Editorial: Highlights in abdominal and pelvic pain 2021/2022

other OA: gold CC-BY-4.0
⚙ AI-generated summary by gemini-2.5-flash-lite+body, 2026-06-07 ⓘ

This collection of articles highlights research in abdominal and pelvic pain, including non-pharmacological IBS treatments, probiotic effects on gut permeability and IBS symptoms, and a neuropathic-like component in endometriosis-associated pain.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This editorial introduces a 2021/2022 Research Topic in Frontiers in Pain Research highlighting articles on mechanisms and therapies for abdominal and pelvic pain across multiple specialties, with examples including the brain-gut axis. It summarizes work on chronic visceral pain in irritable bowel syndrome, including evidence for cognitive behavioral therapy effects on stress-induced symptoms, mixed findings for acupuncture trials, and a randomized controlled trial where VSL#3 dosing was investigated with stool omics and metagenomic/ metabolomic measures, finding stool-identified probiotic organisms correlated with improved colonic permeability and clinical symptoms. The editorial also highlights a large questionnaire study reporting that endometriosis-associated pain may include a substantial neuropathic-like component, plus an IBS study linking episodic memories of symptom onset (often after GI infection) to greater symptom severity and worse health-related quality of life, while noting the memory specificity result was not different. This paper is centrally about endometriosis-associated pain as one of the highlighted topics—specifically whether endometriosis pain has a neuropathic-like component in a cohort questionnaire study.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 9,423 characters · extracted from oa-doi-fallback · 2 sections · click to expand

References

1. AnkersenDVWeimersPBennedsenMHaaberABFjordsideELBeberMEet alLong-term effects of a web-based LowFODMAP diet versus probiotic treatment for irritable bowel syndrome, including shotgun analyses of microbiota: randomized, double-crossover clinical trial. J Med Internet Res. (2021) 23(12):e30291. 10.2196/30291 2. NicolaMCorreiaH. Ditchburn G and drummond PD defining pain-validation: the importance of validation in reducing the stresses of chronic pain. Front Pain Res. (2022) 3:884335. 10.3389/fpain.2022.884335 3. WangJXiaQZhuFHuangWMengYWangYet alEffects of 92 acupuncture on adverse events in colonoscopy: a systematic review and metaanalysis of 93 randomized controlled trials. Pain Ther. (2022) 11:1095–112. 10.1007/s40122-022-00415-8 4. CaiHChengXWangXP. ATP7B Gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a mouse model of Wilson’s disease. Hepatology. (2022) 76:1046–57. 10.1002/hep.32484 5. DardiotisEKyriakidesT. Drug and gene therapy for treating variant transthyretin 98 amyloidosis (ATTRv) neuropathy. Curr Neuropharmacol. (2022). 10.2174/1570159X21666221108094736. [Online ahead of print] 6. WangXPLiuJMZhaoYB. Migraine: sex-influenced trait model?Med Hypotheses. (2008) 71:14–21. 10.1016/j.mehy.2007.12.01 Summary

Keywords

neuropathy, abdominal and pelvic pain, irritable bowel syndrome, acupuncture, VSL#3, endometriosis Citation Wang X-P and Wang B (2023) Editorial: Highlights in abdominal and pelvic pain 2021/2022. Front. Pain Res. 4:1097072. doi: 10.3389/fpain.2023.1097072 Received 13 November 2022 Accepted 31 January 2023 Published 16 February 2023 Volume 4 - 2023 Edited and reviewed by Julie A. Christianson, University of Kansas Medical Center, United States Updates Copyright © 2023 Wang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. *Correspondence: Xiao-Ping Wang [email protected] Specialty Section: This article was submitted to Abdominal and Pelvic Pain, a section of the journal Frontiers in Pain Research Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-09-20T09:27:46.357103+00:00
pubmed
last seen: 2026-09-24T06:09:42.247195+00:00
unpaywall
last seen: 2026-05-15T02:00:00.661756+00:00
License: CC-BY-4.0 · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine