Phytotherapy impact on peristalsis of unpregnant uterus in women with adenomyosis

In: Reproductive Endocrinology · 2013 · vol. 0(9) , pp. 64 · doi:10.18370/2309-4117.2013.9.64-66 · W254130360
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This study found that the herbal drug Tazalok reduced uterine dysperistalsis and pain in women with adenomyosis.

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The paper studied uterine peristalsis in unpregnant women with adenomyosis, assessing whether abnormal subendometrial myometrial contractions (dysperistalsis waves) occur versus healthy women. It reports that women with adenomyosis have uterine peristalsis disorders manifested as dysperistalsis waves that were not found in healthy controls, and that the drug Tazalok 40 given three times daily for two months led to a statistically significant reduction in uterine dysperistalsis and pain. The main stated limitation is that the abstract provides only high-level outcomes without details on study design, sample size, or the magnitude/duration of follow-up. This paper is centrally about adenomyosis — it focuses specifically on dysperistalsis in the myometrium and the effects of Tazalok 40 in women with adenomyosis.

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Abstract

One of the little-known mechanisms of infertility because of adenomyosis (аденомиоз, аденоміоз) is peristalsis disorders of subendometrial layers of the myometrium. The study showed that in women with adenomyosis there is a violation of the uterine peristalsis as dysperistalsis waves that are not found in healthy women. Administration the drug Tazalok 40 in a dose drops 3 times a day for 2 months caused a statistically significant reduction of uterine dysperistalsis in women with adenomyosis and a significant reduction of pain.
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Phytotherapy impact on peristalsis of unpregnant uterus in women with adenomyosis DOI: https://doi.org/10.18370/2309-4117.2013.9.64-66Keywords: adenomyosis, uterus, myometrium, dysperistalsis wavesAbstract One of the little-known mechanisms of infertility because of adenomyosis (аденомиоз, аденоміоз) is peristalsis disorders of subendometrial layers of the myometrium. The study showed that in women with adenomyosis there is a violation of the uterine peristalsis as dysperistalsis waves that are not found in healthy women. Administration the drug Tazalok 40 in a dose drops 3 times a day for 2 months caused a statistically significant reduction of uterine dysperistalsis in women with adenomyosis and a significant reduction of pain.References - Battista G Mild endometriosis and infertility: A clinical rewiew of epidemiologic data, diagnostic pitfalls, and classification limits // Obstet. Gynecol. Surv. – 1991. Vol. 46. – P. 374-379. - Bartosik D, Damjanov I, Viscarello RR Immunoproteins in the endometrium: clinical correlates of the presence of complement fractions C3 and C4. // Am. J. Obstet. Gynecol. – 1987. – Vol. 156. – P. 11-15. - Bulletti C, Ziegler DD, Rossi S, Negrini V, Alfieri S, Massoneau M Retrograde efflux of endometrial debris during menstruation in women with endometriosis // J. Am. Ass. Gynecol. Laparoscop. – 1997. – Vol. 4, № 4. – P. 17. - Fernandez-Shaw S, Hicks BR, Yudkin PL Antiendometrial and anti-endothelial auto-antibodies in women with endometriosis // Hum. Reprod. – 1993. – Vol. 8. – P. 310-315. - Kissler S, Wildt L, Kohl J, Ahr A, Kaufmann M, Siebzehnrubl E Gestorte Transportfunction in der Hysterosalpingoszintigraphie (HSSG) als prodiktiver Functionstest für die Durchführung einer IVF-Therapie // Zentralbl Gynakol. – 2002. – Vol. 124. – P. 418-422. - Lyons EA, Taylor PJ, Zheng XH, Ballard G, Levi CS, Kredentser JV Characterization of subendometrial myometrial contractions throughout the menstrual cycle in normal fertile women // Fertil. Steril. – 1991. – Vol. 55. – P. 771-775. - Adamyan LV, Kulakov VI Endometriosis. Guidelines for physicians. – Moscow: Medicine, 1998. – 320 p. - Baskakov VP, Tsvelev YV, Kira EF Endometrial disease. – Saint-Petersburg.: Publishing H-L, 2002. – C. 36-37. - Burlev VA, Volkov NI, Stygar AS et al. The value of growth factors in endometriosis pathogenesis // Russian Obstetric and Gynecological Assoc. Journal. – 1999. – № 1. – P. 55-56. - Gladchuk IZ Operative endoscopy in treatment of women infertility: thesis for the MD degree. – Odessa, 1999. – 35 p. - Gladchuk IZ, Rogachevsky AP Results of hysterosalpingoscintigraphy in infertile women with pelvic endometriosis at various sites // Medicine today and tomorrow. – 2005. – № 3. – P. 119-125. - Zaporozhan VM, Gladchuk IZ, Rogachevsky AP, Baumann R Features of intrauterine transport of albumins microspheres labeled by isotope Tc-99m in infertile women with endometriosis // PAG. – 2005. – № 5. – P. 98-102. Downloads Published How to Cite Issue Section License Copyright (c) 2014 А. П. Рогачевский This work is licensed under a Creative Commons Attribution 4.0 International License. Authors who publish with this journal agree to the following terms: - Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

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adenomyosisinfertility

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