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Ede, Tara Kwakkernaat, Maud J. Verhoeven, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5849625/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Integrated care initiatives for socioeconomically vulnerable groups have the potential to deliver personalised care, enhance health outcomes, and foster greater equity within the healthcare system. However, the incorporation of these initiatives into standard care is rare. Insight into implementation barriers and facilitators to select strategies for further implementation and upscaling are therefore needed. Methods We conducted a case study on an integrated care initiative adopting interprofessional collaborative practice of patient-centred care for citizens with prediabetes in the form of group consultations. We used a qualitative design guided by the Consolidated Framework of Implementation Research (CFIR) in combination with the Rainbow Model of Integrated Care. Semi-structured interviews and a focus group were conducted among stakeholders, including health and social care professionals, policy makers, and experts by experience. We used Framework analysis to analyse the data. We matched implementation strategies to a selection of barriers using CFIR’s Expert Recommendations of Implementation Research matching tool. Results We conducted 28 interviews and one focus group (n = 16). Key barriers included insufficient involvement of citizens in the design of the group consultations, which could be overcome by involving patients/consumers and family members in the design of the group consultations. Additionally, we identified a lack of embedding in the current healthcare system and fragmentation of funding as barriers. By developing a formal implementation blueprint, obtaining formal commitments, using other payment schemes, and developing resource sharing agreements, these barriers could be addressed. Finally, inadequate evaluation was identified as a barrier. This could be improved by capturing and sharing local knowledge and developing and organising a quality monitoring system. Key facilitators were the widespread enthusiasm for the concept of group consultations, a sense of urgency for change, and the adaptability of the initiative to the local context. Conclusions Citizen involvement in the design of an integrated care initiative, such as group consultations, is a key determinant of implementation when targeting socioeconomically vulnerable groups. Further research is needed to explore payment options within or beyond the current siloed health and social systems. Implementation determinants socioeconomically vulnerable groups integrated care prediabetes local initiative bottom-up BACKGROUND The prevalence of prediabetes was found to be higher than previously estimated in the Netherlands, with approximately 21% of males and 15% of females between 40 and 75 years of age having prediabetes ( 1 ). Prediabetes is characterised by elevated blood glucose levels that are not yet high enough to be classified as diabetes ( 2 ). Around 70% of people with prediabetes develop type 2 diabetes within ten years ( 2 , 3 ). The deterioration from prediabetes to diabetes was found to be socially patterned, with socioeconomically vulnerable people having an increased risk of developing diabetes compared with their more affluent peers ( 4 ). As within the diabetes population, the prevalence of prediabetes is nearly double in the most deprived one-third of the population compared with the least deprived one-third of the population, with a prevalence of 27% and 15%, respectively ( 1 ). To prevent the deterioration from prediabetes to diabetes, lifestyle interventions have proven effective in restoring normal blood glucose levels and improving cardiometabolic markers ( 2 , 5 , 6 ). However, social-contextual constraints can hinder lifestyle changes if not properly addressed, for example individual characteristics including socioeconomic position and neighbourhood characteristics ( 7 , 8 ). This can place socioeconomically vulnerable people at a further disadvantage. Although initiatives are available to mitigate these social constraints, many citizens do not receive appropriate support matched to their needs because of fragmentation of the health and social care systems (unpublished findings). Across different contexts, there is growing recognition of the need to integrate social support and medical care. Health advocates emphasise its potential to deliver personalised care, enhance health outcomes, and foster greater equity within the healthcare system ( 7 , 9 , 10 ). Using an integrated care approach, underlying issues hindering lifestyle change, such as debt or unemployment, could be addressed first before the focus is shifted to stimulating lifestyle change ( 7 ). This approach has the potential to improve health especially in socioeconomically vulnerable people ( 10 ). Despite the promise of integrated care initiatives, the incorporation of these initiatives into standard care is rare ( 11 – 13 ). Previously identified barriers include difficulties in sharing information between professionals and/or organisations ( 12 , 14 – 17 ), funding ( 12 – 18 ), and the accessibility of locations ( 15 , 16 ). Facilitators include effective communication and collaboration between professionals ( 12 , 14 – 17 , 19 ). Facilitators identified when specifically targeting socioeconomically vulnerable groups include citizen engagement and needs assessment and the use of a positive health approach. From a positive health perspective, health encompasses more than just addressing disease and illness; it also involves an individual's perceived control and capacity to manage life's challenges ( 18 ). As for integrated care initiatives in general, funding has proven to be a barrier when this specific population is targeted ( 18 ). Information on whether the identified barriers and facilitators are similar when targeting socioeconomically vulnerable groups remains scarce, despite the potential benefits of integrated care for these groups ( 15 , 20 – 22 ). Therefore, we used group consultations that bridge the medical and social domain, targeting citizens with prediabetes living in socioeconomically vulnerable neighbourhoods in The Hague, the Netherlands, as a case example of an integrated care initiative. These group consultations are characterised by interprofessional collaborative practice of patient-centred care for individuals with prediabetes and were initially provided in two neighbourhoods in The Hague, The Netherlands. An implementation team of various professionals is now exploring upscaling to additional neighbourhoods. For this purpose, insights into implementation barriers and facilitators, as well as the selection of context-sensitive strategies for implementation and upscaling, are needed. Therefore, we aim to evaluate the implementation barriers and facilitators of this integrated care initiative which targets socioeconomically vulnerable groups and select strategies to improve implementation and upscaling. METHODS Study design and setting We conducted a case study using a qualitative design combining individual interviews and a focus group to evaluate barriers and facilitators of the implementation of an integrated care initiative that adopts interprofessional collaborative practice of patient-centred care for individuals with prediabetes in the form of group consultations ( 23 ). The group consultations were developed by a primary care physician motivated by her observations that some socioeconomically vulnerable people with prediabetes frequently returned to her practice with recurring physical complaints. These complaints often stem from unresolved underlying social constraints that remain unaddressed in traditional primary health care. She decided to adopt a Population Health Management approach ( 24 ) and use interprofessional collaborative practice to better adjust care to the multifaceted needs of this vulnerable group. She collaborated with a neighbourhood sports coach, a social worker, and medical staff to design a group consultation, aiming to familiarise citizens with available local support tailored to their needs. During a single 90-minute session, various professionals from different disciplines, including but not limited to a primary care physician, neighbourhood sports coach, and social worker, together provide a group consultation where the interrelatedness of social and medical problems is discussed from a positive health perspective ( 25 ) a physical check-up is conducted, and a warm handoff is arranged for initiatives in the neighbourhood on the basis of the social and medical needs of the participants. Follow-up trajectories could include sessions with the neighbourhood sports coach, a lifestyle coach, or social worker. A group follow-up session is provided six months after the initial session. The groups generally consisted of between four and 15 participants. These group consultations were initiated in two neighbourhoods in 2019, and in 2023 scaling commenced to additional neighbourhoods in The Hague. An implementation team, including health care professionals, community representatives, and researchers, was involved in the upscaling of the intervention. Theoretical frameworks and data collection We used the implementation determinant framework Consolidated Framework of Implementation Research (CFIR) in combination with the Rainbow Model of Integrated Care (RMIC) to guide data collection and analysis. The CFIR offers a standardised structure for identifying barriers and facilitators of implementation, enabling knowledge generation on what works where, beyond the specific research settings ( 26 ). This framework identifies six domains: innovation, the outer setting, the inner setting, individuals, and the implementation process; each domain is composed of a number of constructs ( 26 ). The RMIC was developed to better understand the concept of integrated care ( 27 ). The model conceptualises the process of integrating care through six dimensions: clinical, professional, organisational, system, functional, and normative integration ( 27 ). To deliver integrated care, integration across all levels is needed. The first four dimensions explore integration from the micro to the macro level. Clinical integration is defined as the coordination of patient care activities and whether services improve an individual’s overall well-being; professional integration explores the collaboration among healthcare professionals across disciplines; organisational integration analyses the alignment and cooperation among healthcare organisations; and system integration considers the broader health system's policies, regulations, and structures that influence care delivery ( 27 ). Functional integration supports and links integration over these four levels, and normative integration is defined as the development and maintenance of a shared mission, vision, values and culture over the four levels ( 27 ). We used the first four dimensions to guide participant selection and structure findings. We employed the CFIR’s Expert Recommendation for Implementing Change (ERIC) framework for the selection of implementation strategies matched to the identified barriers and facilitators ( 28 ). This framework defines implementation strategies based on input from a wide range of stakeholders ( 28 ). By using this framework, we ensured the unambiguous use of previously defined strategies. Data collection took place between April and October 2024 and is described in detail below. Interviews Semi-structured interviews guided by the CFIR framework were conducted with a varied group of stakeholders directly or indirectly involved in the organisation of the group consultations. The interviews were conducted in-person, via videocall or by telephone, depending on the preference of the interviewee. We used purposive sampling guided by the RMIC levels to select participants. Professional networks of implementation team members were used in this process. A priori the sample size to reach meaning saturation was estimated at approximately 26 interviews, as we expected partial overlap in barriers and facilitators over the four levels of the RMIC. Meaning saturation was reached when no new barriers or facilitators were identified nor refinement was needed ( 29 ). As CFIR includes a comprehensive list of constructs, a selection of topics was chosen prior to each interview based on the knowledge and expertise of the respondent. Additional constructs were discussed when deemed appropriate. The majority of interviews were conducted by JGtB, six together with a student (TK or MV) and three by a student alone (TK or MV). The interviews were recorded and transcribed verbatim. Focus group A semi-structured in-person focus group was organised with a women’s group of experts by experience volunteering in the neighbourhood. The group consisted of 16 women, 11 of whom had previously participated in a group consultation. The focus group provided further insights into barriers and facilitators at the clinical level of implementation and was used to validate and enrich findings from the individual interviews. The focus group was not recorded. Instead, field notes were made during the session and subsequently expanded by two authors (RCV and JGB) who were present during the discussion. This approach was found to be more appropriate because audio recording potentially changes the group dynamic as participants experience nervousness over their voices being recorded ( 30 ). Data analysis We used Framework analysis, a descriptive qualitative approach originating from policy research, to analyse the data obtained during interviews and the focus group ( 31 ). Framework analysis is a method to describe and interpret what is happening in a particular setting via five iterative steps: familiarization, identification of a thematic framework, indexing, charting, and mapping and interpretation ( 31 ). All steps were conducted by the first author (JGtB) in collaboration with a ‘critical friend’ ( 32 ), AFTME, and overseen by RCV. The five steps were discussed and revised during critical dialogue over several sessions. The dialogue provided a theoretical sounding board where the thought process of the first author was evaluated, alternative interpretations