Poremećaji agregacije trombocita u žena s endometriozom

Major progress has been seen in the past few decades in the management of gynecological conditions and obstetric care in women with bleeding disorders (BDs). However, there remain many ambiguous issues within the field. A sequence of observational studies was conducted to address these issues with a goal to improve patient care. In the recent findings showing that platelets play important roles in the development of endometriosis. Hence, this review was undertaken to see if there was a connection between bleeding disorders specially platelet aggregation defect and endometriosis. This association was explored in animal models as well as in clinical studies suggesting that women with endometriosis have a higher rate of platelet aggregation defect. Deficiency of von Willebrand factor (VWF), a protein required for the normal adhesion of platelets to the site of injured endothelium may be associated with advanced stage of endometriosis on laparoscopy. The present review concludes that platelets may be a culprit in the development of endometriosis and that platelet aggregation were seen in endometriotic lesions.