Serum Calcium is Associated with Sudden Cardiac Arrest after Stroke: An Observational Multicenter Study of the eICU Database

The aim of our study was to investigate the association of serum calcium with sudden cardiac arrest (SCA) in patients with stroke. We evaluated the clinical data of 10226 acute stroke patients admitted to the intensive care unit. We assessed the correlation between serum calcium and SCA after acute stroke by multivariate logistic regression. A nonlinear association between platelet count and mortality of HS patients was investigated using a generalized additive model and smooth curve fitting. In this study, we found lower Serum Calcium at admission was associated with SCA of almost two times as high as that for that non-low calcium patients. An increment of per unit in serum calcium was associated with a 49% decrease in SCA. We found that the link between serum calcium at admission and SCA after stroke in the hospital was likewise nonlinear. In addition, we demonstrated that the inflection point of the serum calcium was 8.7 mg/dL. This study demonstrates a nonlinear relationship between serum calcium and the risk of SCA after stroke. Low serum calcium was a risk factor associated with in-hospital SCA after stroke, and elevated serum calcium may be a great intervention for decreasing the incidence of SCA after stroke.