Analysis of Antimicrobial Therapy and Pharmaceutical Care of Mixed Aspergillus and Mycobacterium tuberculosis Infection Following Renal Transplantation: a case report

Analysis of Antimicrobial Therapy and Pharmaceutical Care of Mixed Aspergillus and Mycobacterium tuberculosis Infection Following Renal Transplantation: a case report | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 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Data may be preliminary. 12 May 2026 V1 Latest version Share on Analysis of Antimicrobial Therapy and Pharmaceutical Care of Mixed Aspergillus and Mycobacterium tuberculosis Infection Following Renal Transplantation: a case report Authors : Jiao Zhang [email protected] , Yue Zhao [email protected] , Xin Zheng [email protected] , and Peng Yang [email protected] Authors Info & Affiliations https://doi.org/10.22541/authorea.15003207/v1 12 views 7 downloads Contents Abstract Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Invasive infection is a significant complication following renal transplantation. Due to long-term immunosuppressive therapy, renal transplant recipients are at high risk for fungal infections and tuberculosis, which are major causes of mortality . Triazole drugs, as first-line agents for invasive fungal infections, can cause fluctuations in the blood levels of immunosuppressants due to drug-drug interactions. Furthermore, the concomitant use of antituberculosis drugs complicates the balance between maintaining immunosuppression and anti-infective therapy, presenting a challenge to clinical decision-making. This article discusses the role of the clinical pharmacist in the treatment of a renal transplant recipient who developed concurrent pulmonary tuberculosis and aspergillus infection. By recommending initial antifungal and anti-tuberculosis regimens, implementing comprehensive medication monitoring, adjusting doses during outpatient follow-ups, and assessing and managing adverse drug reactions, the clinical pharmacist provided systematic pharmaceutical services. This collaboration assisted physicians in developing a personalized treatment plan, ultimately achieving favorable therapeutic outcomes. Information & Authors Information Version history V1 Version 1 12 May 2026 Collection British Journal of Pharmacology Authors Affiliations Jiao Zhang [email protected] Affiliated Hospital of Army Medical University, Chongqing, China View all articles by this author Yue Zhao [email protected] Affiliated Hospital of Army Medical University, Chongqing, China View all articles by this author Xin Zheng [email protected] Affiliated Hospital of Army Medical University, Chongqing, China View all articles by this author Peng Yang [email protected] Affiliated Hospital of Army Medical University, Chongqing, China View all articles by this author Metrics & Citations Metrics Article Usage 12 views 7 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Jiao Zhang, Yue Zhao, Xin Zheng, et al. Analysis of Antimicrobial Therapy and Pharmaceutical Care of Mixed Aspergillus and Mycobacterium tuberculosis Infection Following Renal Transplantation: a case report. 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