were coined, and interpretations were revised accordingly. A priori, the CFIR was identified as a suitable framework to guide data analysis. Based on the familiarisation phase, deductive use of CFIR domains and constructs for indexing was deemed appropriate. To enable further discussion of the indexing in a time-efficient manner, a step between indexing and charting was added. We first arranged the indexed data according to the CFIR constructs via a ‘cut and paste’ approach, after which adjustments to the indexing were made to reach consensus. A distilled summary per construct was then charted, ordered by the RMIC levels. We used mapping and interpretation to define barriers and facilitators per construct and RMIC level using the distilled summaries. This process was conducted iteratively until meaning saturation was reached. Then, related barriers and facilitators were combined by JGB and RCV and a selection was made to identify those most prominently needing strategies to overcome the barrier or leverage the facilitator. This process was evaluated by two members of the implementation team and an independent expert familiar with the intervention who were not involved in this study. We matched the implementation strategies to the selected barriers using CFIR’s ERIC matching tool ( 33 ). RESULTS We conducted 28 interviews and one focus group (n = 16). Four interviews and the focus group were with professionals operating at the clinical level of the RMIC, eight interviews at the professional level, nine at the organisational level, and seven at the system level. The interviewees included but were not limited to experts by experience, community leaders, medical and social care professionals, members of the expert team organising the group consultations and representatives of the municipality, health insurance and the government. We identified 50 unique barriers and 30 unique facilitators of the implementation of the group consultations (Additional file 1). Ten more determinants were identified; these determinants were present in some neighbourhoods and absent in others and functioned as facilitators when present and barriers when absent. From these 90 determinants, we selected five main barriers and three main facilitators (Table 1 ). Implementation strategies were identified for the main barriers. These barriers, facilitators, and strategies are further discussed below. Table 1 Selected barriers and facilitators, their CFIR determinant and level of RMIC, with an illustrative quote. Determinant Determinant CFIR Level of the RMIC Quotes Barriers Insufficient involvement of citizens in the design of the group consultations. Important sub barriers: - The examples used during the group consultations are not tailored to the cultural background of participants. - Detachment between residents and professionals reduces trust - Many citizens think it is important to have separate groups for men and for women Process - Assessing needs Innovation – Innovation design Outer setting – Local conditions Outer setting – Local attitudes Clinical, professional, and organisational Q1: “But it also has to do with: you put things in front of me that I don't like. You want me to cook certain things that I don't know how to cook.” – Clinical level Q2: “This is a theme about losing weight. Especially among women, it is a private theme. It's a... It also has to do with self-confidence, self-confidence. So in a group where there are men there, you're not really going to be able to get that out, so out of, that a woman is going to tell something so intimate.” – Clinical level Q3: “I also hope that the consultations will be carried even more by the local residents themselves, so that it really comes from the community. And that they also get a voice in designing the consultations, for example.” – Professional level Q4: “Adjusting [the intervention] to the group, there’s still a lot to be done in that, in my opinion” – Organisational level Gap between the group consultations and local follow-up initiatives Innovation – Innovation design Clinical, professional, and organisational Q5: “At this one there were lots of dieticians and someone from, for people with financial problems, for people with financial, you name it. All sorts of things were there. Eating problems.[...] Heart foundation was also there and I understood that all. Also understand why they were invited. I was only wondering like: what's the added value? The performance did go nicely. It was nice. The atmosphere and everything. That was all right. But after that I did notice some people were like: what am I here for? What is the actual help?” – Clinical level Q6: “Often they are in different trajectories and then it may occur that I lose track of them, but they are still actually working on a trajectory, which also originated from the group consultation. So that link, if indeed something is documented or streamlined, that we can also better keep track on that. [...] So often you lose the people who try something and it doesn't work out and then think: it didn't work out, I'll stop. Whereas a moment of contact or a signal of: this person has stopped, if we can pick this up again, it will be easier to pick up the trajectory again.” – Professional level The lack of embedding of the group consultation into formal agreements/structures. Important sub barrier: Roles within the implementation team are unclear. Process – Planning Individuals – Implementation leads Organisational and system Q7: “For that to spread out completely in the neighbourhoods, there is - I think - still a lot depending on enthusiastic colleagues - professionals - rolling that out. Ideally, you would like to secure that in a function within.... In a neighbourhood, for instance. That it is not person-dependent, but more embedded.” – Organisational level Fragmentation of funding Outer setting – Local conditions; Inner setting – Available resources Professional, organisational, and system Q8: “[…]funding is a problem and has been for some time, because on the one hand you have the angle from medical support and support from the social domain, with health insurer and municipality looking at each other like: who is going to pay for what?” – Organisational level Q9: “And yes, you know, I think this is actually another one of those typical annoying cases of the responsibility lies everywhere and therefore nowhere.” – System level Inadequate evaluation of effectiveness and the implementation process. Process – Reflecting and evaluating Professional, organisational, and system Q10: “Sure she asked that at some point. Sure that that also came up and I may have mentioned something. But not very well-founded and not very well thought out, I think.” – Professional level Q11: “But to put it very simply: to get a payment title for group consultations, you will have to present results from the field, if you would want to pay for it from the ZVW [Health Insurance Act].” – System level Facilitators Widespread enthusiasm for the concept of the group consultations Innovation – Innovation relative advantage Inner setting – Mission alignment Clinical, professional, organisational, and system level Q12: “During group consultations, we notice that people truly feel heard.” – Professional level Q13: “Well, if you go to one of those group consultations […] and you find out there: who is that dietician? Oh, […] that seems like a really nice person. And you can make an appointment right away, that’s of course perfect. Then you really have, just that warm referral.” – Organisational level Sense of urgency for change among stakeholders Inner setting – Tension for change Professional level Q14: “I said: well, I'm open to that kind of thing too, just offering care in a different way instead of just one-to-one. Because sometimes you think: ‘Hello, does it sink in?’ ‘Or what about the advice I give?’ And then when someone says, for example, after ten times, “I've never heard that before.” Then I think, I think I've already told them ten times.” – Professional level Adaptability of the initiative to the local context Innovation – Innovation adaptability Clinical, professional, and organisational level Q15: “Yes, because you see that that's important for success. That you respond to the needs in the neighbourhood” – Professional level Q16: “If there are a lot of questions regarding quitting smoking, then we'll grab that quit smoking coach again. So that way you can adjust it a little bit each time too.” – Professional level Table 1 : Selected barriers and facilitators, their CFIR determinant and level of RMIC, with an illustrative quote. Barriers The first main barrier was the insufficient involvement of citizens in the design of the group consultations, which was identified as being part of the ‘assessing needs’ determinant of the ‘process’ domain of CFIR. This barrier was identified at the clinical, professional, and organisational levels of the RMIC. The limited involvement of citizens in the design and implementation process resulted in several sub barriers, such as inadequate tailoring of the intervention to the cultural background of participants and reduced trust (Table 1 Quote (Q) 1–4). A second barrier was found at the clinical, professional, and organisational levels under ‘innovation design’ , which is part of the ‘innovation’ domain. The respondents reported that there remained a gap between the group consultations and local follow-up initiatives, such as sessions with the neighbourhood sports coach, a lifestyle coach, or social worker. Two distinct gaps were reported. The participants felt that they did not receive adequate information about the follow-up steps, thereby preventing the initiation of a follow-up trajectory (Table 1Q5). The professionals mentioned that when they lost touch with participants, they were unaware of whether these participants were still seen by other colleagues and thus “in the system” or fell off the professionals’ radar. Due to the lack of a structured feedback system, professionals felt demotivated to keep track of lost participants (Table 1Q6). The third barrier we identified was the lack of embedding of the group consultation into formal agreements/structures. This barrier was identified at the organisational and system levels as a determinant of ‘planning’ under the ‘process’ domain. Currently, the initiative relies on efforts from various enthusiastic professionals and partners that support continuation, as described later under facilitators. However, participants mentioned the importance of embedding the initiative into formal structures to safeguard sustainability and scaling regardless of enthusiastic professionals potentially switching positions or not being able to put in the same effort (Table 1Q7). Guaranteeing the sustainability of the initiative related to the fourth barrier: the fragmentation of funding. This determinant was identified at the professional, organisational, and system levels and categorised under both the ‘local conditions’ in the ‘outer setting’ and ‘available resources’ in the ‘inner setting’ . The respondents elaborated on the complexity of the Dutch health system, as healthcare and social support are regulated and funded according to two different laws with different paying parties, and the lack of formal responsibility for health and prevention. Interviewees explained that funding parties point fingers to each other to take initiative (Table 1Q8 and Q9). No sustainable funding agreements have been made yet, thereby causing the initiative to rely on temporary funding, which threatens sustainability. The last main barrier was inadequate evaluation of effectiveness and the implementation process. This barrier was identified at the professional, organisational, and system levels under the ‘reflecting and evaluating’ construct of the ‘process’ domain. This barrier was multifaceted. The interviewed professionals had different perceptions of whether the process is currently being monitored. While some described some sort of process evaluation and monitoring system, others mentioned not being included in this process (Table 1Q10). Overall, there seemed to be no clear structure in the process or effectiveness evaluation. The respondents also emphasised the difficulties associated with evaluating the effectiveness of preventative initiatives. They explained that not all participants change their behaviour right away; some might forget about it for some time and then after an additional trigger use the information received. Long-term evaluation is needed to capture these delayed effects. The respondents at the system level emphasised the importance of evaluating the effectiveness to secure sustainable funding (Table 1Q11). Facilitators The first main facilitator we identified was the widespread enthusiasm for the concept of group consultations among involved stakeholders. We identified this facilitator at the clinical, professional, organisational, and system levels under ‘ innovation relative advantage ’ in the ‘innovation’ domain and ‘mission alignment’ in the ‘inner setting’ . Professionals were especially positive about the peer support resulting from the group setting (Table 1Q12) and that the physical check-up handed participants tangible tools for change. Having various professionals present and arranging a warm handoff for follow-up care was also seen as an important benefit of the group consultations (Table 1Q13). Additionally, a sense of urgency for change facilitated implementation at the professional level under ‘tension for change’ in the ‘inner setting’ . Professionals expressed being fed up with the current system because citizens frequently returned to her practice with recurring physical complaints and questions (Table 1Q14). This motivated them to experiment with alternative ways of working, such as group consultations. Finally, at the clinical, professional, and organisational levels the adaptability of the initiative to the local context was identified as a facilitator under the ‘innovation adaptability’ of the ‘innovation’ domain. The respondents underlined the importance of adapting these types of initiatives to the local context where they are implemented (Table 1Q15), for example, considering cultural sensitivity. They emphasised that these groups consultations allow adaptation to various local contexts due to the flexible character