Polycystic Ovarian Syndrome and Endometriosis as Two Evil Extremes of Health Continuum

Mohammad Reza Sadeghi
Journal of reproduction & infertility · 2022 · vol. 23(1) , pp. 1–2 · doi:10.18502/jri.v23i1.8445 · PMID:36045878 · PMC9361725 · W4206919130
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-19 ⓘ

This paper reviews polycystic ovarian syndrome and endometriosis as potential manifestations of a shared underlying health continuum.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-27 · read from full text ⓘ

This commentary posits that polycystic ovarian syndrome and endometriosis represent opposing pathological extremes within a broader spectrum of female reproductive health disorders. The author argues that both conditions share common underlying mechanisms, particularly involving hormonal imbalances and inflammatory pathways, despite their differing clinical presentations. By framing these diseases as endpoints on a continuum, the paper highlights potential shared etiologies and therapeutic targets that could benefit patients suffering from either condition. This paper is centrally about endometriosis, using it as a key example to illustrate a theoretical model of disease progression alongside polycystic ovary syndrome.

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Abstract

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Publication Journal of Reproduction & Infertility Record type Journal article Published 23 January 2022 Authors Mohammad Reza Sadeghi The publisher of this work supports multiple resolution. The work is available from the following locations: {'doi': '10.18502/jri.v23i1.8445', 'member_id': '7770', 'member': 'Knowledge E DMCC', 'container-title': 'Journal of Reproduction & Infertility', 'primary-resource': 'https://publish.kne-publishing.com/index.php/JRI/article/view/8445', 'tld': 'kne-publishing.com', 'clearbit-logo': '/static/no_logo.svg', 'coaccess': [], 'multiple-resolution': [{'url': 'https://www.jri.ir/article/120145', 'tld': 'jri.ir', 'clearbit-logo': '/static/no_logo.svg'}, {'url': 'https://publish.kne-publishing.com/index.php/JHS/workflow/index/8218', 'tld': 'kne-publishing.com', 'clearbit-logo': '/static/no_logo.svg'}], 'type': 'JOURNAL ARTICLE', 'published_date': '23 January 2022', 'publication': 'Journal of Reproduction & Infertility', 'title': 'Polycystic Ovarian Syndrome and Endometriosis as Two Evil Extremes of Health Continuum', 'name': None, 'id': None, 'location': None, 'display_doi': 'https://doi.org/10.18502/jri.v23i1.8445', 'grant_info': None, 'grant_info_funders': None, 'grant_info_funder_ids': '', 'grant_info_type': None, 'multiple_lead_investigators': [], 'multiple_co_lead_investigators': [], 'multiple_investigators': [], 'finances': [], 'project_description': None, 'award_amount': None, 'award_start': None, 'funding_scheme': None, 'internal_award_number': None, 'editors': None, 'authors': 'Mohammad Reza Sadeghi', 'chairs': None, 'supplementary_ids': None} https://doi.org/10.18502/jri.v23i1.8445 JSON XML

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Condition tags

endometriosis

Citation neighborhood (sparse)

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References (5)

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License: CC0 · commercial use OK