Abhängigkeit zwischen ovarieller Suppression und Rückgang der Endometriose-Implantate bei LHRH-Analog(Buserelin)-Therapie

H. Ochs, U. Cirkel, Karl-Werner Schweppe, H. P. G. Schneider
In: Archives of Gynecology and Obstetrics · 1989 · vol. 245(1-4) , pp. 941–942 · doi:10.1007/bf02417630 · W4233055054
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This study investigated the relationship between ovarian suppression and the regression of endometriosis implants following treatment with the LHRH analog Buserelin.

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This brief paper examines the relationship between ovarian suppression and the regression of endometriosis implants during therapy with the LHRH analog buserelin. It is based on prior work in the endometriosis treatment literature and discusses an association between the degree of ovarian suppression achieved and the observed decrease in implant burden. The limitation is that the available text does not provide original patient-level methods, outcome measures, or statistical details within the paper itself. Relevance to endometriosis: the study directly concerns endometriosis implant regression in the context of LHRH-analog (buserelin)–induced ovarian suppression, making it centrally relevant to endometriosis.

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Literatur American Fertility Society (1979) Classification of endometriosis. Fertil Steril 32:633 Cirkel U, Schweppe K-W, Ochs H, Schneider HPG (1986) Effect of LH-RH agonist therapy in the treatment of endometriosis (German experience). In: Rolland R, Chadha DR, Willemsen WNP (eds) Gonadotropin Down-Regulation in Gynecological Practice. Alan R. Liss, New York, pp 189–199 Jänne O, Kauppila A, Kokko E, Lantto T, Rönnberg L, Vihko R (1981) Estrogen and progestin receptors in endometriotic lesions: Comparison with endometrial tissue. Am J Obstet Gynecol 141:562–566 Lemay A, Maheux R, Faure N, Jean C, Fazekas ATA (1984) Reversible hypogonadism induced by a luteinizing hormone releasing hormone (LH-RH) agonist (Buserelin) as a new therapeutic approach for endometriosis. Fertil Steril 41:863–871 Schweppe K-W, Wynn RM, Beller FK (1984) Ultrastructural comparison of endometriotic implants and eutopic endometrium. Am J Obstet Gynecol 148:1024–1030 Author information Authors and Affiliations Rights and permissions About this article Cite this article Ochs, H., Cirkel, U., Schweppe, K.W. et al. Abhängigkeit zwischen ovarieller Suppression und Rückgang der Endometriose-Implantate bei LHRH-Analog(Buserelin)-Therapie. Arch Gynecol Obstet 245, 941–942 (1989). https://doi.org/10.1007/BF02417630 Issue date: DOI: https://doi.org/10.1007/BF02417630

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