Atypical polypoid adenomyoma of the uterus. An immunohistochemical study of a case
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Immunohistochemical analysis of a uterine atypical polypoid adenomyoma revealed stromal cells with muscular phenotypes, supporting its distinction from other endometrial tumors.
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Abstract
We studied one case of atypical polypoid adenomyoma of the uerus immunohistochemically using antisera against keratins, vinentin, S-100 protein, desmin and actin. The stromal cells were reactive with anti-actin and antidesmin antibodies suggesting a muscular phenotype and confirming previous ultrastructural data. Immunohistochemical investigations have proved to be useful in differential diagnosis of APA with invasive adenocarcinoma, adenosarcoma and adenofibroma of the endometrium.
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- europepmc
- last seen: 2026-08-23T09:30:01.253652+00:00
- pubmed
- last seen: 2026-05-13T22:09:10.744835+00:00
- unpaywall
- last seen: 2026-08-28T06:28:33.284919+00:00
License: public-domain-us
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine