Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriosis
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PD-ECGF is expressed in ovarian endometrioma lining epithelial and subepithelial interstitial cells, persisting throughout the menstrual cycle to potentially drive growth via angiogenesis independent of sex steroids.
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Abstract
Platelet-derived endothelial cell growth factor (PD-ECGF) is expressed in the lining epithelial cells of ovarian endometriomas, and in interstitial cells of the subepithelial area with angiogenesis. The expression of PD-ECGF persists in endometriotic endometrium during the menstrual cycle. This might suggest that PD-ECGF contributes to the growth of ovarian endometriomas via subepithelial angiogenesis independently of the sex steroidal milieu.
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- europepmc
- last seen: 2026-10-17T06:09:56.316927+00:00
- pubmed
- last seen: 2026-10-08T22:00:54.229014+00:00
- unpaywall
- last seen: 2026-05-14T19:30:52.867331+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine