A prospective study of Secondary Tracheoesophageal Puncture in Chinese Total Laryngectomy Patients

A prospective study of Secondary Tracheoesophageal Puncture in Chinese Total Laryngectomy Patients | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 20 May 2025 V1 Latest version Share on A prospective study of Secondary Tracheoesophageal Puncture in Chinese Total Laryngectomy Patients Authors : Duo Zhang 0000-0002-4054-5537 , Shuo Ding 0000-0002-9600-043X , Xiao-Feng Jin , Wu Ping , Ling Chen , Jian-Fang Wu , Yang Zhang , … Show All … , Wei Guo , Yan-Yan Niu , Hong Huo , Wei Gu , Jian Wang , Qi Zhong , and Lei Tao 0000-0003-3384-9396 [email protected] Show Fewer Authors Info & Affiliations https://doi.org/10.22541/au.174773725.59623740/v1 Published Acta Oto-Laryngologica Version of record Peer review timeline 161 views 75 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Purpose Tracheoesophageal speech (TES) with a voice prosthesis (VP) is considered standard care in many countries for voice rehabilitation after total laryngectomy. Until recently, VPs were not available in China, and therefore patients had to use other communication methods. The aim of this study was to evaluate the feasibility of secondary tracheoesophageal puncture (TEP) as well as the effectiveness of TES as a method of voice rehabilitation in Chinese-speaking individuals living in China. Materials and Methods This clinical study was designed as a multicenter prospective single arm study. Thirty-six laryngectomy patients were enrolled and underwent a secondary tracheoesophageal puncture with placement of a Provox Vega. Voice assessments (clinician rated, objective assessment, and patient reported) were performed prior to VP placement and after 24 weeks, and VPs were changed every 3 months. Voice rehabilitation success and complications were recorded. Clinical Trials.gov Identifier: NCT05482815. Results There was a statistically significant improvement in clinician rated perceptual speech assessment (fluency, speed, pitch, intelligibility) at 24 weeks after TEP compared to baseline scores prior to placement of a VP. Sound intensity was significantly higher after TEP compared to pre-TEP, however, no significant change in maximum phonation time was observed. Patient reported voice handicap index was significantly lower after TEP compared to baseline. At the end of the study, 81% of the participants (29/36) were considered to have achieved an effective voice. Conclusion TEP is a feasible and an effective communication option post-laryngectomy for patients in China. Supplementary Material File (secondary tep and vp implantation following tl _v7.docx) Download 521.79 KB Information & Authors Information Version history V1 Version 1 20 May 2025 Peer review timeline Published Acta Oto-Laryngologica Version of Record 24 Sep 2025 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Authors Affiliations Duo Zhang 0000-0002-4054-5537 Fudan University View all articles by this author Shuo Ding 0000-0002-9600-043X Beijing Tongren Hospital CMU View all articles by this author Xiao-Feng Jin Peking Union Medical College Hospital View all articles by this author Wu Ping Fudan University View all articles by this author Ling Chen Fudan University View all articles by this author Jian-Fang Wu Fudan University View all articles by this author Yang Zhang Beijing Tongren Hospital CMU View all articles by this author Wei Guo Beijing Tongren Hospital CMU View all articles by this author Yan-Yan Niu Peking Union Medical College Hospital View all articles by this author Hong Huo Peking Union Medical College Hospital View all articles by this author Wei Gu Peking Union Medical College Hospital View all articles by this author Jian Wang Peking Union Medical College Hospital View all articles by this author Qi Zhong Beijing Tongren Hospital CMU View all articles by this author Lei Tao 0000-0003-3384-9396 [email protected] Fudan University View all articles by this author Metrics & Citations Metrics Article Usage 161 views 75 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Duo Zhang, Shuo Ding, Xiao-Feng Jin, et al. A prospective study of Secondary Tracheoesophageal Puncture in Chinese Total Laryngectomy Patients. Authorea . 20 May 2025. DOI: https://doi.org/10.22541/au.174773725.59623740/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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