Preoperative therapy in preparation for endometrial ablation.
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Abstract
In order to improve the success of endometrial ablation for uncontrolled uterine bleeding, a variety of preoperative agents were utilized. Patients were given either no preparation, progestins, danazol or leuprolide acetate depot as preoperative therapy to determine the best way to increase the incidence of amenorrhea and to decrease the failure rates. The lowest rates were achieved with danazol or no preparation, with amenorrhea rates of 41 and 43%, respectively. The highest rates were obtained with the use of either progestins or leuprolide acetate depot, 61 and 67%, respectively. Progestin use was discontinued early in the study because of side effects, resulting in numbers too low for accurate comparison. We concluded that the use of leuprolide acetate depot in a single-dose regimen resulted in the highest amenorrhea rates, with minimal or no side effects.
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Cited by (12)
- Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding 2013
- Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding 2002
- Hysteroscopic endometrial destruction, optimum method for preoperative endometrial preparation: a prospective, randomized, multicenter evaluation. 2002
- Is endometrial pre-treatment of value in improving the outcome of transcervical resection of the endometrium? 2000
- Efficacy of preoperative medical treatment in facilitating hysteroscopic endometrial resection, myomectomy and metroplasty: literature review 1998
- Medical preparation of the endometrium prior to resection: Decapeptyl SR (triptorelin) versus danazol versus placebo 1998
- Resumption of menstruation after amenorrhea in women treated by endometrial ablation and myometrial resection 1997
- Administration of medroxyprogesterone acetate after endomyometrial resection 1997
- Hormonal inhibition of endometrium for transcervical endometrial ablation-a prospective study with a 2-year follow-up 1997
- Treatment with a gonadotrophin releasing hormone agonist before endometrial resection: a multicentre, randomised controlled trial 1996
- Endometrial Ablation: Complications and Outcome 1996
- HYSTEROSCOPIC ENDOMETRIAL ABLATION 1995
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