Beneficial effects of danazol on symptoms and laboratory changes in cholinergic urticaria

In: British Journal of Dermatology · 1987 · vol. 116(4) , pp. 553–556 · doi:10.1111/j.1365-2133.1987.tb05877.x · PMID:3555598 · W2070969637
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Danazol effectively reduced exercise-induced weals in cholinergic urticaria and significantly increased protease inhibitors, including antichymotrypsin.

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Abstract

In a double-blind placebo-controlled study, danazol, an attenuated androgen, was effective in reducing exercise-induced weals in cholinergic urticaria. Danazol treatment also caused significant elevations of several protease inhibitors, particularly antichymotrypsin which has been reported previously to be low in cholinergic urticaria.

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