Plants Used in Endometriosis in Females

Ectopic endometrial tissue growth is the hallmark of endometriosis, a persistent gynecological disorder that causes infertility, dysmenorrhea, and pelvic pain. Although they provide symptom relief, conventional medications including NSAIDs, hormonal contraceptives, GnRH agonists, and progestins are frequently linked to side effects like bone loss, hormonal imbalances, and gastrointestinal problems. Medicinal plants have drawn attention as substitute therapeutic agents in light of these drawbacks. Numerous herbal extracts have shown anti-inflammatory, anti-angiogenic, and immunomodulatory qualities in experimental models. These include Urtica dioica , Achillea cretica , Ocimum basilicum , Boswellia serrata , Calligonum comosum , Cyperus rotundus , and Zingiber officinale . Among these, U. dioica methanol extract showed promise as a treatment by considerably lowering inflammatory cytokines and lesion size. A viable strategy for managing endometriosis is combining herbal medication with traditional therapies.