[Clinicopathological study of endometrial-type adenocarcinoma of uterus]

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This clinicopathological study of 71 endometrial-type adenocarcinomas found most were well-differentiated, with lymphatic and venous invasion and lymph node metastasis more frequent in diffuse, introversive, moderately-differentiated, and deeply invasive types.

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Abstract

Seventy-one resected cases of endometrial-type adenocarcinoma of uterus were clinicopathologically investigated. As to the gross findings, the incidence of localized type and diffuse type was 47.9% and 52.1%, while that of extroversive type and introversive type was 59.1% and 40.9%, respectively. The incidence of the lesions less than 3 cm in diameter was 36.7% and that beyond 5 cm was 28.1%. The majority (88.7%) of the endometrial-type adenocarcinoma were histologically well-differentiated. Concerning depth of invasion, the incidence of the cases of intramucosal invasion, invasion within 1/3 of muscle layer, invasion between 1/3 and 2/3 of muscle layer, and invasion beyond 2/3 of muscle layer was 19.7%, 46.5%, 16.9%, and 16.9%, respectively. Lymphatic and venous invasion were more frequently found in diffuse, introversive, moderately-differentiated, and deep invasive types than the other types. Lymph nodal metastasis was found in 9.8% of all cases (16.2% in diffuse type, 20.8% in introversive type, 33.3% in moderately-differentiated type and 41.7% in the cases beyond 2/3 of muscle layer).

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Uterine Neoplasms Adenocarcinoma Adult Aged Endometriosis Female Humans Lymphatic Metastasis Middle Aged Neoplasm Invasiveness Uterine Neoplasms

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europepmc
last seen: 2026-08-13T06:15:24.848197+00:00
pubmed
last seen: 2026-05-13T22:12:10.587122+00:00
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