Editorial: Highlights in abdominal and pelvic pain 2021/2022
This collection of articles highlights research in abdominal and pelvic pain, including non-pharmacological IBS treatments, probiotic effects on gut permeability and IBS symptoms, and a neuropathic-like component in endometriosis-associated pain.
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This editorial introduces a 2021/2022 Research Topic in Frontiers in Pain Research highlighting articles on mechanisms and therapies for abdominal and pelvic pain across multiple specialties, with examples including the brain-gut axis. It summarizes work on chronic visceral pain in irritable bowel syndrome, including evidence for cognitive behavioral therapy effects on stress-induced symptoms, mixed findings for acupuncture trials, and a randomized controlled trial where VSL#3 dosing was investigated with stool omics and metagenomic/ metabolomic measures, finding stool-identified probiotic organisms correlated with improved colonic permeability and clinical symptoms. The editorial also highlights a large questionnaire study reporting that endometriosis-associated pain may include a substantial neuropathic-like component, plus an IBS study linking episodic memories of symptom onset (often after GI infection) to greater symptom severity and worse health-related quality of life, while noting the memory specificity result was not different. This paper is centrally about endometriosis-associated pain as one of the highlighted topics—specifically whether endometriosis pain has a neuropathic-like component in a cohort questionnaire study.
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- europepmc
- last seen: 2026-09-20T09:27:46.357103+00:00
- pubmed
- last seen: 2026-09-24T06:09:42.247195+00:00
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