Clinical observation on treatment of endometriosis with acupuncture plus herbs

Yu Fu, Tian Xia
In: Journal of Acupuncture and Tuina Science · 2005 · vol. 3(5) , pp. 48–51 · doi:10.1007/bf02845583 · W2326707484
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This study compared acupuncture plus herbs with danazol for endometriosis, finding similar overall efficacy but superior improvements in pain, menstruation, infertility, and reduced CA125 and prostaglandins in the herbal group.

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This randomized controlled trial evaluated the clinical efficacy of combined acupuncture and herbal medicine versus danazol in seventy-eight patients diagnosed with endometriosis. The study measured changes in symptoms such as lumbosacral pain and infertility, alongside serum biomarkers including CA125, PGE2, PGF2α, and β-EP. Results indicated that while overall efficacy was similar between groups, the acupuncture and herb group demonstrated significantly better improvement in specific pelvic symptoms and favorable modulation of inflammatory and pain-related markers with fewer adverse reactions. This paper is centrally about endometriosis — specifically comparing an integrative traditional Chinese medicine treatment approach against a standard Western pharmaceutical intervention for managing the condition's symptoms and biochemical markers.

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Abstract

Objective: To compare the clinical efficacy of combined acupuncture and herbs with danazol in treating endometriosis. Methods: Seventy-eight patients were randomly divided into a combined acupuncture and herbs group (n=40) and a Western medicine control group (n=38). Observation was made on changes in clinical symptoms, signs, serum CA125, β-EP, PGE2 and PGF2α, and adverse reaction to the medicine in the two groups. Results: The overall efficacy was similar in the two groups, but the effects on lumbosacral pain, anal downbearing distention, irregular menstruation and infertility were significantly better in the treatment group than in the control group (P<0.05), and in the treatment group serum CA125, PGE2 and PGF2α, were significantly lower and serum β-EP was significantly higher after treatment than before (P<0.05). Conclusion: Combined use of acupuncture and herbs has a marked effect on endometriosis and the adverse reaction is lower than the control group. Similar content being viewed by others

References

Gurates B, Bulun SE. Endometriosis: the ultimate hormonal disease, Semin Rep roduc Med, 2003, 21(2): 125–134. Diagnostic and Treatment Criteria of Endometriosis by Integrative Chinese-Western Medicine, the 3rd academic conference of Specialty Committee of Gynccology. China Association of Integrative Chinese-Western Medicine. China Journal of Integrative Chinese-Western Medicine, 1991, 11(6): 376. LE Jie. Obstetrics and Gynecology. 5th Edition. Beijing: the People's Health Press, 2000: 387–395. ZHENG Li-xuan. Role of EMAb and CA125 Assay in Diagnosis of Micro- or Mild-Endometriosis, Journal of Chinese Modern Medicine, 2003, 13 (7): 67–68. Noble Ls, Sinpson ER, Johns A, et al. A romatase expression in endometriosis, Clin Endocrinol Metdb. 1996, 81(1): 174–179. Author information Authors and Affiliations Additional information Author: FU Yu (1970-), male, attending physician, PhD Translator: HAN Chou-ping ({ie51-1}) Rights and permissions About this article Cite this article Yu, F., Tian, X. Clinical observation on treatment of endometriosis with acupuncture plus herbs. J. Acupunct. Tuina. Sci. 3, 48–51 (2005). https://doi.org/10.1007/BF02845583 Received: Issue date: DOI: https://doi.org/10.1007/BF02845583

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endometriosis

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