Endometriosis - clinical approach based on histological findings.

C Cristescu, Andreea Velişcu, B Marinescu, Bogdan Marinescu, Anca Pătraşcu, E Traşcă, E T Traşcă, Oltin T. Pop, O T Pop
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie · 2013 · vol. 54(1) , pp. 91–7 · PMID:23529314 · W3723402
article OA: closed CC0 ⤵ 7 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-14 ⓘ

Medroxyprogesterone administration for six months after endometriosis surgery prevented recurrence in all patients, while Triptorelinum did not.

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Abstract

Endometriosis is a benign disease defined by the presence of endometrial glands and stroma outside of the uterus and is associated with both pelvic pain and infertility. The most common sites of endometriosis, in decreasing order of frequency, are the ovaries, anterior and posterior cul-de-sac, posterior broad ligaments, uterosacral ligaments, uterus, fallopian tubes, sigmoid colon, appendix, and round ligaments. The main treatment is surgical, but often-microscopic islands of endometrial tissue remain, which proliferate and are responsible for relapses. We tested the efficacy of two drugs (Medroxyprogesterone and Triptorelinum), administered for six months to prevent recurrence after surgery. Treatment with Medroxyprogesterone was 100% effective in terms of relapse, while Triptorelinum could not prevent recurrence of endometriosis.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Adolescent Adult Endometriosis Endometriosis Endometriosis Female Humans Middle Aged Young Adult

Citation neighborhood

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Cited by (7)

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europepmc
last seen: 2026-06-20T06:14:18.781669+00:00
openalex
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pubmed
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License: CC0 · commercial use OK