Effects of Non-Essential Protein On D-Glucose to Control Diabetes: DFT Approach

Abstract Diabetes is a disease found in every 1 out of 4 people in the world. The glucose molecule is one of the sources of energy in the body and the lack of the digestion of glucose causes diabetes type 1 and type 2. Arginine and Cysteine is a nonessential amino acid that contains sulfur and help to maintain the metabolisms of humans. We explored the Glucose-Arginine (Glc-arg) and Glucose-Cysteine (Glc-cys) molecules by finding their structural properties, electronic properties, chemical reactivity, mechanical strength and transport properties because these non-essential amino acids molecules inhibit glucose-stimulated insulin secretion. Density functional theory (DFT) have been implemented to study all the properties of Glc-arg and Glc-cys using SIESTA software. Glucose-Arginine (Glc-arg) inhibits a large percentage of glucose secretion and shows high chemical reactivity.