of the different components, for example, by focusing on specific themes that are relevant in neighbourhood (Table 1Q16). Strategies We identified eight strategies that could be employed to improve the implementation of the group consultations (Table 2 ). We selected the strategy ‘ involve patients/consumers and family members ’ to improve the involvement of citizens in the design of the group. Methods to employ this strategy could include training health champions, experts by experience who are motivated to help others, to aid in the recruitment of participants, preparation of group consultations, be present during group consultation, and guide participants after the initial group consultation. They can represent the local community and ensure that the intervention is adjusted to the needs of the participants. Table 2 Main identified barriers and the matched strategy Barrier Implementation strategy from ERIC Limited involvement of citizens in the design of the group consultations. Involve patients/consumers and family members Gap between the group consultations and local follow-up initiatives Organise clinician implementation team meetings Involve patients/consumers and family members The lack of embedding of the group consultation into formal agreements/structures, resulting in dependence on the intrinsic motivation of involved partners for continuation of the initiative. Develop a formal implementation blueprint Obtain formal commitments Fragmentation of funding Use other payment schemes Develop resource sharing agreements Inadequate evaluation of effectiveness and the implementation process. Capture and share local knowledge Develop and organise quality monitoring systems We identified the strategies ‘ involve patients/consumers and family members ’ and ‘organise clinician implementation team meetings’ to bridge the gap between the group consultations and local follow-up initiatives. The aforementioned health champions could guide participants during and after the initial group consultation to find appropriate support or care. Additionally, clinician, or in the case of a cross-domain initiative, interdisciplinary, implementation team meetings could be employed to develop a feedback system between professionals after the initial group consultation to increase involvement. Interdisciplinary team meetings with involved professionals could be organised to monitor progress and discuss how to handle loss to follow-up among participants. To support this process, the use of ICT tools could be explored to aid communication between professionals. To embed the group consultations into formal agreements/structures, two strategies were selected: ‘develop a formal implementation blueprint’ and ‘obtain formal commitments’ . By creating a roadmap for implementation, the fixed and flexible parts of the group consultation can be determined. Roles and procedures could then be formalised and embedded via formal agreements. To ensure sustainability, ‘ use other payment schemes ’ and ‘ develop resource sharing agreements ’ were selected to overcome fragmentation of funding. Local agreements with the municipality and health insurance companies or national agreements are required for the payment structure. Finally, we selected ‘ capture and share local knowledge’ and ‘ develop and organise quality monitoring systems ‘ to promote systematic evaluation of the effectiveness of the group consultations and their implementation process. Iterative quantitative and qualitative evaluations would promote implementation, including the formulation of results and outcomes, a structured data gathering process, and a formal process evaluation. DISCUSSION We evaluated the implementation barriers and facilitators of an integrated care initiative that adopts interprofessional collaborative practice of patient-centred care for individuals with prediabetes in the form of group consultations, specifically targeting socioeconomically vulnerable groups in the Hague, the Netherlands. The use of CFIR in combination with RMIC enabled the generation of knowledge about what works in different contexts, extending beyond the specific research setting. On the basis of these findings, we propose strategies to mitigate key barriers to improve implementation and upscaling. Key barriers included insufficient citizen involvement in designing the intervention, which threatened normative integration because the content of the intervention was not adequately adjusted to meet the needs of the participants. As mentioned, normative integration is defined as the development and maintenance of a shared mission, vision, values and culture over the clinical, professional, organisational and system levels of the RMIC ( 27 ). When our findings are compared with those of previous studies, having citizen involvement in the design of the intervention seems to specifically influence the implementation of integrated care initiatives targeting socioeconomically vulnerable groups ( 18 ). Discrepancies in the conceptualisation of health between healthcare professionals and socioeconomically vulnerable citizens highlight the importance of citizen involvement when targeting this group ( 34 ). A previous study indicated that health is perceived and defined differently depending on socioeconomic position ( 34 ). In this study, highly educated people focused on the importance of well-being when defining health, whereas lower educated people mainly perceived health as the absence of disease ( 34 ). When these different views on health are not considered when designing a health promotion programme, effectiveness might be reduced because the priorities and goals of professionals and participants do not align ( 34 ). To address this, we recommend involving patients/consumers and family members in the design process and adapting the intervention to the local context. Since every local context is unique, this strategy would remain important when scaling the intervention to new neighbourhoods or cities. This process is facilitated by the adaptability of the intervention, as the intervention is suitable for tweaking on the basis of local needs while keeping core elements the same. The strategy of involving patients/consumers and family members was also proposed to bridge the gap between the group consultations and local follow-up initiatives, ensuring that participants receive appropriate and context sensitive information to choose suitable follow-ups. Additionally, organising interdisciplinary team meetings was suggested to establish a feedback system, thereby improving functional integration; so the supporting of and linking integration between the four levels of the RMIC ( 27 ). In this way, follow-up and lost-to-follow-up can be monitored and discussed on a regular basis. The key facilitators of implementation were the sense of urgency for change and the widespread enthusiasm for the concept, which played a critical role in fostering normative integration. The perceived urgency for change and mission-driven motivation among initiators have previously been reported to drive bottom-up initiatives ( 35 ). However, these other initiatives did encounter resistance from professionals who were supposed to collaborate in the new initiative, as they perceived the novel way of working as a violation of their professional autonomy ( 35 ). We potentially did not pick up on this phenomenon in our study because we included only early adopters, so professionals who were enthusiastic about the intervention and therefore decided themselves to participate ( 36 ). It would be valuable to reevaluate these determinants of implementation during the process of adoption into standard care. The enthusiasm of professionals driving implementation might also have had an unintended side effect: the strong motivation of professionals to go the extra mile could have reduced the perceived necessity of embedding the intervention into formal health and social care structures. The fragmentation of funding further complicated functional integration, in line with previous findings in both the Dutch context ( 13 , 18 , 35 , 37 , 38 ) and internationally ( 12 , 14 – 16 ). So although normative integration seemed to be going well, functional integration emerged as a challenge. This is a common phenomenon in bottom-up initiatives, where factors such as funding do not necessarily impede the initiation of change but become a barrier when initiatives move toward incorporation into standard practice ( 35 ). For integrated care initiatives, there is an additional layer of complexity since, in the Netherlands, medical care and social support are governed by separate laws and funded through distinct budgets, thereby making the financing of these initiatives particularly challenging. This fragmentation often leads to the discontinuation of promising or even proven effective initiatives after their pilot phase due to the absence of sustainable funding ( 13 , 37 ). The selected strategies to enhance functional integration include developing a formal implementation blueprint, obtaining formal commitments, exploring other payment schemes, and creating resource-sharing agreements. However, these last two strategies are complicated as real-world examples of sustainable payment models for integrated care initiatives that combine social and medical support remain scarce in the Dutch context. Nies et al. (2021) even described the separate reimbursement schemes for medical and social support as an “unsurmountable barrier” ( 13 ). Payers of both medical and social care—health care insurers and municipalities, respectively—are reluctant to invest in preventative activities because potential cost savings could fall under another budget ( 37 ). Therefore, in line with our findings, they tend to point fingers to each other. This underlines the importance of creating resource-sharing agreements, including how to deal with potential savings, and indicates the need to explore payment options within or beyond the current siloed health and social system to address such issues. For scaling and sustainable implementation, an embedded systematic evaluation of the intervention's effectiveness and implementation process are important ( 39 ). To address this, we propos capturing and sharing local knowledge and developing a quality monitoring system to drive ongoing improvements. The development of a learning health system would be an elegant example where these two strategies are combined ( 40 ). In a learning health system, research and health care delivery, or integrated care delivery, are fused by embedding advanced research methods within the care trajectory ( 40 ). Existing data infrastructures and insights from participants and professionals are used together to create rapid improvement cycles ( 40 ). To improve equity, citizens should be involved in this process and whether all relevant perspectives are represented or whose voices are absent should be monitored ( 40 ). Strengths and limitations A key strength of this study is the use of the RMIC framework in participant selection. By incorporating clinical, professional, organisational, and system-level perspectives, we ensured a diverse sample of respondents, representing various dimensions of implementation. Additionally, the use of the CFIR for data collection facilitated a broad focus during interviews and throughout the data collection process. During data analysis, this standardised determinants framework enabled the generation of knowledge about what works in different contexts, extending beyond the specific research setting. However, this approach carried the risk of a potential tunnel vision, focusing on the constructs within the framework and possibly overlooking themes outside its scope. Another limitation is the inclusion of early adopters in the study. Since the intervention has not yet been adopted into standard care, only early adopters working with the interventions exist. As a result, clinical, professional, and organisational integration may have been portrayed too optimistically, limiting the generalisability of findings beyond the scope of our research. Conclusions Citizen involvement in the design of the integrated care initiative was found to be a key determinant of implementation when targeting socioeconomically vulnerable groups. Although a shared sense of urgency for change and widespread enthusiasm among stakeholders were drivers of implementation and facilitated normative integration, they might have reduced the perceived necessity for functional integration. The lack of embedding of the initiative into formal structures and fragmented funding threatens its scalable and sustainable impact. Various strategies as defined by the ERIC taxonomy could be employed to promote implementation and upscaling. When targeting socioeconomically vulnerable groups, involving the target population in designing the intervention and adapting the intervention to the local context were found to be especially important. The absence of a sustainable funding structure was a main barrier when incorporating the integrated care initiative into standard care, regardless of the suitability of these initiatives to improve the health of socioeconomically vulnerable groups. The use of other payment schemes to surmount the separate reimbursement schemes for medical and social support could pose a suitable strategy to overcome this barrier. Embedded evaluation, possibly using a learning health system, is recommended for sustainable implementation and upscaling. Abbreviations CFIR Consolidated Framework of Implementation Research RMIC Rainbow Model of Integrated Care ERIC Expert Recommendation for Implementing Change nWMO Research not falling under the Dutch Medical Research with Human Subjects Law Q Quote Declarations Ethics approval and consent to participate The Medical Ethical Review Board of Leiden University Medical Center mandated the review of research not falling under the Dutch Medical Research with Human Subjects Law (nWMO) to individual nWMO committees at Leiden University Medical Center. The nWMO committee reviewed the proposal and provided a declaration of no objection (non-WMO approval number: 24-3066). This study has been further approved by the scientific committee of the department of Public Health and Primary Care at Leiden University Medical Center (Reference