A Rare Case of Ovarian Clear Cell Carcinoma Arising from an Endometriotic Cyst: A Case Report

Endometriosis, characterized by ectopic endometrial tissue outside the uterus, commonly affects the ovaries and peritoneum. While generally benign, it has been linked to an increased risk of ovarian cancer, termed endometriosis-associated ovarian cancer (EAOC). Case Illustration: A 32-year-old woman experienced abdominal distension and a sense of fullness for one year. A gynecological examination revealed a right adnexal mass. Transvaginal ultrasound showed an enlarged uterus with adenomyosis features and a hyperhypoechoic, multilocular right adnexal mass (11.44 x 9.61 cm) with vascularization and septations. Transabdominal ultrasound indicated a complex ovarian cyst, bilateral mild hydronephrosis, and no metastases. Blood tests showed elevated CA-125 (318.60 U/mL), CA 19-9 (110.33 U/mL), and a high Risk of Malignancy Index (RMI: 955.80). Surgery included total abdominal hysterectomy, right salpingo-oophorectomy, omentectomy, and adhesiolysis. Pathological analysis confirmed endometriosis with atypical cells and clear cell carcinoma, classified as FIGO stage IIB. Post-surgery, the patient received six cycles of carboplatin and paclitaxel chemotherapy.

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A Rare Case of Ovarian Clear Cell Carcinoma Arising from an Endometriotic Cyst: A Case Report. Indonesia Journal of Biomedical Science, 18(2), 246–251. https://doi.org/10.15562/ijbs.v18i2.595 Ida Bagus Gede Fajar Manuaba Google Scholar Pubmed IJBS Journal Putu Doster Mahayasa Google Scholar Pubmed IJBS Journal Made Bagus Dwi Aryana Google Scholar Pubmed IJBS Journal DPG Jananuraga Maharddhika Google Scholar Pubmed IJBS Journal - Postgraduate School of Biomedicine - Udayana University, Bali-Indonesia - 62 (0361) 224556 - 62 (0361) 224556 - [email protected] Copyright © DiscoverSys Inc