Efficacy of intrauterine balloon stent or oral estrogen on prevention of adhesion after transcervical resection of septum in septate uterus: Study protocol for a randomized controlled multicenter study in China

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This paper outlines the protocol for a randomized controlled multicenter study in China to evaluate the efficacy of intrauterine balloon stents or oral estrogen in preventing adhesions after transcervical resection of septum in patients with septate uterus.

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This paper outlines the study protocol for a randomized controlled multicenter trial conducted in China to evaluate methods for preventing intrauterine adhesions following transcervical resection of a septate uterus. The research design compares the efficacy of an intrauterine balloon stent against oral estrogen therapy as postoperative interventions. While the text provided consists primarily of acknowledgments and funding information, it establishes the framework for assessing surgical outcomes in patients with uterine septum anomalies. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Funding

This study was supported by a grant from the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (NO. 2020-PT320-003).

Acknowledgements

We would like to thank the person to contact at each center (Jinghua Li, Haiyan Wang, Xiangdong Hua, Ruonan Xu, Yousheng Zhang, Yun Yang, Li Chen, Shasha Rao, Qiuhong Liu, Yaling Sun) for their contribution in implementation of this trial. We would like to thank Weijie Tian for his help in registering and applying working account. We would like to thank Haiqing Zhan and Jing Dong for their work in development and maintenance of the data input platform.

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MeSH descriptors

Septate Uterus Estrogens Female Humans Hysteroscopy Hysteroscopy Multicenter Studies as Topic Pregnancy Randomized Controlled Trials as Topic Tissue Adhesions Tissue Adhesions Tissue Adhesions Uterus Uterus

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europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
pubmed
last seen: 2026-10-08T21:42:03.417289+00:00
unpaywall
last seen: 2026-08-13T06:47:16.638238+00:00
License: CC-BY-NC-ND-4.0