Endometriosis as a comorbidity in pregnant patients with systemic lupus erythematosus: comment on the article by Nguyen et al

Maria I Zervou, George N. Goulielmos
Arthritis & rheumatology (Hoboken, N.J.) · 2026 · doi:10.1002/art.70155 · PMID:41879000
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This paper comments on an article by Nguyen et al. regarding the comorbidity of endometriosis in pregnant patients with systemic lupus erythematosus.

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This article by Zervou and Goulielmos is a commentary on a prior nationwide study by Nguyen et al examining temporal trends in adverse pregnancy outcomes and treatments among pregnant patients with systemic lupus erythematosus in Sweden. The authors focus on comorbid endometriosis in the context of SLE pregnancy, drawing attention to evidence that SLE is associated with an increased frequency of diagnosed endometriosis (citing population-based cohort work) and that endometriosis has been studied in relation to adverse pregnancy outcomes in other nationwide datasets. A key limitation of the commentary format is that it does not present new patient-level analyses; it relies on interpretation of existing findings and their applicability to the clinical context discussed by Nguyen et al. Relevance to endometriosis: the paper is centrally about endometriosis as a comorbidity in pregnant patients with systemic lupus erythematosus.

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Section of Molecular Pathology and Human Genetics Department of Internal Medicine, School of Medicine University of Crete and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece Section of Molecular Pathology and Human Genetics Department of Internal Medicine, School of Medicine University of Crete and Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece Zervou, M.I. and Goulielmos, G.N. (2026), Endometriosis as a comorbidity in pregnant patients with systemic lupus erythematosus: comment on the article by Nguyen et al. Arthritis Rheumatol. https://doi.org/10.1002/art.70155 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. References 1Nguyen NV, Sandström A, Dominicus A, et al. Nationwide temporal trends in adverse pregnancy outcomes and treatments in systemic lupus erythematosus pregnancy over two decades in Sweden. Arthritis Rheumatol Published online December 22, 2025. doi:10.1002/art.70018 2Abheiden CNH, Blomjous BS, Slaager C, et al. Systemic lupus erythematosus is associated with an increased frequency of spontaneous preterm births: systematic review and meta-analysis. Am J Obstet Gynecol2024; 231(4): 408–416.e21. doi:10.1016/j.ajog.2024.03.010 3Sun YH, Leong P-Y, Huang J-Y, et al. Increased risk of being diagnosed with endometriosis in patients with systemic lupus erythematosus: a population-based cohort study in Taiwan. Sci Rep2022; 12(1): 13336. doi:10.1038/s41598-022-17343-4 7Lim HJ, Sun J, Min B, et al. Endometriosis and adverse pregnancy outcomes: a nationwide population-based study. J Clin Med2023; 12(16):5392. doi:10.3390/jcm12165392 Total unique accesses to an article’s full text in HTML or PDF/ePDF format.More metric information Scite metrics Explore this article's citation statements on scite.ai Share QR Code Generating QR code QR code copied to clipboard! Something went wrong while generating your QR code. Please try again in a moment. If the issue persists, refresh the page or contact support. Export citation Unable to load citation data. Please try again in a moment. How to cite Elkins, L. J., & Spiegelman, M. (2021). pyUserCalc: A revised Jupyter notebook calculator for uranium-series disequilibria in basalts. Earth and Space Science, 8, e2020EA001619. https://doi.org/10.1029/2020EA001619 How to cite text copied to clipboard! Download Citation If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click on download. This feature enables you to download the bibliographic information (also called citation data, header data, or metadata) for the articles on our site. Citation manager file format Use the dropdown list to choose how to format the bibliographic data you're harvesting. Several citation manager formats are available, including EndNote and BibTex. You can then copy the formatted citation (as displayed) or download it as file, to your device. If the RefWorks format is chosen, the 'Download' button will be replaced with an option to directly export to RefWorks Please check your email for instructions on resetting your password. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. Request Username Can't sign in? Forgot your username? Enter your email address below and we will send you your username If the address matches an existing account you will receive an email with instructions to retrieve your username

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