number: WSC-2024-37). All the interviewees provided written informed consent. The participants in the focus group gave verbal consent after being informed about what data we would gather and how. No personal data were gathered during the focus group. Consent for publication All the interviewees provided written informed consent using an informed consent form approved by our institution. Availability of data and materials The datasets generated and analysed during the current study are not publicly available for privacy reasons. Competing interests The authors declare that they have no competing interests Funding Made possible in part by The Netherlands Organisation for Health Research and Development (ZonMw), file number 10390102210010. Authors' contributions JGtB and RCV conceived the study and developed the study design, with input from JKdJ. JGtB, TK, and MV gathered the data. JGtB, AFTME, and RCV designed the analyses. JGtB, AFTME, and RCV contributed to the data analyses and interpretation. JGtB drafted the manuscript, and all the authors contributed to editing the manuscript and approved the final submitted version. Acknowledgements We acknowledge Rianne Kleijn, Loïse M. Jacz-Kruithof, and Naomi Minderhout for evaluating our findings to assess accuracy and improve credibility. Furthermore, many thanks to all the respondents; we highly appreciate their insights, honesty, and time. Authors’ information Jonne G. ter Braake, Annefrans F.T.M. van Ede, Jessica Kiefte-de Jong, and Rimke C. Vos work in research for an academic hospital. Jonne G. ter Braake is doing her PhD on social determinants of cardiovascular care; Annefrans F.T.M. van Ede works as a postdoc on the implementation of Population Health Management; Jessica Kiefte-de Jong is a professor of Population Health; and Rimke C. Vos works as an associate professor of implementation of Population Health Management. Jonne G. ter Braake was present during the group consultation’s implementation team meetings in 2024 and Rimke C. Vos has been part of the implementation team since 2019. Tara Kwakkernaat and Maud Verhoeven were both students at the time of this study and were involved in data collection as part of her bachelor’s dissertation in Health Policy and Management and her master’s dissertation in Population Heath Management, respectively. References Beran M, Schram MT. Prediabetes in Nederland. Diabetes Fonds: Maastricht University; Maastricht UMC. Echouffo-Tcheugui JB, Selvin E. Pre-Diabetes and What It Means: The Epidemiological Evidence. Annual Review Public Health. 2021;42:59-77. Ligthart S, van Herpt TTW, Leening MJG, Kavousi M, Hofman A, Stricker BHC, et al. Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes: a prospective cohort study. The Lancet Diabetes & Endocrinology. 2016;4(1):44-51. 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Implementation of an integrated community approach in deprived neighbourhoods: a theory-based process evaluation using the Consolidated Framework for Implementation Research (CFIR). Scandinavian Journal of Public Health. 2023:14034948231199804. Zavrnik Č, Danhieux K, Monarres MH, Stojnić N, Lukančič MM, Martens M, et al. Scaling-up an integrated care for patients with non-communicable diseases: An analysis of healthcare barriers and facilitators in Slovenia and Belgium. Slovenian Journal of Public Health. 2021;60(3):158-66. Integraal Zorgakkoord. 2022. Ministerie van Volksgezondheid WeS. GALA Gezond en Actief Leven Akkoord. 2023. Skoglund G, Nilsson BB, Olsen CF, Bergland A, Hilde G. Facilitators and barriers for lifestyle change in people with prediabetes: a meta-synthesis of qualitative studies. BMC Public Health. 2022;22(1):553. Proctor E, Silmere H, Raghavan R, Hovmand P, Aarons G, Bunger A, et al. Outcomes for Implementation Research: Conceptual Distinctions, Measurement Challenges, and Research Agenda. Administration and Policy in Mental Health and Mental Health Services Research. 2011;38(2):65-76. Berwick DM, Nolan TW, Whittington J. The Triple Aim: Care, Health, And Cost. Health Affairs. 2008;27(3):759-69. Huber M, van Vliet M, Giezenberg M, Winkens B, Heerkens Y, Dagnelie PC, et al. Towards a ‘patient-centred’ operationalisation of the new dynamic concept of health: a mixed methods study. BMJ Open. 2016;6(1):e010091. Damschroder LJ, Reardon CM, Widerquist MAO, Lowery J. The updated Consolidated Framework for Implementation Research based on user feedback. Implementation Science. 2022;17(1):75. Valentijn PP, Schepman SM, Opheij W, Bruijnzeels MA. Understanding integrated care: a comprehensive conceptual framework based on the integrative functions of primary care. International Journal of Integrated Care. 2013. Powell BJ, Waltz TJ, Chinman MJ, Damschroder LJ, Smith JL, Matthieu MM, et al. A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project. Implementation Science. 2015;10(1):21. Hennink MM, Kaiser BN, Marconi VC. Code Saturation Versus Meaning Saturation: How Many Interviews Are Enough? Qualitative Health Research. 2016;27(4):591-608. Rutakumwa R, Mugisha JO, Bernays S, Kabunga E, Tumwekwase G, Mbonye M, et al. Conducting in-depth interviews with and without voice recorders: a comparative analysis. Qualitative Research. 2019;20(5):565-81. Ritchie J, Spencer L. Qualitative data analysis for applied policy research. In: Bryman A, Burgess RG, editors. Analysing qualitative data: Routledge, London; 1994. p. 173-94. Smith B, McGannon KR. Developing rigor in qualitative research: problems and opportunities within sport and exercise psychology. International Review of Sport and Exercise Psychology. 2018;11(1):101-21. Strategy Design Consolidated Framework for Implementation Research [Available from: https://cfirguide.org/choosing-strategies/. Stronks K, Hoeymans N, Haverkamp B, den Hertog FRJ, van Bon-Martens MJH, Galenkamp H, et al. Do conceptualisations of health differ across social strata? A concept mapping study among lay people. BMJ Open. 2018;8(4):e020210. Krijgsheld M, Schmidt E, Levels E, Schuurmans M. Healthcare professionals as change agents: Factors influencing bottom-up, personal initiatives on appropriate care, a qualitative study in the Netherlands. Health Policy. 2024;147:105120. Berwick DM. Disseminating Innovations in Health Care. JAMA. 2003;289(15):1969-75. Holterman S, Lahr M, Wynia K, Hettinga M, Buskens E. Integrated Care for Older Adults: A Struggle for Sustained Implementation in Northern Netherlands. International Journal of Integrated Care. 2020. Hilhorst P, Wijngaart Mvd. Samenwerking sociaal en medisch domein. Een verkenning. EMMA: EMMA; 2024. European Commission: Directorate-General for H, Food S. Blocks – Tools and methodologies to assess integrated care in Europe – Report by the Expert Group on Health Systems Performance Assessment: Publications Office; 2017. Reid RJ, Wodchis WP, Kuluski K, Lee-Foon NK, Lavis JN, Rosella LC, et al. Actioning the Learning Health System: An applied framework for integrating research into health systems. SSM - Health Systems. 2024;2:100010. Additional Declarations No competing interests reported. Supplementary Files Additionalfile1.docx Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-5849625","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":422799148,"identity":"836b3bab-fce8-4542-97b5-745e2b153296","order_by":0,"name":"Jonne G. ter Braake","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA5klEQVRIiWNgGAWjYBACxgYowwDCsZGBcAsIaDmA0JLGgzABH0DScpiwFuYG9gvMHyruMZhLH374cUbFeR6Da4cfMBfg0cLYwFPAcOBMMYNlX5qx5IYzt3kMbqcZMM/AryWB4WBbAoPBGQYDyYdtIC05DMw8BLX8A2lh//zz4b9zxGhhP8BwsAGkhcdMcmPDASK0NPMAvXIsgcGyh6fMcsaxZB5JoF8O49Ni2N7+8EFFTQKDOQ/75ps9NXZyfLeTHz7mqcCjpZnH4ACQrm9AFj2AWwMDgzwD+wN88qNgFIyCUTAKGBgA3clO7VLso3UAAAAASUVORK5CYII=","orcid":"","institution":"Health Campus The Hague, Leiden University Medical Center","correspondingAuthor":true,"prefix":"","firstName":"Jonne","middleName":"G. ter","lastName":"Braake","suffix":""},{"id":422799149,"identity":"04e180ba-9e05-42f6-a2e2-daef09a0a617","order_by":1,"name":"Annefrans F.T.M. Ede","email":"","orcid":"","institution":"Health Campus The Hague, Leiden University Medical Center","correspondingAuthor":false,"prefix":"","firstName":"Annefrans","middleName":"F.T.M.","lastName":"Ede","suffix":""},{"id":422799150,"identity":"e9b0c735-f305-40c9-a734-b5abaee82121","order_by":2,"name":"Tara Kwakkernaat","email":"","orcid":"","institution":"Health Campus The Hague, Leiden University Medical Center","correspondingAuthor":false,"prefix":"","firstName":"Tara","middleName":"","lastName":"Kwakkernaat","suffix":""},{"id":422799151,"identity":"161c0545-9d57-478e-9967-c2ee27daad9a","order_by":3,"name":"Maud J. Verhoeven","email":"","orcid":"","institution":"Health Campus The Hague, Leiden University Medical Center","correspondingAuthor":false,"prefix":"","firstName":"Maud","middleName":"J.","lastName":"Verhoeven","suffix":""},{"id":422799155,"identity":"196dd45c-3854-4711-8f29-856f3eb3df40","order_by":4,"name":"Jessica C. Kiefte-de Jong","email":"","orcid":"","institution":"Health Campus The Hague, Leiden University Medical Center","correspondingAuthor":false,"prefix":"","firstName":"Jessica","middleName":"C. Kiefte-de","lastName":"Jong","suffix":""},{"id":422799157,"identity":"cb52b351-2267-4e09-95b3-9ecc713f77dd","order_by":5,"name":"Rimke C. 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Prediabetes is characterised by elevated blood glucose levels that are not yet high enough to be classified as diabetes (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e). Around 70% of people with prediabetes develop type 2 diabetes within ten years (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e). The deterioration from prediabetes to diabetes was found to be socially patterned, with socioeconomically vulnerable people having an increased risk of developing diabetes compared with their more affluent peers (\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e). As within the diabetes population, the prevalence of prediabetes is nearly double in the most deprived one-third of the population compared with the least deprived one-third of the population, with a prevalence of 27% and 15%, respectively (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e). To prevent the deterioration from prediabetes to diabetes, lifestyle interventions have proven effective in restoring normal blood glucose levels and improving cardiometabolic markers (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e, \u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e). However, social-contextual constraints can hinder lifestyle changes if not properly addressed, for example individual characteristics including socioeconomic position and neighbourhood characteristics (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e, \u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e). This can place socioeconomically vulnerable people at a further disadvantage. Although initiatives are available to mitigate these social constraints, many citizens do not receive appropriate support matched to their needs because of fragmentation of the health and social care systems (unpublished findings).\u003c/p\u003e \u003cp\u003eAcross different contexts, there is growing recognition of the need to integrate social support and medical care. Health advocates emphasise its potential to deliver personalised care, enhance health outcomes, and foster greater equity within the healthcare system (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e, \u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e). Using an integrated care approach, underlying issues hindering lifestyle change, such as debt or unemployment, could be addressed first before the focus is shifted to stimulating lifestyle change (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e). This approach has the potential to improve health especially in socioeconomically vulnerable people (\u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eDespite the promise of integrated care initiatives, the incorporation of these initiatives into standard care is rare (\u003cspan additionalcitationids=\"CR12\" citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e). Previously identified barriers include difficulties in sharing information between professionals and/or organisations (\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e, \u003cspan additionalcitationids=\"CR15 CR16\" citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e), funding (\u003cspan additionalcitationids=\"CR13 CR14 CR15 CR16 CR17\" citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e), and the accessibility of locations (\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e, \u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e). Facilitators include effective communication and collaboration between professionals (\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e, \u003cspan additionalcitationids=\"CR15 CR16\" citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e). Facilitators identified when specifically targeting socioeconomically vulnerable groups include citizen engagement and needs assessment and the use of a positive health approach. From a positive health perspective, health encompasses more than just addressing disease and illness; it also involves an individual's perceived control and capacity to manage life's challenges (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e). As for integrated care initiatives in general, funding has proven to be a barrier when this specific population is targeted (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eInformation on whether the identified barriers and facilitators are similar when targeting socioeconomically vulnerable groups remains scarce, despite the potential benefits of integrated care for these groups (\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e, \u003cspan additionalcitationids=\"CR21\" citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e). Therefore, we used group consultations that bridge the medical and social domain, targeting citizens with prediabetes living in socioeconomically vulnerable neighbourhoods in The Hague, the Netherlands, as a case example of an integrated care initiative. These group consultations are characterised by interprofessional collaborative practice of patient-centred care for individuals with prediabetes and were initially provided in two neighbourhoods in The Hague, The Netherlands. An implementation team of various professionals is now exploring upscaling to additional neighbourhoods. For this purpose, insights into implementation barriers and facilitators, as well as the selection of context-sensitive strategies for implementation and upscaling, are needed. Therefore, we aim to evaluate the implementation barriers and facilitators of this integrated care initiative which targets socioeconomically vulnerable groups and select strategies to improve implementation and upscaling.