Robert's uterus with adenomyosis: A case report and review of the literature

Robert's uterus with adenomyosis: A case report and review of the literature | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Robert's uterus with adenomyosis: A case report and review of the literature Yangyang Rao, Min Chen, Yiju LI This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4143655/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 08 Aug, 2024 Read the published version in BMC Women's Health → Version 1 posted 4 You are reading this latest preprint version Abstract Purpose To provide the differential diagnosis and determine the treatment of Robert's uterus with adenomyosis, a rare uterine malformation. Methods A patient who had Robert’s uterus with adenomyosis was admitted to our hospital in December 2022; we analyzed and summarized her case. Results Ourpatient complained of progressively worsening primary dysmenorrhea over 3 years and lower abdominal pain lasting for 2 days. Her level of carbohydrate antigens 125 (CA125) was 372.10 U/mL. Examinations in several hospitals indicated that she had a single-horned uterus as well as a residual horned uterus. In our hospital, we found the malformation described by Robert. This was corrected by open abdominal surgery as follows:During the procedure, pelvic adhesions were first isolated, then the closed uterine cavity and adenomyosis were resected. Subsequently, the left ovarian endometriosis cyst was resected, and right tubal ligation was performed. After surgery, three injections of gonadotropin-releasing hormone A (GnRH-A) were given, which lowered the patient’s CA125 to 14 U/mL and normalized her condition. Conclusion In this work, wepioneered a new therapeutic approach for the treatment of Robert's uterus with adenomyosis andprovide a valuable reference for clinical practice. Robert's uterus uterine malformations dysmenorrhea adenomyosis Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 08 Aug, 2024 Read the published version in BMC Women's Health → Version 1 posted Editorial decision: Revision requested 28 Mar, 2024 Submission checks completed at journal 22 Mar, 2024 Editor assigned by journal 22 Mar, 2024 First submitted to journal 21 Mar, 2024 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4143655","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":282738939,"identity":"612b67f3-f145-40c2-8cd3-9d6371fda065","order_by":0,"name":"Yangyang Rao","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAvElEQVRIiWNgGAWjYBACfmbmgw8/VNTY8ROtRbKdLdlY4syxZMkGYrUY9POYCfC2MTNuOEC0FmYeMwYJNjZm4+PJGxh+VGwjrMWcma3sQQGPDJ/ZmWcFjD1nbhPWYtnMvN1AQoKN2exGjgEzYxsRWgwOM5hJ8AAVb55BvBYWoJYEoPcliNUi2QwK5APHkiWAfjlIlF/4+Q8ffPjxHzAq25M3PvhRQYQWJJBgcIAk9WAtpOoYBaNgFIyCEQIAUK04+yzr78UAAAAASUVORK5CYII=","orcid":"","institution":"","correspondingAuthor":true,"prefix":"","firstName":"Yangyang","middleName":"","lastName":"Rao","suffix":""},{"id":282738940,"identity":"24ccc0c7-3fca-4dee-9616-c18dade97fa4","order_by":1,"name":"Min Chen","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"Min","middleName":"","lastName":"Chen","suffix":""},{"id":282738941,"identity":"71d92554-3858-4c48-a945-abea3b81dd64","order_by":2,"name":"Yiju LI","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"Yiju","middleName":"","lastName":"LI","suffix":""}],"badges":[],"createdAt":"2024-03-21 12:54:29","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-4143655/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-4143655/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1186/s12905-024-03286-7","type":"published","date":"2024-08-08T15:56:55+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":62298147,"identity":"d2e328e5-503d-497d-8138-9495cf60067e","added_by":"auto","created_at":"2024-08-12 16:09:02","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":530027,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript1.pdf","url":"https://assets-eu.researchsquare.com/files/rs-4143655/v1_covered_2a38b9d6-eac6-44a2-8e79-76cd018fd211.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Robert's uterus with adenomyosis: A case report and review of the literature","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"bmc-womens-health","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bmwh","sideBox":"Learn more about [BMC Women's Health](http://bmcwomenshealth.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bmwh/default.aspx","title":"BMC Women's Health","twitterHandle":"","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Robert's uterus, uterine malformations, dysmenorrhea, adenomyosis","lastPublishedDoi":"10.21203/rs.3.rs-4143655/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-4143655/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003ePurpose \u003c/strong\u003eTo provide the differential diagnosis and determine the treatment of Robert's uterus with adenomyosis, a rare uterine malformation.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods \u003c/strong\u003eA patient who had Robert’s uterus with adenomyosis was admitted to our hospital in December 2022; we analyzed and summarized her case.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e Ourpatient complained of progressively worsening primary dysmenorrhea over 3 years and lower abdominal pain lasting for 2 days. 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