Expression, regulation and function of MicroRNAs in endometriosis

Die Pharmazie · 2016 · vol. 71(8) , pp. 434–438 · doi:10.31083/ph.2016.5904 · PMID:29442029 · W3024286694
review OA: hybrid CC0 ⤵ 7 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-09

This review examines recent findings on the expression, regulation, and function of microRNAs in endometriosis, highlighting their potential as biomarkers and therapeutic targets.

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Abstract

Endometriosis (EMS), characterized by the presence and growth of functional en do met rial-like tissues outside the uterine cavity, is a common and benign gyneco logical disorder with a poorly understood and somewhat enigmatic etiopathogenesis and pathophysiology. MicroRNAs (miRNAs) are single-stranded 19-25 nucleotide-long RNAs and have an important role in post-transcriptional gene silencing by base pairing with target mRNAs. Recent research has shown that miRNAs and their target mRNAs are differentially expressed in endometriosis and other disorders of the female reproductive system. In this paper, we review the recent progress in understanding the roles of miRNAs in endometriosis, and specific miRNAs as biomarkers and therapeutic targets for endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis MicroRNAs Biomarkers Endometriosis Endometriosis Female Gene Expression Regulation Humans MicroRNAs MicroRNAs MicroRNAs RNA Interference

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:54.390225+00:00
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