\u003c/p\u003e"},{"header":"METHODS","content":"\u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003eStudy design and setting\u003c/h2\u003e \u003cp\u003eWe conducted a case study using a qualitative design combining individual interviews and a focus group to evaluate barriers and facilitators of the implementation of an integrated care initiative that adopts interprofessional collaborative practice of patient-centred care for individuals with prediabetes in the form of group consultations (\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe group consultations were developed by a primary care physician motivated by her observations that some socioeconomically vulnerable people with prediabetes frequently returned to her practice with recurring physical complaints. These complaints often stem from unresolved underlying social constraints that remain unaddressed in traditional primary health care. She decided to adopt a Population Health Management approach (\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e) and use interprofessional collaborative practice to better adjust care to the multifaceted needs of this vulnerable group. She collaborated with a neighbourhood sports coach, a social worker, and medical staff to design a group consultation, aiming to familiarise citizens with available local support tailored to their needs. During a single 90-minute session, various professionals from different disciplines, including but not limited to a primary care physician, neighbourhood sports coach, and social worker, together provide a group consultation where the interrelatedness of social and medical problems is discussed from a positive health perspective (\u003cspan citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e) a physical check-up is conducted, and a warm handoff is arranged for initiatives in the neighbourhood on the basis of the social and medical needs of the participants. Follow-up trajectories could include sessions with the neighbourhood sports coach, a lifestyle coach, or social worker. A group follow-up session is provided six months after the initial session. The groups generally consisted of between four and 15 participants. These group consultations were initiated in two neighbourhoods in 2019, and in 2023 scaling commenced to additional neighbourhoods in The Hague. An implementation team, including health care professionals, community representatives, and researchers, was involved in the upscaling of the intervention.\u003c/p\u003e \u003c/div\u003e\n\u003ch3\u003eTheoretical frameworks and data collection\u003c/h3\u003e\n\u003cp\u003e We used the implementation determinant framework Consolidated Framework of Implementation Research (CFIR) in combination with the Rainbow Model of Integrated Care (RMIC) to guide data collection and analysis.\u003c/p\u003e \u003cp\u003eThe CFIR offers a standardised structure for identifying barriers and facilitators of implementation, enabling knowledge generation on what works where, beyond the specific research settings (\u003cspan citationid=\"CR26\" class=\"CitationRef\"\u003e26\u003c/span\u003e). This framework identifies six domains: innovation, the outer setting, the inner setting, individuals, and the implementation process; each domain is composed of a number of constructs (\u003cspan citationid=\"CR26\" class=\"CitationRef\"\u003e26\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe RMIC was developed to better understand the concept of integrated care (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). The model conceptualises the process of integrating care through six dimensions: clinical, professional, organisational, system, functional, and normative integration (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). To deliver integrated care, integration across all levels is needed. The first four dimensions explore integration from the micro to the macro level. \u003cem\u003eClinical integration\u003c/em\u003e is defined as the coordination of patient care activities and whether services improve an individual\u0026rsquo;s overall well-being; \u003cem\u003eprofessional integration\u003c/em\u003e explores the collaboration among healthcare professionals across disciplines; \u003cem\u003eorganisational integration\u003c/em\u003e analyses the alignment and cooperation among healthcare organisations; and \u003cem\u003esystem integration\u003c/em\u003e considers the broader health system's policies, regulations, and structures that influence care delivery (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). Functional integration supports and links integration over these four levels, and normative integration is defined as the development and maintenance of a shared mission, vision, values and culture over the four levels (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). We used the first four dimensions to guide participant selection and structure findings.\u003c/p\u003e \u003cp\u003eWe employed the CFIR\u0026rsquo;s Expert Recommendation for Implementing Change (ERIC) framework for the selection of implementation strategies matched to the identified barriers and facilitators (\u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e). This framework defines implementation strategies based on input from a wide range of stakeholders (\u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e). By using this framework, we ensured the unambiguous use of previously defined strategies.\u003c/p\u003e \u003cp\u003eData collection took place between April and October 2024 and is described in detail below.\u003c/p\u003e\n\u003ch3\u003eInterviews\u003c/h3\u003e\n\u003cp\u003eSemi-structured interviews guided by the CFIR framework were conducted with a varied group of stakeholders directly or indirectly involved in the organisation of the group consultations. The interviews were conducted in-person, via videocall or by telephone, depending on the preference of the interviewee. We used purposive sampling guided by the RMIC levels to select participants. Professional networks of implementation team members were used in this process. A priori the sample size to reach meaning saturation was estimated at approximately 26 interviews, as we expected partial overlap in barriers and facilitators over the four levels of the RMIC. Meaning saturation was reached when no new barriers or facilitators were identified nor refinement was needed (\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e). As CFIR includes a comprehensive list of constructs, a selection of topics was chosen prior to each interview based on the knowledge and expertise of the respondent. Additional constructs were discussed when deemed appropriate.\u003c/p\u003e \u003cp\u003eThe majority of interviews were conducted by JGtB, six together with a student (TK or MV) and three by a student alone (TK or MV). The interviews were recorded and transcribed verbatim.\u003c/p\u003e\n\u003ch3\u003eFocus group\u003c/h3\u003e\n\u003cp\u003eA semi-structured in-person focus group was organised with a women\u0026rsquo;s group of experts by experience volunteering in the neighbourhood. The group consisted of 16 women, 11 of whom had previously participated in a group consultation. The focus group provided further insights into barriers and facilitators at the clinical level of implementation and was used to validate and enrich findings from the individual interviews. The focus group was not recorded. Instead, field notes were made during the session and subsequently expanded by two authors (RCV and JGB) who were present during the discussion. This approach was found to be more appropriate because audio recording potentially changes the group dynamic as participants experience nervousness over their voices being recorded (\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e).\u003c/p\u003e \u003cdiv id=\"Sec7\" class=\"Section2\"\u003e \u003ch2\u003eData analysis\u003c/h2\u003e \u003cp\u003eWe used Framework analysis, a descriptive qualitative approach originating from policy research, to analyse the data obtained during interviews and the focus group (\u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e). Framework analysis is a method to describe and interpret what is happening in a particular setting via five iterative steps: familiarization, identification of a thematic framework, indexing, charting, and mapping and interpretation (\u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e). All steps were conducted by the first author (JGtB) in collaboration with a \u0026lsquo;critical friend\u0026rsquo; (\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e), AFTME, and overseen by RCV. The five steps were discussed and revised during critical dialogue over several sessions. The dialogue provided a theoretical sounding board where the thought process of the first author was evaluated, alternative interpretations were coined, and interpretations were revised accordingly.\u003c/p\u003e \u003cp\u003eA priori, the CFIR was identified as a suitable framework to guide data analysis. Based on the familiarisation phase, deductive use of CFIR domains and constructs for indexing was deemed appropriate. To enable further discussion of the indexing in a time-efficient manner, a step between indexing and charting was added. We first arranged the indexed data according to the CFIR constructs via a \u0026lsquo;cut and paste\u0026rsquo; approach, after which adjustments to the indexing were made to reach consensus. A distilled summary per construct was then charted, ordered by the RMIC levels. We used mapping and interpretation to define barriers and facilitators per construct and RMIC level using the distilled summaries. This process was conducted iteratively until meaning saturation was reached.\u003c/p\u003e \u003cp\u003eThen, related barriers and facilitators were combined by JGB and RCV and a selection was made to identify those most prominently needing strategies to overcome the barrier or leverage the facilitator. This process was evaluated by two members of the implementation team and an independent expert familiar with the intervention who were not involved in this study.\u003c/p\u003e \u003cp\u003eWe matched the implementation strategies to the selected barriers using CFIR\u0026rsquo;s ERIC matching tool (\u003cspan citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e).\u003c/p\u003e \u003c/div\u003e"},{"header":"RESULTS","content":"\u003cp\u003eWe conducted 28 interviews and one focus group (n\u0026thinsp;=\u0026thinsp;16). Four interviews and the focus group were with professionals operating at the clinical level of the RMIC, eight interviews at the professional level, nine at the organisational level, and seven at the system level. The interviewees included but were not limited to experts by experience, community leaders, medical and social care professionals, members of the expert team organising the group consultations and representatives of the municipality, health insurance and the government.\u003c/p\u003e \u003cp\u003eWe identified 50 unique barriers and 30 unique facilitators of the implementation of the group consultations (Additional file 1). Ten more determinants were identified; these determinants were present in some neighbourhoods and absent in others and functioned as facilitators when present and barriers when absent. From these 90 determinants, we selected five main barriers and three main facilitators (Table\u0026nbsp;\u003cspan refid=\"Tab1\" class=\"InternalRef\"\u003e1\u003c/span\u003e). Implementation strategies were identified for the main barriers. These barriers, facilitators, and strategies are further discussed below.\u003c/p\u003e \u003cp\u003e \u003cdiv class=\"gridtable\"\u003e\u003ctable float=\"Yes\" id=\"Tab1\" border=\"1\"\u003e \u003ccaption language=\"En\"\u003e \u003cdiv class=\"CaptionNumber\"\u003eTable 1\u003c/div\u003e \u003cdiv class=\"CaptionContent\"\u003e \u003cp\u003eSelected barriers and facilitators, their CFIR determinant and level of RMIC, with an illustrative quote.\u003c/p\u003e \u003c/div\u003e \u003c/caption\u003e \u003ccolgroup cols=\"5\"\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c1\" colnum=\"1\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c2\" colnum=\"2\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c3\" colnum=\"3\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c4\" colnum=\"4\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c5\" colnum=\"5\"\u003e\u003c/div\u003e \u003cthead\u003e \u003ctr\u003e \u003cth align=\"left\" colname=\"c1\"\u003e\u0026nbsp;\u003c/th\u003e \u003cth align=\"left\" colname=\"c2\"\u003e \u003cp\u003eDeterminant\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c3\"\u003e \u003cp\u003eDeterminant CFIR\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c4\"\u003e \u003cp\u003eLevel of the RMIC\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQuotes\u003c/p\u003e \u003c/th\u003e \u003c/tr\u003e \u003c/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\" morerows=\"4\" rowspan=\"5\"\u003e \u003cp\u003e\u003cb\u003eBarriers\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eInsufficient involvement of citizens in the design of the group consultations.\u003c/p\u003e \u003cp\u003eImportant sub barriers:\u003c/p\u003e \u003cp\u003e- The examples used during the group consultations are not tailored to the cultural background of participants.\u003c/p\u003e \u003cp\u003e- Detachment between residents and professionals reduces trust\u003c/p\u003e \u003cp\u003e- Many citizens think it is important to have separate groups for men and for women\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eProcess - Assessing needs\u003c/p\u003e \u003cp\u003eInnovation \u0026ndash; Innovation design\u003c/p\u003e \u003cp\u003eOuter setting \u0026ndash; Local conditions\u003c/p\u003e \u003cp\u003eOuter setting \u0026ndash; Local attitudes\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eClinical, professional, and organisational\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ1: \u0026ldquo;But it also has to do with: you put things in front of me that I don't like. You want me to cook certain things that I don't know how to cook.