Influence on the ovarian reserves function after laparoscopic operation combined with GnRH on the women with ovarian endometrioma

Objective To discuss the influence on the ovarian reserves function after laparoscopic operation combined with gonadotropin-releasing hormone(GnRH) on the women with ovarian endometrioma.MethodsA total of 125 women with ovarian cyst,undergoing laparoscopic cystectomy were included.These patients were divided into five groups: 20 patients with unilateral teratoma(control),groups A(n=33,unilateral ovarian endometrioma,D≤5 cm),groups B(n=24,unilateral ovarian endometrioma,D5cm),groups C(n=27,bilateral ovarian endometrioma,D≤5 cm),groups D(n=21,bilateral ovarian endometrioma,at lest one side D5cm).Baseline levels of serum follicle stimulating hormone(FSH),luteinizing hormone(LH) and estrogen(E2) were in all cases before,six months and one years after operations,and the menses were observed one year after operation.ResultsIn the bilateral groups(C and D),the serum level of FSH increased significantly after the operation(P0.05),while E2 decreased significantly(P0.05),for LH decreased significantly(P0.05) one month after the operation.ConclusionIt suggested that ovarian reserve function would be decreased in laparoscopic bilateral ovarian endometrioma.And most patients recovered after one year,and the rate of natural pregnancy increased after the operation.Barrenness patients could increase the pregnancy rate after adding GnRH-a medicine based on the clinical staging.