[Clinical and experimental study on the treatment of endometriosis with dan'e mixture].

OBJECTIVE: To find a medicine to treat endometriosis effectively with less side-effect. METHODS: Dan'e mixture (DEM, consists of Radix Salviae Miltiorrhizae and Rhizoma Zedoariae) was used to treat 189 cases of endometriosis and the change of symptom and sign, the B ultrasonograph, the anti-endometrium antibody and endometriosis quantitative diagnostic index were observed, another 160 cases were treated with Danazol as control, also using animal model to treat with DEM and Danazol. RESULTS: One hundred and eighty-nine cases were treated for 9 months. According to National Standards, 39 cases (20.6%) were cured, 67 cases (35.4%) were markedly effective, 67 cases (35.4%) were effective, and 16 cases (8.4%) were ineffective. Compared with 160 cases treated with Danazol for 9 months, the total effective rates were 95% and 91.5% respectively, the difference between them was insignificant. Animal experiments showed the similar results to the clinical ones. CONCLUSION: SZM is a safe and effective medicine to treat endometriosis, which deserves further study and development. It is particularly helpful for diagnosis, treatment and prevention of endometriosis in the early stage.