\u0026rdquo; \u0026ndash; Clinical level\u003c/p\u003e \u003cp\u003eQ2: \u0026ldquo;This is a theme about losing weight. Especially among women, it is a private theme. It's a... It also has to do with self-confidence, self-confidence. So in a group where there are men there, you're not really going to be able to get that out, so out of, that a woman is going to tell something so intimate.\u0026rdquo; \u0026ndash; Clinical level\u003c/p\u003e \u003cp\u003eQ3: \u0026ldquo;I also hope that the consultations will be carried even more by the local residents themselves, so that it really comes from the community. And that they also get a voice in designing the consultations, for example.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003cp\u003eQ4: \u0026ldquo;Adjusting [the intervention] to the group, there\u0026rsquo;s still a lot to be done in that, in my opinion\u0026rdquo; \u0026ndash; Organisational level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eGap between the group consultations and local follow-up initiatives\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eInnovation \u0026ndash; Innovation design\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eClinical, professional, and organisational\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ5: \u0026ldquo;At this one there were lots of dieticians and someone from, for people with financial problems, for people with financial, you name it. All sorts of things were there. Eating problems.[...] Heart foundation was also there and I understood that all. Also understand why they were invited. I was only wondering like: what's the added value? The performance did go nicely. It was nice. The atmosphere and everything. That was all right. But after that I did notice some people were like: what am I here for? What is the actual help?\u0026rdquo; \u0026ndash; Clinical level\u003c/p\u003e \u003cp\u003eQ6: \u0026ldquo;Often they are in different trajectories and then it may occur that I lose track of them, but they are still actually working on a trajectory, which also originated from the group consultation. So that link, if indeed something is documented or streamlined, that we can also better keep track on that. [...] So often you lose the people who try something and it doesn't work out and then think: it didn't work out, I'll stop. Whereas a moment of contact or a signal of: this person has stopped, if we can pick this up again, it will be easier to pick up the trajectory again.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eThe lack of embedding of the group consultation into formal agreements/structures.\u003c/p\u003e \u003cp\u003eImportant sub barrier: Roles within the implementation team are unclear.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eProcess \u0026ndash; Planning\u003c/p\u003e \u003cp\u003eIndividuals \u0026ndash; Implementation leads\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eOrganisational and system\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ7: \u0026ldquo;For that to spread out completely in the neighbourhoods, there is - I think - still a lot depending on enthusiastic colleagues - professionals - rolling that out. Ideally, you would like to secure that in a function within.... In a neighbourhood, for instance. That it is not person-dependent, but more embedded.\u0026rdquo; \u0026ndash; Organisational level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eFragmentation of funding\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eOuter setting \u0026ndash; Local conditions;\u003c/p\u003e \u003cp\u003eInner setting \u0026ndash; Available resources\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eProfessional, organisational, and system\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ8: \u0026ldquo;[\u0026hellip;]funding is a problem and has been for some time, because on the one hand you have the angle from medical support and support from the social domain, with health insurer and municipality looking at each other like: who is going to pay for what?\u0026rdquo; \u0026ndash; Organisational level\u003c/p\u003e \u003cp\u003eQ9: \u0026ldquo;And yes, you know, I think this is actually another one of those typical annoying cases of the responsibility lies everywhere and therefore nowhere.\u0026rdquo; \u0026ndash; System level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eInadequate evaluation of effectiveness and the implementation process.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eProcess \u0026ndash; Reflecting and evaluating\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eProfessional, organisational, and system\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ10: \u0026ldquo;Sure she asked that at some point. Sure that that also came up and I may have mentioned something. But not very well-founded and not very well thought out, I think.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003cp\u003eQ11: \u0026ldquo;But to put it very simply: to get a payment title for group consultations, you will have to present results from the field, if you would want to pay for it from the ZVW [Health Insurance Act].\u0026rdquo; \u0026ndash; System level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\" morerows=\"2\" rowspan=\"3\"\u003e \u003cp\u003e\u003cb\u003eFacilitators\u003c/b\u003e\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eWidespread enthusiasm for the concept of the group consultations\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eInnovation \u0026ndash; Innovation relative advantage\u003c/p\u003e \u003cp\u003eInner setting \u0026ndash; Mission alignment\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eClinical, professional, organisational, and system level\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ12: \u0026ldquo;During group consultations, we notice that people truly feel heard.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003cp\u003eQ13: \u0026ldquo;Well, if you go to one of those group consultations [\u0026hellip;] and you find out there: who is that dietician? Oh, [\u0026hellip;] that seems like a really nice person. And you can make an appointment right away, that\u0026rsquo;s of course perfect. Then you really have, just that warm referral.\u0026rdquo; \u0026ndash; Organisational level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eSense of urgency for change among stakeholders\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eInner setting \u0026ndash; Tension for change\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eProfessional level\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ14: \u0026ldquo;I said: well, I'm open to that kind of thing too, just offering care in a different way instead of just one-to-one. Because sometimes you think: \u0026lsquo;Hello, does it sink in?\u0026rsquo; \u0026lsquo;Or what about the advice I give?\u0026rsquo; And then when someone says, for example, after ten times, \u0026ldquo;I've never heard that before.\u0026rdquo; Then I think, I think I've already told them ten times.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eAdaptability of the initiative to the local context\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c3\"\u003e \u003cp\u003eInnovation \u0026ndash; Innovation adaptability\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c4\"\u003e \u003cp\u003eClinical, professional, and organisational level\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c5\"\u003e \u003cp\u003eQ15: \u0026ldquo;Yes, because you see that that's important for success. That you respond to the needs in the neighbourhood\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003cp\u003eQ16: \u0026ldquo;If there are a lot of questions regarding quitting smoking, then we'll grab that quit smoking coach again. So that way you can adjust it a little bit each time too.\u0026rdquo; \u0026ndash; Professional level\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003c/tbody\u003e \u003c/colgroup\u003e \u003c/table\u003e\u003c/div\u003e \u003c/p\u003e \u003cp\u003eTable\u0026nbsp;\u003cspan refid=\"Tab1\" class=\"InternalRef\"\u003e1\u003c/span\u003e: Selected barriers and facilitators, their CFIR determinant and level of RMIC, with an illustrative quote.\u003c/p\u003e\n\u003ch3\u003eBarriers\u003c/h3\u003e\n\u003cp\u003eThe first main barrier was the insufficient involvement of citizens in the design of the group consultations, which was identified as being part of the \u003cem\u003e\u0026lsquo;assessing needs\u0026rsquo;\u003c/em\u003e determinant of the \u003cem\u003e\u0026lsquo;process\u0026rsquo;\u003c/em\u003e domain of CFIR. This barrier was identified at the clinical, professional, and organisational levels of the RMIC. The limited involvement of citizens in the design and implementation process resulted in several sub barriers, such as inadequate tailoring of the intervention to the cultural background of participants and reduced trust (Table\u0026nbsp;\u003cspan refid=\"Tab1\" class=\"InternalRef\"\u003e1\u003c/span\u003e Quote (Q) 1\u0026ndash;4).\u003c/p\u003e \u003cp\u003eA second barrier was found at the clinical, professional, and organisational levels under \u003cem\u003e\u0026lsquo;innovation design\u0026rsquo;\u003c/em\u003e, which is part of the \u003cem\u003e\u0026lsquo;innovation\u0026rsquo;\u003c/em\u003e domain. The respondents reported that there remained a gap between the group consultations and local follow-up initiatives, such as sessions with the neighbourhood sports coach, a lifestyle coach, or social worker. Two distinct gaps were reported. The participants felt that they did not receive adequate information about the follow-up steps, thereby preventing the initiation of a follow-up trajectory (Table\u0026nbsp;1Q5). The professionals mentioned that when they lost touch with participants, they were unaware of whether these participants were still seen by other colleagues and thus \u0026ldquo;in the system\u0026rdquo; or fell off the professionals\u0026rsquo; radar. Due to the lack of a structured feedback system, professionals felt demotivated to keep track of lost participants (Table\u0026nbsp;1Q6).\u003c/p\u003e \u003cp\u003eThe third barrier we identified was the lack of embedding of the group consultation into formal agreements/structures. This barrier was identified at the organisational and system levels as a determinant of \u003cem\u003e\u0026lsquo;planning\u0026rsquo;\u003c/em\u003e under the \u003cem\u003e\u0026lsquo;process\u0026rsquo;\u003c/em\u003e domain. Currently, the initiative relies on efforts from various enthusiastic professionals and partners that support continuation, as described later under facilitators. However, participants mentioned the importance of embedding the initiative into formal structures to safeguard sustainability and scaling regardless of enthusiastic professionals potentially switching positions or not being able to put in the same effort (Table\u0026nbsp;1Q7).\u003c/p\u003e \u003cp\u003eGuaranteeing the sustainability of the initiative related to the fourth barrier: the fragmentation of funding. This determinant was identified at the professional, organisational, and system levels and categorised under both the \u003cem\u003e\u0026lsquo;local conditions\u0026rsquo;\u003c/em\u003e in the \u003cem\u003e\u0026lsquo;outer setting\u0026rsquo;\u003c/em\u003e and \u003cem\u003e\u0026lsquo;available resources\u0026rsquo;\u003c/em\u003e in the \u003cem\u003e\u0026lsquo;inner setting\u0026rsquo;\u003c/em\u003e. The respondents elaborated on the complexity of the Dutch health system, as healthcare and social support are regulated and funded according to two different laws with different paying parties, and the lack of formal responsibility for health and prevention. Interviewees explained that funding parties point fingers to each other to take initiative (Table\u0026nbsp;1Q8 and Q9). No sustainable funding agreements have been made yet, thereby causing the initiative to rely on temporary funding, which threatens sustainability.\u003c/p\u003e \u003cp\u003eThe last main barrier was inadequate evaluation of effectiveness and the implementation process. This barrier was identified at the professional, organisational, and system levels under the \u003cem\u003e\u0026lsquo;reflecting and evaluating\u0026rsquo;\u003c/em\u003e construct of the \u003cem\u003e\u0026lsquo;process\u0026rsquo;\u003c/em\u003e domain. This barrier was multifaceted. The interviewed professionals had different perceptions of whether the process is currently being monitored. While some described some sort of process evaluation and monitoring system, others mentioned not being included in this process (Table\u0026nbsp;1Q10). Overall, there seemed to be no clear structure in the process or effectiveness evaluation. The respondents also emphasised the difficulties associated with evaluating the effectiveness of preventative initiatives. They explained that not all participants change their behaviour right away; some might forget about it for some time and then after an additional trigger use the information received. Long-term evaluation is needed to capture these delayed effects. The respondents at the system level emphasised the importance of evaluating the effectiveness to secure sustainable funding (Table\u0026nbsp;1Q11).\u003c/p\u003e\n\u003ch3\u003eFacilitators\u003c/h3\u003e\n\u003cp\u003eThe first main facilitator we identified was the widespread enthusiasm for the concept of group consultations among involved stakeholders. We identified this facilitator at the clinical, professional, organisational, and system levels under \u0026lsquo;\u003cem\u003einnovation relative advantage\u003c/em\u003e\u0026rsquo; in the \u003cem\u003e\u0026lsquo;innovation\u0026rsquo;\u003c/em\u003e domain and \u003cem\u003e\u0026lsquo;mission alignment\u0026rsquo;\u003c/em\u003e in the \u003cem\u003e\u0026lsquo;inner setting\u0026rsquo;\u003c/em\u003e. Professionals were especially positive about the peer support resulting from the group setting (Table\u0026nbsp;1Q12) and that the physical check-up handed participants tangible tools for change. Having various professionals present and arranging a warm handoff for follow-up care was also seen as an important benefit of the group consultations (Table\u0026nbsp;1Q13).