Ovarian endometriosis and the risk of malignancy

Objective To explore the clinical and pathological characteristics of ovarian endometriosis and malignant cases,and to improve our recognition of this disease. Methods A total of 1 289 cases of ovarian endometriosis were divided into two groups: the benign group(1 275 cases)and the malignant group(14 cases).They were analyzed on: dysmenorrhea,infertility,features of ultrasound examination,site of tumour,pathological types and complications. Results Malignancy arising from ovarian endometriosis was 1.09%.As far as degree of dysmenorrhea,size of cyst 10 cm,CA125 500 U/L,features of ultrasound were concerned,difference between the two groups was statistically significant. Conclusions In the present study,the malignant rate of ovarian endometriosis was about 1%.Malignancy should be considered seriously when the following situations occured: change in the degree of dysmenorrhea,size of cyst larger than 10 cm,CA125 higher than 500 U/L,mamilla observed by ultrasound examination.