertility, Female Infertility, Female Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms Adult Endometriosis Endometriosis Endometriosis Female Fertility Agents, Female Fertility Agents, Female Humans Middle Aged Ovulation Induction Ovulation Induction Risk Factors

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