\u003c/p\u003e \u003cp\u003eAdditionally, a sense of urgency for change facilitated implementation at the professional level under \u003cem\u003e\u0026lsquo;tension for change\u0026rsquo;\u003c/em\u003e in the \u003cem\u003e\u0026lsquo;inner setting\u0026rsquo;\u003c/em\u003e. Professionals expressed being fed up with the current system because citizens frequently returned to her practice with recurring physical complaints and questions (Table\u0026nbsp;1Q14). This motivated them to experiment with alternative ways of working, such as group consultations.\u003c/p\u003e \u003cp\u003eFinally, at the clinical, professional, and organisational levels the adaptability of the initiative to the local context was identified as a facilitator under the \u003cem\u003e\u0026lsquo;innovation adaptability\u0026rsquo;\u003c/em\u003e of the \u003cem\u003e\u0026lsquo;innovation\u0026rsquo;\u003c/em\u003e domain. The respondents underlined the importance of adapting these types of initiatives to the local context where they are implemented (Table\u0026nbsp;1Q15), for example, considering cultural sensitivity. They emphasised that these groups consultations allow adaptation to various local contexts due to the flexible character of the different components, for example, by focusing on specific themes that are relevant in neighbourhood (Table\u0026nbsp;1Q16).\u003c/p\u003e \u003cdiv id=\"Sec11\" class=\"Section2\"\u003e \u003ch2\u003eStrategies\u003c/h2\u003e \u003cp\u003eWe identified eight strategies that could be employed to improve the implementation of the group consultations (Table\u0026nbsp;\u003cspan refid=\"Tab2\" class=\"InternalRef\"\u003e2\u003c/span\u003e). We selected the strategy \u0026lsquo;\u003cem\u003einvolve patients/consumers and family members\u003c/em\u003e\u0026rsquo; to improve the involvement of citizens in the design of the group. Methods to employ this strategy could include training health champions, experts by experience who are motivated to help others, to aid in the recruitment of participants, preparation of group consultations, be present during group consultation, and guide participants after the initial group consultation. They can represent the local community and ensure that the intervention is adjusted to the needs of the participants.\u003c/p\u003e \u003cp\u003e \u003cdiv class=\"gridtable\"\u003e\u003ctable float=\"Yes\" id=\"Tab2\" border=\"1\"\u003e \u003ccaption language=\"En\"\u003e \u003cdiv class=\"CaptionNumber\"\u003eTable 2\u003c/div\u003e \u003cdiv class=\"CaptionContent\"\u003e \u003cp\u003eMain identified barriers and the matched strategy\u003c/p\u003e \u003c/div\u003e \u003c/caption\u003e \u003ccolgroup cols=\"2\"\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c1\" colnum=\"1\"\u003e\u003c/div\u003e \u003cdiv align=\"left\" class=\"colspec\" colname=\"c2\" colnum=\"2\"\u003e\u003c/div\u003e \u003cthead\u003e \u003ctr\u003e \u003cth align=\"left\" colname=\"c1\"\u003e \u003cp\u003eBarrier\u003c/p\u003e \u003c/th\u003e \u003cth align=\"left\" colname=\"c2\"\u003e \u003cp\u003eImplementation strategy from ERIC\u003c/p\u003e \u003c/th\u003e \u003c/tr\u003e \u003c/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003eLimited involvement of citizens in the design of the group consultations.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eInvolve patients/consumers and family members\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003eGap between the group consultations and local follow-up initiatives\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eOrganise clinician implementation team meetings\u003c/p\u003e \u003cp\u003eInvolve patients/consumers and family members\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003eThe lack of embedding of the group consultation into formal agreements/structures, resulting in dependence on the intrinsic motivation of involved partners for continuation of the initiative.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eDevelop a formal implementation blueprint\u003c/p\u003e \u003cp\u003eObtain formal commitments\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003eFragmentation of funding\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eUse other payment schemes\u003c/p\u003e \u003cp\u003eDevelop resource sharing agreements\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003ctr\u003e \u003ctd align=\"left\" colname=\"c1\"\u003e \u003cp\u003eInadequate evaluation of effectiveness and the implementation process.\u003c/p\u003e \u003c/td\u003e \u003ctd align=\"left\" colname=\"c2\"\u003e \u003cp\u003eCapture and share local knowledge\u003c/p\u003e \u003cp\u003eDevelop and organise quality monitoring systems\u003c/p\u003e \u003c/td\u003e \u003c/tr\u003e \u003c/tbody\u003e \u003c/colgroup\u003e \u003c/table\u003e\u003c/div\u003e \u003c/p\u003e \u003cp\u003eWe identified the strategies \u0026lsquo;\u003cem\u003einvolve patients/consumers and family members\u003c/em\u003e\u0026rsquo; and \u003cem\u003e\u0026lsquo;organise clinician implementation team meetings\u0026rsquo;\u003c/em\u003e to bridge the gap between the group consultations and local follow-up initiatives. The aforementioned health champions could guide participants during and after the initial group consultation to find appropriate support or care. Additionally, clinician, or in the case of a cross-domain initiative, interdisciplinary, implementation team meetings could be employed to develop a feedback system between professionals after the initial group consultation to increase involvement. Interdisciplinary team meetings with involved professionals could be organised to monitor progress and discuss how to handle loss to follow-up among participants. To support this process, the use of ICT tools could be explored to aid communication between professionals.\u003c/p\u003e \u003cp\u003eTo embed the group consultations into formal agreements/structures, two strategies were selected: \u003cem\u003e\u0026lsquo;develop a formal implementation blueprint\u0026rsquo;\u003c/em\u003e and \u003cem\u003e\u0026lsquo;obtain formal commitments\u0026rsquo;\u003c/em\u003e. By creating a roadmap for implementation, the fixed and flexible parts of the group consultation can be determined. Roles and procedures could then be formalised and embedded via formal agreements.\u003c/p\u003e \u003cp\u003eTo ensure sustainability, \u0026lsquo;\u003cem\u003euse other payment schemes\u003c/em\u003e\u0026rsquo; and \u0026lsquo;\u003cem\u003edevelop resource sharing agreements\u003c/em\u003e\u0026rsquo; were selected to overcome fragmentation of funding. Local agreements with the municipality and health insurance companies or national agreements are required for the payment structure.\u003c/p\u003e \u003cp\u003eFinally, we selected \u0026lsquo;\u003cem\u003ecapture and share local knowledge\u0026rsquo;\u003c/em\u003e and \u0026lsquo;\u003cem\u003edevelop and organise quality monitoring systems\u003c/em\u003e\u0026lsquo; to promote systematic evaluation of the effectiveness of the group consultations and their implementation process. Iterative quantitative and qualitative evaluations would promote implementation, including the formulation of results and outcomes, a structured data gathering process, and a formal process evaluation.\u003c/p\u003e \u003c/div\u003e"},{"header":"DISCUSSION","content":"\u003cp\u003e We evaluated the implementation barriers and facilitators of an integrated care initiative that adopts interprofessional collaborative practice of patient-centred care for individuals with prediabetes in the form of group consultations, specifically targeting socioeconomically vulnerable groups in the Hague, the Netherlands. The use of CFIR in combination with RMIC enabled the generation of knowledge about what works in different contexts, extending beyond the specific research setting. On the basis of these findings, we propose strategies to mitigate key barriers to improve implementation and upscaling.\u003c/p\u003e \u003cp\u003eKey barriers included insufficient citizen involvement in designing the intervention, which threatened normative integration because the content of the intervention was not adequately adjusted to meet the needs of the participants. As mentioned, normative integration is defined as the development and maintenance of a shared mission, vision, values and culture over the clinical, professional, organisational and system levels of the RMIC (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). When our findings are compared with those of previous studies, having citizen involvement in the design of the intervention seems to specifically influence the implementation of integrated care initiatives targeting socioeconomically vulnerable groups (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e). Discrepancies in the conceptualisation of health between healthcare professionals and socioeconomically vulnerable citizens highlight the importance of citizen involvement when targeting this group (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). A previous study indicated that health is perceived and defined differently depending on socioeconomic position (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). In this study, highly educated people focused on the importance of well-being when defining health, whereas lower educated people mainly perceived health as the absence of disease (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). When these different views on health are not considered when designing a health promotion programme, effectiveness might be reduced because the priorities and goals of professionals and participants do not align (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). To address this, we recommend involving patients/consumers and family members in the design process and adapting the intervention to the local context. Since every local context is unique, this strategy would remain important when scaling the intervention to new neighbourhoods or cities. This process is facilitated by the adaptability of the intervention, as the intervention is suitable for tweaking on the basis of local needs while keeping core elements the same.\u003c/p\u003e \u003cp\u003e The strategy of involving patients/consumers and family members was also proposed to bridge the gap between the group consultations and local follow-up initiatives, ensuring that participants receive appropriate and context sensitive information to choose suitable follow-ups. Additionally, organising interdisciplinary team meetings was suggested to establish a feedback system, thereby improving functional integration; so the supporting of and linking integration between the four levels of the RMIC (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e). In this way, follow-up and lost-to-follow-up can be monitored and discussed on a regular basis.\u003c/p\u003e \u003cp\u003eThe key facilitators of implementation were the sense of urgency for change and the widespread enthusiasm for the concept, which played a critical role in fostering normative integration. The perceived urgency for change and mission-driven motivation among initiators have previously been reported to drive bottom-up initiatives (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e). However, these other initiatives did encounter resistance from professionals who were supposed to collaborate in the new initiative, as they perceived the novel way of working as a violation of their professional autonomy (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e). We potentially did not pick up on this phenomenon in our study because we included only early adopters, so professionals who were enthusiastic about the intervention and therefore decided themselves to participate (\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e). It would be valuable to reevaluate these determinants of implementation during the process of adoption into standard care.\u003c/p\u003e \u003cp\u003eThe enthusiasm of professionals driving implementation might also have had an unintended side effect: the strong motivation of professionals to go the extra mile could have reduced the perceived necessity of embedding the intervention into formal health and social care structures. The fragmentation of funding further complicated functional integration, in line with previous findings in both the Dutch context (\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e, \u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e, \u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e, \u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e, \u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e) and internationally (\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e, \u003cspan additionalcitationids=\"CR15\" citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e). So although normative integration seemed to be going well, functional integration emerged as a challenge. This is a common phenomenon in bottom-up initiatives, where factors such as funding do not necessarily impede the initiation of change but become a barrier when initiatives move toward incorporation into standard practice (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e). For integrated care initiatives, there is an additional layer of complexity since, in the Netherlands, medical care and social support are governed by separate laws and funded through distinct budgets, thereby making the financing of these initiatives particularly challenging. This fragmentation often leads to the discontinuation of promising or even proven effective initiatives after their pilot phase due to the absence of sustainable funding (\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e, \u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe selected strategies to enhance functional integration include developing a formal implementation blueprint, obtaining formal commitments, exploring other payment schemes, and creating resource-sharing agreements. However, these last two strategies are complicated as real-world examples of sustainable payment models for integrated care initiatives that combine social and medical support remain scarce in the Dutch context. Nies et al. (2021) even described the separate reimbursement schemes for medical and social support as an \u0026ldquo;unsurmountable barrier\u0026rdquo; (\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e). Payers of both medical and social care\u0026mdash;health care insurers and municipalities, respectively\u0026mdash;are reluctant to invest in preventative activities because potential cost savings could fall under another budget (\u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e). Therefore, in line with our findings, they tend to point fingers to each other. This underlines the importance of creating resource-sharing agreements, including how to deal with potential savings, and indicates the need to explore payment options within or beyond the current siloed health and social system to address such issues.