Comprehensive Management of Endometriosis: Implementation from Research to Clinical Practice

Appendiceal endometriosis (AE) represents a clinically significant yet frequently overlooked manifestation of endometriosis that may contribute to persistent symptoms and suboptimal treatment outcomes. Multiple comprehensive reviews demonstrate that appendiceal involvement occurs in a notable percentage of women with endometriosis and can present with distinctive symptom patterns. Despite this growing body of evidence, routine appendiceal evaluation during surgical exploration for endometriosis remains inconsistently implemented across surgical practices. The failure to identify and treat AE may result in continued symptomatology despite otherwise successful endometriosis surgery, potentially necessitating additional interventions and compromising patient quality of life.