\u003c/p\u003e \u003cp\u003eFor scaling and sustainable implementation, an embedded systematic evaluation of the intervention's effectiveness and implementation process are important (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e). To address this, we propos capturing and sharing local knowledge and developing a quality monitoring system to drive ongoing improvements. The development of a learning health system would be an elegant example where these two strategies are combined (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e). In a learning health system, research and health care delivery, or integrated care delivery, are fused by embedding advanced research methods within the care trajectory (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e). Existing data infrastructures and insights from participants and professionals are used together to create rapid improvement cycles (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e). To improve equity, citizens should be involved in this process and whether all relevant perspectives are represented or whose voices are absent should be monitored (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e).\u003c/p\u003e \u003cdiv id=\"Sec13\" class=\"Section2\"\u003e \u003ch2\u003eStrengths and limitations\u003c/h2\u003e \u003cp\u003eA key strength of this study is the use of the RMIC framework in participant selection. By incorporating clinical, professional, organisational, and system-level perspectives, we ensured a diverse sample of respondents, representing various dimensions of implementation. Additionally, the use of the CFIR for data collection facilitated a broad focus during interviews and throughout the data collection process. During data analysis, this standardised determinants framework enabled the generation of knowledge about what works in different contexts, extending beyond the specific research setting. However, this approach carried the risk of a potential tunnel vision, focusing on the constructs within the framework and possibly overlooking themes outside its scope. Another limitation is the inclusion of early adopters in the study. Since the intervention has not yet been adopted into standard care, only early adopters working with the interventions exist. As a result, clinical, professional, and organisational integration may have been portrayed too optimistically, limiting the generalisability of findings beyond the scope of our research.\u003c/p\u003e \u003c/div\u003e"},{"header":"Conclusions","content":"\u003cp\u003e Citizen involvement in the design of the integrated care initiative was found to be a key determinant of implementation when targeting socioeconomically vulnerable groups. Although a shared sense of urgency for change and widespread enthusiasm among stakeholders were drivers of implementation and facilitated normative integration, they might have reduced the perceived necessity for functional integration. The lack of embedding of the initiative into formal structures and fragmented funding threatens its scalable and sustainable impact. Various strategies as defined by the ERIC taxonomy could be employed to promote implementation and upscaling. When targeting socioeconomically vulnerable groups, involving the target population in designing the intervention and adapting the intervention to the local context were found to be especially important. The absence of a sustainable funding structure was a main barrier when incorporating the integrated care initiative into standard care, regardless of the suitability of these initiatives to improve the health of socioeconomically vulnerable groups. The use of other payment schemes to surmount the separate reimbursement schemes for medical and social support could pose a suitable strategy to overcome this barrier. Embedded evaluation, possibly using a learning health system, is recommended for sustainable implementation and upscaling.\u003c/p\u003e"},{"header":"Abbreviations","content":"\u003cdiv class=\"DefinitionList\"\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eCFIR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eConsolidated Framework of Implementation Research\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eRMIC\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eRainbow Model of Integrated Care\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eERIC\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eExpert Recommendation for Implementing Change\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003enWMO\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eResearch not falling under the Dutch Medical Research with Human Subjects Law\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eQ\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eQuote\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003c/div\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cem\u003eEthics approval and consent to participate\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe Medical Ethical Review Board of Leiden University Medical Center mandated the review of research not falling under the Dutch Medical Research with Human Subjects Law (nWMO) to individual nWMO committees at Leiden University Medical Center. The nWMO committee reviewed the proposal and provided a declaration of no objection (non-WMO approval number: 24-3066). This study has been further approved by the scientific committee of the department of Public Health and Primary Care at Leiden University Medical Center (Reference number: WSC-2024-37).\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eAll the interviewees provided written informed consent. The participants in the focus group gave verbal consent after being informed about what data we would gather and how. No personal data were gathered during the focus group.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eConsent for publication\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eAll the interviewees provided written informed consent using an informed consent form approved by our institution.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eAvailability of data and materials\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets generated and analysed during the current study are not publicly available for privacy reasons.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eCompeting interests\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eFunding\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eMade possible in part by The Netherlands Organisation for Health Research and Development (ZonMw), file number 10390102210010.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eAuthors' contributions\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eJGtB and RCV conceived the study and developed the study design, with input from JKdJ. JGtB, TK, and MV gathered the data. JGtB, AFTME, and RCV designed the analyses. JGtB, AFTME, and RCV contributed to the data analyses and interpretation. JGtB drafted the manuscript, and all the authors contributed to editing the manuscript and approved the final submitted version.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eAcknowledgements\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eWe acknowledge Rianne Kleijn, Loïse M. Jacz-Kruithof, and Naomi Minderhout for evaluating our findings to assess accuracy and improve credibility. Furthermore, many thanks to all the respondents; we highly appreciate their insights, honesty, and time. \u0026nbsp;\u003c/p\u003e\n\u003cp\u003eAuthors’ information\u003c/p\u003e\n\u003cp\u003eJonne G. ter Braake, Annefrans F.T.M. van Ede, Jessica Kiefte-de Jong, and Rimke C. Vos work in research for an academic hospital. Jonne G. ter Braake is doing her PhD on social determinants of cardiovascular care; Annefrans F.T.M. van Ede works as a postdoc on the implementation of Population Health Management; Jessica Kiefte-de Jong is a professor of Population Health; and Rimke C. Vos works as an associate professor of implementation of Population Health Management. Jonne G. ter Braake was present during the group consultation’s implementation team meetings in 2024 and Rimke C. Vos has been part of the implementation team since 2019. Tara Kwakkernaat and Maud Verhoeven were both students at the time of this study and were involved in data collection as part of her bachelor’s dissertation in Health Policy and Management and her master’s dissertation in Population Heath Management, respectively.\u0026nbsp;\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eBeran M, Schram MT. Prediabetes in Nederland. 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BMJ Open. 2018;8(4):e020210.\u003c/li\u003e\n\u003cli\u003eKrijgsheld M, Schmidt E, Levels E, Schuurmans M. Healthcare professionals as change agents: Factors influencing bottom-up, personal initiatives on appropriate care, a qualitative study in the Netherlands. Health Policy. 2024;147:105120.\u003c/li\u003e\n\u003cli\u003eBerwick DM. Disseminating Innovations in Health Care. JAMA. 2003;289(15):1969-75.\u003c/li\u003e\n\u003cli\u003eHolterman S, Lahr M, Wynia K, Hettinga M, Buskens E. Integrated Care for Older Adults: A Struggle for Sustained Implementation in Northern Netherlands. International Journal of Integrated Care. 2020.\u003c/li\u003e\n\u003cli\u003eHilhorst P, Wijngaart Mvd. Samenwerking sociaal en medisch domein. Een verkenning. EMMA: EMMA; 2024.\u003c/li\u003e\n\u003cli\u003eEuropean Commission: Directorate-General for H, Food S. Blocks \u0026ndash; Tools and methodologies to assess integrated care in Europe \u0026ndash; Report by the Expert Group on Health Systems Performance Assessment: Publications Office; 2017.\u003c/li\u003e\n\u003cli\u003eReid RJ, Wodchis WP, Kuluski K, Lee-Foon NK, Lavis JN, Rosella LC, et al. Actioning the Learning Health System: An applied framework for integrating research into health systems. SSM - Health Systems. 2024;2:100010.\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"
[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Implementation determinants, socioeconomically vulnerable groups, integrated care, prediabetes, local initiative, bottom-up","lastPublishedDoi":"10.21203/rs.3.rs-5849625/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-5849625/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cb\u003eBackground\u003c/b\u003e\u003c/p\u003e \u003cp\u003eIntegrated care initiatives for socioeconomically vulnerable groups have the potential to deliver personalised care, enhance health outcomes, and foster greater equity within the healthcare system. However, the incorporation of these initiatives into standard care is rare. Insight into implementation barriers and facilitators to select strategies for further implementation and upscaling are therefore needed.\u003c/p\u003e\u003cp\u003e\u003cb\u003eMethods\u003c/b\u003e\u003c/p\u003e \u003cp\u003e We conducted a case study on an integrated care initiative adopting interprofessional collaborative practice of patient-centred care for citizens with prediabetes in the form of group consultations. We used a qualitative design guided by the Consolidated Framework of Implementation Research (CFIR) in combination with the Rainbow Model of Integrated Care. Semi-structured interviews and a focus group were conducted among stakeholders, including health and social care professionals, policy makers, and experts by experience. We used Framework analysis to analyse the data. We matched implementation strategies to a selection of barriers using CFIR\u0026rsquo;s Expert Recommendations of Implementation Research matching tool.\u003c/p\u003e\u003cp\u003e\u003cb\u003eResults\u003c/b\u003e\u003c/p\u003e \u003cp\u003eWe conducted 28 interviews and one focus group (n\u0026thinsp;=\u0026thinsp;16). Key barriers included insufficient involvement of citizens in the design of the group consultations, which could be overcome by involving patients/consumers and family members in the design of the group consultations. Additionally, we identified a lack of embedding in the current healthcare system and fragmentation of funding as barriers. By developing a formal implementation blueprint, obtaining formal commitments, using other payment schemes, and developing resource sharing agreements, these barriers could be addressed. Finally, inadequate evaluation was identified as a barrier. This could be improved by capturing and sharing local knowledge and developing and organising a quality monitoring system. Key facilitators were the widespread enthusiasm for the concept of group consultations, a sense of urgency for change, and the adaptability of the initiative to the local context.\u003c/p\u003e\u003cp\u003e\u003cb\u003eConclusions\u003c/b\u003e\u003c/p\u003e \u003cp\u003eCitizen involvement in the design of an integrated care initiative, such as group consultations, is a key determinant of implementation when targeting socioeconomically vulnerable groups. Further research is needed to explore payment options within or beyond the current siloed health and social systems.\u003c/p\u003e","manuscriptTitle":"Implementation Barriers and Facilitators of an Integrated Care Initiative Targeting Socioeconomically Vulnerable Groups","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-03-12 11:48:45","doi":"10.21203/rs.3.rs-5849625/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"
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